1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide

C98H119F9N22O9 — CID 159772109

About 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide

1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide (PubChem CID 159772109) has the molecular formula C98H119F9N22O9 and a molecular weight of 1920.16 g/mol. Its IUPAC name is 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide.

Molecular Properties

• Compound Name: 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide
• PubChem CID: 159772109
• Molecular Formula: C98H119F9N22O9
• Molecular Weight: 1920.16 g/mol
• Exact Mass: 1918.94
• IUPAC Name: 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide
• SMILES: CCN(c1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)cc2c(-c3ccnc(N(C)C)c3)ncn12)C1CCN(CC(F)(F)F)CC1.CCN(c1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)cc2c(-c3ccnc(NC)c3)ncn12)C1CCN(CC(F)(F)F)CC1.CNc1cc(-c2ccn3c(C(C)C4CCN(CC(F)(F)F)CC4)c(C)c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc23)ccn1
• InChI: InChI=1S/C33H41F3N8O3.C33H39F3N6O3.C32H39F3N8O3/c1-7-43(23-9-12-42(13-10-23)18-33(34,35)36)32-21(3)24(30(45)38-17-25-27(47-6)14-20(2)40-31(25)46)16-26-29(39-19-44(26)32)22-8-11-37-28(15-22)41(4)5;1-19-14-28(45-5)26(32(44)40-19)17-39-31(43)25-16-27-24(23-6-10-38-29(15-23)37-4)9-13-42(27)30(21(25)3)20(2)22-7-11-41(12-8-22)18-33(34,35)36;1-6-42(22-8-11-41(12-9-22)17-32(33,34)35)31-20(3)23(29(44)38-16-24-26(46-5)13-19(2)40-30(24)45)15-25-28(39-18-43(25)31)21-7-10-37-27(14-21)36-4/h8,11,14-16,19,23H,7,9-10,12-13,17-18H2,1-6H3,(H,38,45)(H,40,46);6,9-10,13-16,20,22H,7-8,11-12,17-18H2,1-5H3,(H,37,38)(H,39,43)(H,40,44);7,10,13-15,18,22H,6,8-9,11-12,16-17H2,1-5H3,(H,36,37)(H,38,44)(H,40,45)
• InChIKey: NGGBSJCPJAYAQX-UHFFFAOYSA-N
• XLogP: 14.76
• TPSA: 334.75 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 25
• Rotatable Bonds: 29
• Heavy Atoms: 138
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1920.16
LogP ≤ 5	14.76
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide?

The IUPAC name of 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide (CID 159772109) is 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide.

What is the SMILES notation for 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide?

The canonical SMILES for 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide is CCN(c1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)cc2c(-c3ccnc(N(C)C)c3)ncn12)C1CCN(CC(F)(F)F)CC1.CCN(c1c(C)c(C(=O)NCc2c(OC)cc(C)[nH]c2=O)cc2c(-c3ccnc(NC)c3)ncn12)C1CCN(CC(F)(F)F)CC1.CNc1cc(-c2ccn3c(C(C)C4CCN(CC(F)(F)F)CC4)c(C)c(C(=O)NCc4c(OC)cc(C)[nH]c4=O)cc23)ccn1.

What is the InChIKey of 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide?

The InChIKey is NGGBSJCPJAYAQX-UHFFFAOYSA-N. The full InChI is InChI=1S/C33H41F3N8O3.C33H39F3N6O3.C32H39F3N8O3/c1-7-43(23-9-12-42(13-10-23)18-33(34,35)36)32-21(3)24(30(45)38-17-25-27(47-6)14-20(2)40-31(25)46)16-26-29(39-19-44(26)32)22-8-11-37-28(15-22)41(4)5;1-19-14-28(45-5)26(32(44)40-19)17-39-31(43)25-16-27-24(23-6-10-38-29(15-23)37-4)9-13-42(27)30(21(25)3)20(2)22-7-11-41(12-8-22)18-33(34,35)36;1-6-42(22-8-11-41(12-9-22)17-32(33,34)35)31-20(3)23(29(44)38-16-24-26(46-5)13-19(2)40-30(24)45)15-25-28(39-18-43(25)31)21-7-10-37-27(14-21)36-4/h8,11,14-16,19,23H,7,9-10,12-13,17-18H2,1-6H3,(H,38,45)(H,40,46);6,9-10,13-16,20,22H,7-8,11-12,17-18H2,1-5H3,(H,37,38)(H,39,43)(H,40,44);7,10,13-15,18,22H,6,8-9,11-12,16-17H2,1-5H3,(H,36,37)(H,38,44)(H,40,45).

What are the key properties of 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide?

1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide has a molecular weight of 1920.16 g/mol, XLogP of 14.76, 29 rotatable bonds, 8 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[2-(dimethylamino)-4-pyridinyl]-5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methylimidazo[1,5-a]pyridine-7-carboxamide;5-[ethyl-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]amino]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]imidazo[1,5-a]pyridine-7-carboxamide;N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-6-methyl-1-[2-(methylamino)-4-pyridinyl]-5-[1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indolizine-7-carboxamide is sourced from PubChem (CID 159772109), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).