2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide

C136H115Cl2F3N26O13S8 — CID 159748842

About 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide

2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide (PubChem CID 159748842) has the molecular formula C136H115Cl2F3N26O13S8 and a molecular weight of 2706.02 g/mol. Its IUPAC name is 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide.

Molecular Properties

• Compound Name: 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide
• PubChem CID: 159748842
• Molecular Formula: C136H115Cl2F3N26O13S8
• Molecular Weight: 2706.02 g/mol
• Exact Mass: 2702.62
• IUPAC Name: 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide
• SMILES: COc1cccc(C(O)C(=O)Nc2nc(-c3ccncc3)cs2)c1.Cc1ccc(C)c(C(O)C(=O)Nc2nc(-c3ccncc3)cs2)c1.NC(Cc1cccc(F)c1F)C(=O)Nc1nc(-c2ccncc2)cs1.NC(Cc1ccccc1Cl)C(=O)Nc1nc(-c2ccncc2)cs1.O=C(CCc1cccc(Cl)c1)Nc1nc(-c2ccncc2)cs1.O=C(CCc1ccccc1F)Nc1nc(-c2ccncc2)cs1.O=C(CCc1ccccc1O)Nc1nc(-c2ccncc2)cs1.O=C(Nc1nc(-c2ccncc2)cs1)C(=O)c1ccccc1
• InChI: InChI=1S/C18H17N3O2S.C17H15ClN4OS.C17H14ClN3OS.C17H14F2N4OS.C17H14FN3OS.C17H15N3O3S.C17H15N3O2S.C16H11N3O2S/c1-11-3-4-12(2)14(9-11)16(22)17(23)21-18-20-15(10-24-18)13-5-7-19-8-6-13;18-13-4-2-1-3-12(13)9-14(19)16(23)22-17-21-15(10-24-17)11-5-7-20-8-6-11;18-14-3-1-2-12(10-14)4-5-16(22)21-17-20-15(11-23-17)13-6-8-19-9-7-13;18-12-3-1-2-11(15(12)19)8-13(20)16(24)23-17-22-14(9-25-17)10-4-6-21-7-5-10;18-14-4-2-1-3-12(14)5-6-16(22)21-17-20-15(11-23-17)13-7-9-19-10-8-13;1-23-13-4-2-3-12(9-13)15(21)16(22)20-17-19-14(10-24-17)11-5-7-18-8-6-11;21-15-4-2-1-3-13(15)5-6-16(22)20-17-19-14(11-23-17)12-7-9-18-10-8-12;20-14(12-4-2-1-3-5-12)15(21)19-16-18-13(10-22-16)11-6-8-17-9-7-11/h3-10,16,22H,1-2H3,(H,20,21,23);1-8,10,14H,9,19H2,(H,21,22,23);1-3,6-11H,4-5H2,(H,20,21,22);1-7,9,13H,8,20H2,(H,22,23,24);1-4,7-11H,5-6H2,(H,20,21,22);2-10,15,21H,1H3,(H,19,20,22);1-4,7-11,21H,5-6H2,(H,19,20,22);1-10H,(H,18,19,21)
• InChIKey: NDJUBXUAOTUZOP-UHFFFAOYSA-N
• XLogP: 27.59
• TPSA: 578.07 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 39
• Rotatable Bonds: 38
• Heavy Atoms: 188
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2706.02
LogP ≤ 5	27.59
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	39

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'diketo_group', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide?

The IUPAC name of 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide (CID 159748842) is 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide.

What is the SMILES notation for 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide?

The canonical SMILES for 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide is COc1cccc(C(O)C(=O)Nc2nc(-c3ccncc3)cs2)c1.Cc1ccc(C)c(C(O)C(=O)Nc2nc(-c3ccncc3)cs2)c1.NC(Cc1cccc(F)c1F)C(=O)Nc1nc(-c2ccncc2)cs1.NC(Cc1ccccc1Cl)C(=O)Nc1nc(-c2ccncc2)cs1.O=C(CCc1cccc(Cl)c1)Nc1nc(-c2ccncc2)cs1.O=C(CCc1ccccc1F)Nc1nc(-c2ccncc2)cs1.O=C(CCc1ccccc1O)Nc1nc(-c2ccncc2)cs1.O=C(Nc1nc(-c2ccncc2)cs1)C(=O)c1ccccc1.

What is the InChIKey of 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide?

The InChIKey is NDJUBXUAOTUZOP-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H17N3O2S.C17H15ClN4OS.C17H14ClN3OS.C17H14F2N4OS.C17H14FN3OS.C17H15N3O3S.C17H15N3O2S.C16H11N3O2S/c1-11-3-4-12(2)14(9-11)16(22)17(23)21-18-20-15(10-24-18)13-5-7-19-8-6-13;18-13-4-2-1-3-12(13)9-14(19)16(23)22-17-21-15(10-24-17)11-5-7-20-8-6-11;18-14-3-1-2-12(10-14)4-5-16(22)21-17-20-15(11-23-17)13-6-8-19-9-7-13;18-12-3-1-2-11(15(12)19)8-13(20)16(24)23-17-22-14(9-25-17)10-4-6-21-7-5-10;18-14-4-2-1-3-12(14)5-6-16(22)21-17-20-15(11-23-17)13-7-9-19-10-8-13;1-23-13-4-2-3-12(9-13)15(21)16(22)20-17-19-14(10-24-17)11-5-7-18-8-6-11;21-15-4-2-1-3-13(15)5-6-16(22)20-17-19-14(11-23-17)12-7-9-18-10-8-12;20-14(12-4-2-1-3-5-12)15(21)19-16-18-13(10-22-16)11-6-8-17-9-7-11/h3-10,16,22H,1-2H3,(H,20,21,23);1-8,10,14H,9,19H2,(H,21,22,23);1-3,6-11H,4-5H2,(H,20,21,22);1-7,9,13H,8,20H2,(H,22,23,24);1-4,7-11H,5-6H2,(H,20,21,22);2-10,15,21H,1H3,(H,19,20,22);1-4,7-11,21H,5-6H2,(H,19,20,22);1-10H,(H,18,19,21).

What are the key properties of 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide?

2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide has a molecular weight of 2706.02 g/mol, XLogP of 27.59, 38 rotatable bonds, 13 hydrogen bond donors, and 39 hydrogen bond acceptors.

Where does this data come from?

All data for 2-amino-3-(2-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-amino-3-(2,3-difluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;3-(3-chlorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-(2,5-dimethylphenyl)-2-hydroxy-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-fluorophenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-hydroxy-2-(3-methoxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide;3-(2-hydroxyphenyl)-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)propanamide;2-oxo-2-phenyl-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide is sourced from PubChem (CID 159748842), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).