N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate

C152H117Br8Cl6F3N38O2S — CID 159774927

About N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate

N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate (PubChem CID 159774927) has the molecular formula C152H117Br8Cl6F3N38O2S and a molecular weight of 3448.88 g/mol. Its IUPAC name is N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate.

Molecular Properties

• Compound Name: N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate
• PubChem CID: 159774927
• Molecular Formula: C152H117Br8Cl6F3N38O2S
• Molecular Weight: 3448.88 g/mol
• Exact Mass: 3436.15
• IUPAC Name: N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate
• SMILES: Brc1cnc2c(NCc3cncnc3)cc(-c3ccccc3)cn12.CC(C)(C)OC(=O)Nc1cc(CNc2cc(-c3ccccc3)cn3c(Br)cnc23)ncn1.Clc1ccccc1-c1cc(NCc2cccnc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2ccncc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2cncnc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2nccs2)c2ncc(Br)n2c1.FC(F)(F)c1ccc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1.Nc1ncc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1
• InChI: InChI=1S/C23H23BrN6O2.C20H13BrClF3N4.2C19H14BrClN4.C18H14BrClN6.C18H13BrClN5.C18H14BrN5.C17H12BrClN4S/c1-23(2,3)32-22(31)29-20-10-17(27-14-28-20)11-25-18-9-16(15-7-5-4-6-8-15)13-30-19(24)12-26-21(18)30;21-18-10-28-19-16(26-8-12-5-6-17(27-9-12)20(23,24)25)7-13(11-29(18)19)14-3-1-2-4-15(14)22;20-18-11-24-19-17(23-10-13-4-3-7-22-9-13)8-14(12-25(18)19)15-5-1-2-6-16(15)21;20-18-11-24-19-17(23-10-13-5-7-22-8-6-13)9-14(12-25(18)19)15-3-1-2-4-16(15)21;19-16-9-23-17-15(22-6-11-7-24-18(21)25-8-11)5-12(10-26(16)17)13-3-1-2-4-14(13)20;19-17-9-24-18-16(23-8-12-6-21-11-22-7-12)5-13(10-25(17)18)14-3-1-2-4-15(14)20;19-17-10-23-18-16(22-9-13-7-20-12-21-8-13)6-15(11-24(17)18)14-4-2-1-3-5-14;18-15-8-22-17-14(21-9-16-20-5-6-24-16)7-11(10-23(15)17)12-3-1-2-4-13(12)19/h4-10,12-14,25H,11H2,1-3H3,(H,27,28,29,31);1-7,9-11,26H,8H2;2*1-9,11-12,23H,10H2;1-5,7-10,22H,6H2,(H2,21,24,25);1-7,9-11,23H,8H2;1-8,10-12,22H,9H2;1-8,10,21H,9H2
• InChIKey: NGPNLCHOPLQRSM-UHFFFAOYSA-N
• XLogP: 41.68
• TPSA: 453.67 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 40
• Rotatable Bonds: 33
• Heavy Atoms: 210
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3448.88
LogP ≤ 5	41.68
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	40

Frequently Asked Questions

What is the IUPAC name of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate?

The IUPAC name of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate (CID 159774927) is N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate.

What is the SMILES notation for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate?

The canonical SMILES for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate is Brc1cnc2c(NCc3cncnc3)cc(-c3ccccc3)cn12.CC(C)(C)OC(=O)Nc1cc(CNc2cc(-c3ccccc3)cn3c(Br)cnc23)ncn1.Clc1ccccc1-c1cc(NCc2cccnc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2ccncc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2cncnc2)c2ncc(Br)n2c1.Clc1ccccc1-c1cc(NCc2nccs2)c2ncc(Br)n2c1.FC(F)(F)c1ccc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1.Nc1ncc(CNc2cc(-c3ccccc3Cl)cn3c(Br)cnc23)cn1.

What is the InChIKey of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate?

The InChIKey is NGPNLCHOPLQRSM-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H23BrN6O2.C20H13BrClF3N4.2C19H14BrClN4.C18H14BrClN6.C18H13BrClN5.C18H14BrN5.C17H12BrClN4S/c1-23(2,3)32-22(31)29-20-10-17(27-14-28-20)11-25-18-9-16(15-7-5-4-6-8-15)13-30-19(24)12-26-21(18)30;21-18-10-28-19-16(26-8-12-5-6-17(27-9-12)20(23,24)25)7-13(11-29(18)19)14-3-1-2-4-15(14)22;20-18-11-24-19-17(23-10-13-4-3-7-22-9-13)8-14(12-25(18)19)15-5-1-2-6-16(15)21;20-18-11-24-19-17(23-10-13-5-7-22-8-6-13)9-14(12-25(18)19)15-3-1-2-4-16(15)21;19-16-9-23-17-15(22-6-11-7-24-18(21)25-8-11)5-12(10-26(16)17)13-3-1-2-4-14(13)20;19-17-9-24-18-16(23-8-12-6-21-11-22-7-12)5-13(10-25(17)18)14-3-1-2-4-15(14)20;19-17-10-23-18-16(22-9-13-7-20-12-21-8-13)6-15(11-24(17)18)14-4-2-1-3-5-14;18-15-8-22-17-14(21-9-16-20-5-6-24-16)7-11(10-23(15)17)12-3-1-2-4-13(12)19/h4-10,12-14,25H,11H2,1-3H3,(H,27,28,29,31);1-7,9-11,26H,8H2;2*1-9,11-12,23H,10H2;1-5,7-10,22H,6H2,(H2,21,24,25);1-7,9-11,23H,8H2;1-8,10-12,22H,9H2;1-8,10,21H,9H2.

What are the key properties of N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate?

N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate has a molecular weight of 3448.88 g/mol, XLogP of 41.68, 33 rotatable bonds, 10 hydrogen bond donors, and 40 hydrogen bond acceptors.

Where does this data come from?

All data for N-[(2-aminopyrimidin-5-yl)methyl]-3-bromo-6-(2-chlorophenyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-(1,3-thiazol-2-ylmethyl)imidazo[1,2-a]pyridin-8-amine;3-bromo-6-(2-chlorophenyl)-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]imidazo[1,2-a]pyridin-8-amine;3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine;tert-butyl N-[6-[[(3-bromo-6-phenylimidazo[1,2-a]pyridin-8-yl)amino]methyl]pyrimidin-4-yl]carbamate is sourced from PubChem (CID 159774927), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).