N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide

C152H143F11N18O8 — CID 159754685

About N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide

N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide (PubChem CID 159754685) has the molecular formula C152H143F11N18O8 and a molecular weight of 2558.91 g/mol. Its IUPAC name is N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide.

Molecular Properties

• Compound Name: N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide
• PubChem CID: 159754685
• Molecular Formula: C152H143F11N18O8
• Molecular Weight: 2558.91 g/mol
• Exact Mass: 2557.12
• IUPAC Name: N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide
• SMILES: CCc1ccc(-c2cccnc2[C@@H](Cc2ccccc2)NC(=O)Cc2c[nH]c3ccc(O)cc23)cc1.CCc1ccc(-c2cccnc2[C@H](Cc2ccccc2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)cc1.COc1ccc(-c2cccnc2[C@@H](Cc2ccccc2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)cc1.Cc1ccccc1-c1cccnc1[C@H](Cc1cccc(F)c1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@H](Cc1cccc(F)c1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2
• InChI: InChI=1S/C31H31F3N4O.C31H29N3O2.C30H28F4N4O.C30H29F3N4O2.C30H26FN3O2/c1-2-21-14-16-23(17-15-21)24-12-8-18-35-29(24)26(19-22-9-4-3-5-10-22)36-28(39)20-38-27-13-7-6-11-25(27)30(37-38)31(32,33)34;1-2-21-10-12-23(13-11-21)26-9-6-16-32-31(26)29(17-22-7-4-3-5-8-22)34-30(36)18-24-20-33-28-15-14-25(35)19-27(24)28;1-19-8-2-3-11-22(19)23-13-7-15-35-28(23)25(17-20-9-6-10-21(31)16-20)36-27(39)18-38-26-14-5-4-12-24(26)29(37-38)30(32,33)34;1-39-22-15-13-21(14-16-22)23-11-7-17-34-28(23)25(18-20-8-3-2-4-9-20)35-27(38)19-37-26-12-6-5-10-24(26)29(36-37)30(31,32)33;1-19-6-2-3-9-24(19)25-10-5-13-32-30(25)28(15-20-7-4-8-22(31)14-20)34-29(36)16-21-18-33-27-12-11-23(35)17-26(21)27/h3-5,8-10,12,14-18,26H,2,6-7,11,13,19-20H2,1H3,(H,36,39);3-16,19-20,29,33,35H,2,17-18H2,1H3,(H,34,36);2-3,6-11,13,15-16,25H,4-5,12,14,17-18H2,1H3,(H,36,39);2-4,7-9,11,13-17,25H,5-6,10,12,18-19H2,1H3,(H,35,38);2-14,17-18,28,33,35H,15-16H2,1H3,(H,34,36)/t26-;29-;2*25-;28-/m01010/s1
• InChIKey: NECJVJUJFDWVRW-IEGLPMTCSA-N
• XLogP: 31.01
• TPSA: 344.68 Ų
• H-Bond Donors: 9
• H-Bond Acceptors: 19
• Rotatable Bonds: 38
• Heavy Atoms: 189
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2558.91
LogP ≤ 5	31.01
H-Bond Donors ≤ 5	9
H-Bond Acceptors ≤ 10	19

Frequently Asked Questions

What is the IUPAC name of N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The IUPAC name of N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide (CID 159754685) is N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide.

What is the SMILES notation for N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The canonical SMILES for N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide is CCc1ccc(-c2cccnc2[C@@H](Cc2ccccc2)NC(=O)Cc2c[nH]c3ccc(O)cc23)cc1.CCc1ccc(-c2cccnc2[C@H](Cc2ccccc2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)cc1.COc1ccc(-c2cccnc2[C@@H](Cc2ccccc2)NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)cc1.Cc1ccccc1-c1cccnc1[C@H](Cc1cccc(F)c1)NC(=O)Cc1c[nH]c2ccc(O)cc12.Cc1ccccc1-c1cccnc1[C@H](Cc1cccc(F)c1)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2.

What is the InChIKey of N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

The InChIKey is NECJVJUJFDWVRW-IEGLPMTCSA-N. The full InChI is InChI=1S/C31H31F3N4O.C31H29N3O2.C30H28F4N4O.C30H29F3N4O2.C30H26FN3O2/c1-2-21-14-16-23(17-15-21)24-12-8-18-35-29(24)26(19-22-9-4-3-5-10-22)36-28(39)20-38-27-13-7-6-11-25(27)30(37-38)31(32,33)34;1-2-21-10-12-23(13-11-21)26-9-6-16-32-31(26)29(17-22-7-4-3-5-8-22)34-30(36)18-24-20-33-28-15-14-25(35)19-27(24)28;1-19-8-2-3-11-22(19)23-13-7-15-35-28(23)25(17-20-9-6-10-21(31)16-20)36-27(39)18-38-26-14-5-4-12-24(26)29(37-38)30(32,33)34;1-39-22-15-13-21(14-16-22)23-11-7-17-34-28(23)25(18-20-8-3-2-4-9-20)35-27(38)19-37-26-12-6-5-10-24(26)29(36-37)30(31,32)33;1-19-6-2-3-9-24(19)25-10-5-13-32-30(25)28(15-20-7-4-8-22(31)14-20)34-29(36)16-21-18-33-27-12-11-23(35)17-26(21)27/h3-5,8-10,12,14-18,26H,2,6-7,11,13,19-20H2,1H3,(H,36,39);3-16,19-20,29,33,35H,2,17-18H2,1H3,(H,34,36);2-3,6-11,13,15-16,25H,4-5,12,14,17-18H2,1H3,(H,36,39);2-4,7-9,11,13-17,25H,5-6,10,12,18-19H2,1H3,(H,35,38);2-14,17-18,28,33,35H,15-16H2,1H3,(H,34,36)/t26-;29-;2*25-;28-/m01010/s1.

What are the key properties of N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide?

N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide has a molecular weight of 2558.91 g/mol, XLogP of 31.01, 38 rotatable bonds, 9 hydrogen bond donors, and 19 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(1R)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-1-[3-(4-ethylphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-(5-hydroxy-1H-indol-3-yl)acetamide;N-[(1S)-2-(3-fluorophenyl)-1-[3-(2-methylphenyl)-2-pyridinyl]ethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide;N-[(1R)-1-[3-(4-methoxyphenyl)-2-pyridinyl]-2-phenylethyl]-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]acetamide is sourced from PubChem (CID 159754685), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).