[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone

C107H105Cl8N19O9 — CID 159722379

About [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone

[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone (PubChem CID 159722379) has the molecular formula C107H105Cl8N19O9 and a molecular weight of 2084.76 g/mol. Its IUPAC name is [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone.

Molecular Properties

• Compound Name: [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
• PubChem CID: 159722379
• Molecular Formula: C107H105Cl8N19O9
• Molecular Weight: 2084.76 g/mol
• Exact Mass: 2079.59
• IUPAC Name: [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone
• SMILES: CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(N(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(O)C4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl
• InChI: InChI=1S/2C28H29Cl2N5O2.C26H25Cl2N5O2.C25H22Cl2N4O3/c1-17(26-23(29)15-31-16-24(26)30)37-21-8-9-25-22(14-21)27(33-32-25)18-4-6-19(7-5-18)28(36)35-12-10-20(11-13-35)34(2)3;1-17(2)34-10-12-35(13-11-34)28(36)20-6-4-19(5-7-20)27-22-14-21(8-9-25(22)32-33-27)37-18(3)26-23(29)15-31-16-24(26)30;1-16(24-21(27)14-29-15-22(24)28)35-19-7-8-23-20(13-19)25(31-30-23)17-3-5-18(6-4-17)26(34)33-11-9-32(2)10-12-33;1-14(23-20(26)11-28-12-21(23)27)34-18-6-7-22-19(10-18)24(30-29-22)15-2-4-16(5-3-15)25(33)31-9-8-17(32)13-31/h4-9,14-17,20H,10-13H2,1-3H3,(H,32,33);4-9,14-18H,10-13H2,1-3H3,(H,32,33);3-8,13-16H,9-12H2,1-2H3,(H,30,31);2-7,10-12,14,17,32H,8-9,13H2,1H3,(H,29,30)
• InChIKey: NAEWRNDRZPCAMD-UHFFFAOYSA-N
• XLogP: 23.21
• TPSA: 314.39 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 20
• Rotatable Bonds: 22
• Heavy Atoms: 143
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2084.76
LogP ≤ 5	23.21
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone?

The IUPAC name of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone (CID 159722379) is [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone.

What is the SMILES notation for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone?

The canonical SMILES for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone is CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(N(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCC(O)C4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C(C)C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.CC(Oc1ccc2[nH]nc(-c3ccc(C(=O)N4CCN(C)CC4)cc3)c2c1)c1c(Cl)cncc1Cl.

What is the InChIKey of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone?

The InChIKey is NAEWRNDRZPCAMD-UHFFFAOYSA-N. The full InChI is InChI=1S/2C28H29Cl2N5O2.C26H25Cl2N5O2.C25H22Cl2N4O3/c1-17(26-23(29)15-31-16-24(26)30)37-21-8-9-25-22(14-21)27(33-32-25)18-4-6-19(7-5-18)28(36)35-12-10-20(11-13-35)34(2)3;1-17(2)34-10-12-35(13-11-34)28(36)20-6-4-19(5-7-20)27-22-14-21(8-9-25(22)32-33-27)37-18(3)26-23(29)15-31-16-24(26)30;1-16(24-21(27)14-29-15-22(24)28)35-19-7-8-23-20(13-19)25(31-30-23)17-3-5-18(6-4-17)26(34)33-11-9-32(2)10-12-33;1-14(23-20(26)11-28-12-21(23)27)34-18-6-7-22-19(10-18)24(30-29-22)15-2-4-16(5-3-15)25(33)31-9-8-17(32)13-31/h4-9,14-17,20H,10-13H2,1-3H3,(H,32,33);4-9,14-18H,10-13H2,1-3H3,(H,32,33);3-8,13-16H,9-12H2,1-2H3,(H,30,31);2-7,10-12,14,17,32H,8-9,13H2,1H3,(H,29,30).

What are the key properties of [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone?

[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone has a molecular weight of 2084.76 g/mol, XLogP of 23.21, 22 rotatable bonds, 5 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for [4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(3-hydroxypyrrolidin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-methylpiperazin-1-yl)methanone;[4-[5-[1-(3,5-dichloro-4-pyridinyl)ethoxy]-1H-indazol-3-yl]phenyl]-(4-propan-2-ylpiperazin-1-yl)methanone is sourced from PubChem (CID 159722379), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).