7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one

C155H131F25N26O14 — CID 159768817

IUPAC7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one
SMILESCOc1cc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)ccn1.COc1ccc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)cn1.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3cc(-c4cnccn4)n(-c4ccc(F)c(C(F)(F)F)c4)n3)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4cc[nH]c(=O)c4)c3C)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4ccc(=O)[nH]c4)c3C)CC1)C(=O)C2
InChIInChI=1S/2C32H28F5N5O3.2C31H26F5N5O3.C29H23F5N6O2/c1-17-4-5-19-14-26(43)41(30(19)27(17)34)21-10-12-40(13-11-21)31(44)28-18(2)29(20-6-9-25(45-3)38-16-20)42(39-28)22-7-8-24(33)23(15-22)32(35,36)37;1-17-4-5-19-15-26(43)41(30(19)27(17)34)21-9-12-40(13-10-21)31(44)28-18(2)29(20-8-11-38-25(14-20)45-3)42(39-28)22-6-7-24(33)23(16-22)32(35,36)37;1-16-3-4-18-13-25(43)40(29(18)26(16)33)20-9-11-39(12-10-20)30(44)27-17(2)28(19-5-8-24(42)37-15-19)41(38-27)21-6-7-23(32)22(14-21)31(34,35)36;1-16-3-4-18-14-25(43)40(29(18)26(16)33)20-8-11-39(12-9-20)30(44)27-17(2)28(19-7-10-37-24(42)13-19)41(38-27)21-5-6-23(32)22(15-21)31(34,35)36;1-16-2-3-17-12-25(41)39(27(17)26(16)31)18-6-10-38(11-7-18)28(42)22-14-24(23-15-35-8-9-36-23)40(37-22)19-4-5-21(30)20(13-19)29(32,33)34/h4-9,15-16,21H,10-14H2,1-3H3;4-8,11,14,16,21H,9-10,12-13,15H2,1-3H3;3-8,14-15,20H,9-13H2,1-2H3,(H,37,42);3-7,10,13,15,20H,8-9,11-12,14H2,1-2H3,(H,37,42);2-5,8-9,13-15,18H,6-7,10-12H2,1H3
InChIKeyNFVTTXBAASWSEG-UHFFFAOYSA-N
MW3056.87 g/mol
LogP27.90
Rot. Bonds22

About 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one

7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one (PubChem CID 159768817) has the molecular formula C155H131F25N26O14 and a molecular weight of 3056.87 g/mol. Its IUPAC name is 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one.

Molecular Properties

Compound Name7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one
PubChem CID159768817
Molecular FormulaC155H131F25N26O14
Molecular Weight3056.87 g/mol
Exact Mass3054.99
IUPAC Name7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one
SMILESCOc1cc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)ccn1.COc1ccc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)cn1.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3cc(-c4cnccn4)n(-c4ccc(F)c(C(F)(F)F)c4)n3)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4cc[nH]c(=O)c4)c3C)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4ccc(=O)[nH]c4)c3C)CC1)C(=O)C2
InChIInChI=1S/2C32H28F5N5O3.2C31H26F5N5O3.C29H23F5N6O2/c1-17-4-5-19-14-26(43)41(30(19)27(17)34)21-10-12-40(13-11-21)31(44)28-18(2)29(20-6-9-25(45-3)38-16-20)42(39-28)22-7-8-24(33)23(15-22)32(35,36)37;1-17-4-5-19-15-26(43)41(30(19)27(17)34)21-9-12-40(13-10-21)31(44)28-18(2)29(20-8-11-38-25(14-20)45-3)42(39-28)22-6-7-24(33)23(16-22)32(35,36)37;1-16-3-4-18-13-25(43)40(29(18)26(16)33)20-9-11-39(12-10-20)30(44)27-17(2)28(19-5-8-24(42)37-15-19)41(38-27)21-6-7-23(32)22(14-21)31(34,35)36;1-16-3-4-18-14-25(43)40(29(18)26(16)33)20-8-11-39(12-9-20)30(44)27-17(2)28(19-7-10-37-24(42)13-19)41(38-27)21-5-6-23(32)22(15-21)31(34,35)36;1-16-2-3-17-12-25(41)39(27(17)26(16)31)18-6-10-38(11-7-18)28(42)22-14-24(23-15-35-8-9-36-23)40(37-22)19-4-5-21(30)20(13-19)29(32,33)34/h4-9,15-16,21H,10-14H2,1-3H3;4-8,11,14,16,21H,9-10,12-13,15H2,1-3H3;3-8,14-15,20H,9-13H2,1-2H3,(H,37,42);3-7,10,13,15,20H,8-9,11-12,14H2,1-2H3,(H,37,42);2-5,8-9,13-15,18H,6-7,10-12H2,1H3
InChIKeyNFVTTXBAASWSEG-UHFFFAOYSA-N
XLogP27.90
TPSA427.94 Ų
H-Bond Donors2
H-Bond Acceptors28
Rotatable Bonds22
Heavy Atoms220
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003056.87
LogP ≤ 527.90
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 1028

Analyze 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one with MolForge

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Related Compounds

N-cyclohexyl-4-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]benzamide;N-(3,3-diphenylpropyl)-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide;N-hexyl-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide;N-methyl-N-pyridin-4-yl-4-[5-pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzamide;4-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-N-[4-(trifluoromethoxy)phenyl]benzamide
CID 157055530
CID 157066093
CID 157066093
1-[1-[1-[2,5-difluoro-4-(trifluoromethyl)phenyl]-5-pyridin-3-ylpyrazole-3-carbonyl]piperidin-4-yl]-7-fluoro-6-methyl-3H-indol-2-one;2-fluoro-4-[3-[4-(7-fluoro-6-methyl-2-oxo-3H-indol-1-yl)piperidine-1-carbonyl]-5-pyridin-3-ylpyrazol-1-yl]benzonitrile;1-(4-fluoro-3-methylphenyl)-8-[1-[2-methyl-4-(trifluoromethoxy)phenyl]-5-pyridin-3-ylpyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one;1-(4-fluorophenyl)-8-[1-[2-methyl-4-(trifluoromethoxy)phenyl]-5-pyridin-3-ylpyrazole-3-carbonyl]-1,8-diazaspiro[4.5]decan-4-one
CID 157192545
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(2-fluorophenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(2-fluorophenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(2-fluorophenoxy)-3-pyridinyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[6-(2-fluorophenoxy)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;methane
CID 157230427
(2S)-5,5-difluoro-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-5-(6-methoxy-3-pyridinyl)-2-(4-methylcyclohexyl)-4-oxopentanamide;(2S)-2-(4,4-dimethylcyclohexyl)-4-(2-ethylpyrazol-3-yl)-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-4-oxobutanamide;4-(2-ethylpyrazol-3-yl)-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-2-[1-(4-fluorophenyl)ethyl]-4-oxobutanamide;2-[2-(2-ethylpyrazol-3-yl)-2-oxoethyl]-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-3-phenylpentanamide
CID 157292115
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylphenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylphenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-methylphenoxy)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157297533
N-[3-butyl-2-methoxy-5-(trifluoromethyl)phenyl]-3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-4-methylbenzamide;N-[3-(2-cyclobutylethyl)-2-methoxy-5-(trifluoromethyl)phenyl]-3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-4-methylbenzamide;N-[3-(2-cyclopentylethyl)-2-methoxy-5-(trifluoromethyl)phenyl]-3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-4-methylbenzamide;N-[3-[(dimethylamino)methyl]-2-methoxy-5-(trifluoromethyl)phenyl]-3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-4-methylbenzamide;N-[2-methoxy-3-(3-methylbutyl)-5-(trifluoromethyl)phenyl]-3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-4-methylbenzamide;3-[4-(5-methoxy-3-pyridinyl)triazol-1-yl]-N-[2-methoxy-3-(pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)phenyl]-4-methylbenzamide
CID 157410897
(2S)-2-[(1S)-1-cyclohexylethyl]-5,5-difluoro-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-5-(6-methoxy-3-pyridinyl)-4-oxopentanamide;(2S)-2-[(1S)-1-cyclohexylethyl]-4-(2-ethylpyrazol-3-yl)-N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-4-oxobutanamide;N-[(3S,4R)-4-cyclohexyloxy-1-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-2-oxopentan-3-yl]-2-ethylpyrazole-3-carboxamide;N-[2-fluoro-4-[(2S,3R)-4-(4-methylpiperazin-1-yl)-4-oxo-3-(propanoylamino)butan-2-yl]phenyl]-2-[1-(4-fluorophenyl)ethyl]-4-oxo-4-(2-propan-2-ylpyrazol-3-yl)butanamide
CID 157450549
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylphenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(4-methylphenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(4-methylphenoxy)-3-pyridinyl]-5-(5-piperidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide;N-[6-(4-methylphenoxy)-3-pyridinyl]-5-(5-pyrrolidin-1-yl-3-pyridinyl)-1H-indazole-3-carboxamide
CID 157463681
(4R)-4-[3-(7H-cyclopenta[b]pyridin-3-yl)-2-pyridinyl]-1-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-5-(3,5-difluorophenyl)pentan-2-one;(4R)-4-[3-[3-(2-cyclopropylacetyl)phenyl]-2-pyridinyl]-5-(3,5-difluorophenyl)-1-[3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl]pentan-2-one;5-[2-[(1S)-1-[[2-(4,6-dimethyl-2-oxo-1,3-dihydroindol-3-yl)acetyl]amino]-2-(3-fluorophenyl)ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;3-fluoro-5-[2-[(1S)-1-[[2-(5-fluoro-1H-indol-3-yl)acetyl]amino]-2-(3-fluoro-5-methylphenyl)ethyl]-3-pyridinyl]-N-methylbenzamide;2-(5-fluoro-1H-indol-3-yl)-N-[(1S)-2-(3-fluoro-5-methylphenyl)-1-[3-(6-methoxy-3-pyridinyl)-2-pyridinyl]ethyl]acetamide
CID 157549720
5-[5-[(4,4-difluoropiperidin-1-yl)methyl]-3-pyridinyl]-N-[6-(2-fluorophenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;5-[5-[(3,3-difluoropyrrolidin-1-yl)methyl]-3-pyridinyl]-N-[6-(2-fluorophenoxy)-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(3-fluorophenoxy)-3-pyridinyl]-5-[5-[(4-hydroxypiperidin-1-yl)methyl]-3-pyridinyl]-1H-indazole-3-carboxamide;N-[6-(3-fluorophenoxy)-3-pyridinyl]-5-[5-(oxan-4-ylamino)-3-pyridinyl]-1H-indazole-3-carboxamide
CID 157601319
5-[2-[(1S)-1-[[2-(9-cyano-5,5-difluoro-7,8-diazatricyclo[4.3.0.02,4]nona-1(6),8-dien-7-yl)acetyl]amino]-2-(3,5-difluorophenyl)ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;5-[2-[(1S)-2-(3,5-difluorophenyl)-1-[[2-(5-fluoro-2-oxo-1,3-dihydroindol-3-yl)acetyl]amino]ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;5-[2-[(1S)-2-(3,5-difluorophenyl)-1-[[2-(6-methoxy-2-oxo-1,3-dihydroindol-3-yl)acetyl]amino]ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;5-[2-[(1S)-2-(3,5-difluorophenyl)-1-[[2-(6-methyl-2-oxo-1,3-dihydroindol-3-yl)acetyl]amino]ethyl]-3-pyridinyl]-2-fluoro-N-methylbenzamide;2-fluoro-5-[2-[(1S)-2-(3-fluorophenyl)-1-[[2-(2-oxo-1H-quinolin-4-yl)acetyl]amino]ethyl]-3-pyridinyl]-N-methylbenzamide
CID 157609576

Frequently Asked Questions

What is the IUPAC name of 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one?
The IUPAC name of 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one (CID 159768817) is 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one.
What is the SMILES notation for 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one?
The canonical SMILES for 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one is COc1cc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)ccn1.COc1ccc(-c2c(C)c(C(=O)N3CCC(N4C(=O)Cc5ccc(C)c(F)c54)CC3)nn2-c2ccc(F)c(C(F)(F)F)c2)cn1.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3cc(-c4cnccn4)n(-c4ccc(F)c(C(F)(F)F)c4)n3)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4cc[nH]c(=O)c4)c3C)CC1)C(=O)C2.Cc1ccc2c(c1F)N(C1CCN(C(=O)c3nn(-c4ccc(F)c(C(F)(F)F)c4)c(-c4ccc(=O)[nH]c4)c3C)CC1)C(=O)C2.
What is the InChIKey of 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one?
The InChIKey is NFVTTXBAASWSEG-UHFFFAOYSA-N. The full InChI is InChI=1S/2C32H28F5N5O3.2C31H26F5N5O3.C29H23F5N6O2/c1-17-4-5-19-14-26(43)41(30(19)27(17)34)21-10-12-40(13-11-21)31(44)28-18(2)29(20-6-9-25(45-3)38-16-20)42(39-28)22-7-8-24(33)23(15-22)32(35,36)37;1-17-4-5-19-15-26(43)41(30(19)27(17)34)21-9-12-40(13-10-21)31(44)28-18(2)29(20-8-11-38-25(14-20)45-3)42(39-28)22-6-7-24(33)23(16-22)32(35,36)37;1-16-3-4-18-13-25(43)40(29(18)26(16)33)20-9-11-39(12-10-20)30(44)27-17(2)28(19-5-8-24(42)37-15-19)41(38-27)21-6-7-23(32)22(14-21)31(34,35)36;1-16-3-4-18-14-25(43)40(29(18)26(16)33)20-8-11-39(12-9-20)30(44)27-17(2)28(19-7-10-37-24(42)13-19)41(38-27)21-5-6-23(32)22(15-21)31(34,35)36;1-16-2-3-17-12-25(41)39(27(17)26(16)31)18-6-10-38(11-7-18)28(42)22-14-24(23-15-35-8-9-36-23)40(37-22)19-4-5-21(30)20(13-19)29(32,33)34/h4-9,15-16,21H,10-14H2,1-3H3;4-8,11,14,16,21H,9-10,12-13,15H2,1-3H3;3-8,14-15,20H,9-13H2,1-2H3,(H,37,42);3-7,10,13,15,20H,8-9,11-12,14H2,1-2H3,(H,37,42);2-5,8-9,13-15,18H,6-7,10-12H2,1H3.
What are the key properties of 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one?
7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one has a molecular weight of 3056.87 g/mol, XLogP of 27.90, 22 rotatable bonds, 2 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for 7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(2-methoxy-4-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-(6-methoxy-3-pyridinyl)-4-methylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(2-oxo-1H-pyridin-4-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-4-methyl-5-(6-oxo-1H-pyridin-3-yl)pyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one;7-fluoro-1-[1-[1-[4-fluoro-3-(trifluoromethyl)phenyl]-5-pyrazin-2-ylpyrazole-3-carbonyl]piperidin-4-yl]-6-methyl-3H-indol-2-one is sourced from PubChem (CID 159768817), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).