N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine

C122H135F14N39O3S — CID 159773944

About N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine

N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine (PubChem CID 159773944) has the molecular formula C122H135F14N39O3S and a molecular weight of 2493.73 g/mol. Its IUPAC name is N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine.

Molecular Properties

• Compound Name: N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
• PubChem CID: 159773944
• Molecular Formula: C122H135F14N39O3S
• Molecular Weight: 2493.73 g/mol
• Exact Mass: 2492.11
• IUPAC Name: N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine
• SMILES: CC1(C)C[C@@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@@H]1c1cn[nH]c1.CC1(C)C[C@@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H]1c1cn[nH]c1.CC1(C)C[C@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@@H]1c1cn[nH]c1.CC1(C)C[C@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H]1c1cn[nH]c1.CC1C(CNS(C)(=O)=O)N(C2COC2)CCN1c1ccnc(-c2cnc3ccc(C(F)F)cn23)n1
• InChI: InChI=1S/4C25H27F3N8.C22H27F2N7O3S/c4*1-24(2)9-18(24)13-34-7-8-35(15-20(34)16-10-31-32-11-16)22-5-6-29-23(33-22)19-12-30-21-4-3-17(14-36(19)21)25(26,27)28;1-14-17(10-27-35(2,32)33)30(16-12-34-13-16)8-7-29(14)20-5-6-25-22(28-20)18-9-26-19-4-3-15(21(23)24)11-31(18)19/h4*3-6,10-12,14,18,20H,7-9,13,15H2,1-2H3,(H,31,32);3-6,9,11,14,16-17,21,27H,7-8,10,12-13H2,1-2H3/t2*18-,20+;2*18-,20-;/m1010./s1
• InChIKey: NGMGZIAATKIAGX-LEEDUXIASA-N
• XLogP: 19.33
• TPSA: 417.92 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 37
• Rotatable Bonds: 27
• Heavy Atoms: 179
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2493.73
LogP ≤ 5	19.33
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	37

Frequently Asked Questions

What is the IUPAC name of N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?

The IUPAC name of N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CID 159773944) is N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine.

What is the SMILES notation for N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?

The canonical SMILES for N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine is CC1(C)C[C@@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@@H]1c1cn[nH]c1.CC1(C)C[C@@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H]1c1cn[nH]c1.CC1(C)C[C@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@@H]1c1cn[nH]c1.CC1(C)C[C@H]1CN1CCN(c2ccnc(-c3cnc4ccc(C(F)(F)F)cn34)n2)C[C@H]1c1cn[nH]c1.CC1C(CNS(C)(=O)=O)N(C2COC2)CCN1c1ccnc(-c2cnc3ccc(C(F)F)cn23)n1.

What is the InChIKey of N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?

The InChIKey is NGMGZIAATKIAGX-LEEDUXIASA-N. The full InChI is InChI=1S/4C25H27F3N8.C22H27F2N7O3S/c4*1-24(2)9-18(24)13-34-7-8-35(15-20(34)16-10-31-32-11-16)22-5-6-29-23(33-22)19-12-30-21-4-3-17(14-36(19)21)25(26,27)28;1-14-17(10-27-35(2,32)33)30(16-12-34-13-16)8-7-29(14)20-5-6-25-22(28-20)18-9-26-19-4-3-15(21(23)24)11-31(18)19/h4*3-6,10-12,14,18,20H,7-9,13,15H2,1-2H3,(H,31,32);3-6,9,11,14,16-17,21,27H,7-8,10,12-13H2,1-2H3/t2*18-,20+;2*18-,20-;/m1010./s1.

What are the key properties of N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine?

N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine has a molecular weight of 2493.73 g/mol, XLogP of 19.33, 27 rotatable bonds, 5 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-[[4-[2-[6-(difluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-yl]-3-methyl-1-(oxetan-3-yl)piperazin-2-yl]methyl]methanesulfonamide;3-[4-[(3R)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1R)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3R)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine;3-[4-[(3S)-4-[[(1S)-2,2-dimethylcyclopropyl]methyl]-3-(1H-pyrazol-4-yl)piperazin-1-yl]pyrimidin-2-yl]-6-(trifluoromethyl)imidazo[1,2-a]pyridine is sourced from PubChem (CID 159773944), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).