5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one

C93H61F3N26O12S6 — CID 159776661

About 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one

5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one (PubChem CID 159776661) has the molecular formula C93H61F3N26O12S6 and a molecular weight of 1984.08 g/mol. Its IUPAC name is 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one.

Molecular Properties

• Compound Name: 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one
• PubChem CID: 159776661
• Molecular Formula: C93H61F3N26O12S6
• Molecular Weight: 1984.08 g/mol
• Exact Mass: 1982.32
• IUPAC Name: 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one
• SMILES: Cc1cccc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.Cc1cncc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.N#Cc1cccc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.O=C1C=C(n2ncc3c(-c4ccncc4)cccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4ccc(F)cn4)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cccc(C(F)F)n4)ccc32)S(=O)N1
• InChI: InChI=1S/C16H10F2N4O2S.C16H9N5O2S.C16H12N4O2S.C15H9FN4O2S.C15H11N5O2S.C15H10N4O2S/c17-16(18)12-3-1-2-11(20-12)9-4-5-13-10(6-9)8-19-22(13)15-7-14(23)21-25(15)24;17-8-12-2-1-3-13(19-12)10-4-5-14-11(6-10)9-18-21(14)16-7-15(22)20-24(16)23;1-10-3-2-4-13(18-10)11-5-6-14-12(7-11)9-17-20(14)16-8-15(21)19-23(16)22;16-11-2-3-12(17-8-11)9-1-4-13-10(5-9)7-18-20(13)15-6-14(21)19-23(15)22;1-9-6-16-8-12(18-9)10-2-3-13-11(4-10)7-17-20(13)15-5-14(21)19-23(15)22;20-14-8-15(22(21)18-14)19-13-3-1-2-11(12(13)9-17-19)10-4-6-16-7-5-10/h1-8,16H,(H,21,23);1-7,9H,(H,20,22);2-9H,1H3,(H,19,21);1-8H,(H,19,21);2-8H,1H3,(H,19,21);1-9H,(H,18,20)
• InChIKey: NGVGMQBCYDUIHJ-UHFFFAOYSA-N
• XLogP: 11.10
• TPSA: 497.96 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 32
• Rotatable Bonds: 13
• Heavy Atoms: 140
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1984.08
LogP ≤ 5	11.10
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	32

Frequently Asked Questions

What is the IUPAC name of 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one?

The IUPAC name of 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one (CID 159776661) is 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one.

What is the SMILES notation for 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one?

The canonical SMILES for 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one is Cc1cccc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.Cc1cncc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.N#Cc1cccc(-c2ccc3c(cnn3C3=CC(=O)NS3=O)c2)n1.O=C1C=C(n2ncc3c(-c4ccncc4)cccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4ccc(F)cn4)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cccc(C(F)F)n4)ccc32)S(=O)N1.

What is the InChIKey of 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one?

The InChIKey is NGVGMQBCYDUIHJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C16H10F2N4O2S.C16H9N5O2S.C16H12N4O2S.C15H9FN4O2S.C15H11N5O2S.C15H10N4O2S/c17-16(18)12-3-1-2-11(20-12)9-4-5-13-10(6-9)8-19-22(13)15-7-14(23)21-25(15)24;17-8-12-2-1-3-13(19-12)10-4-5-14-11(6-10)9-18-21(14)16-7-15(22)20-24(16)23;1-10-3-2-4-13(18-10)11-5-6-14-12(7-11)9-17-20(14)16-8-15(21)19-23(16)22;16-11-2-3-12(17-8-11)9-1-4-13-10(5-9)7-18-20(13)15-6-14(21)19-23(15)22;1-9-6-16-8-12(18-9)10-2-3-13-11(4-10)7-17-20(13)15-5-14(21)19-23(15)22;20-14-8-15(22(21)18-14)19-13-3-1-2-11(12(13)9-17-19)10-4-6-16-7-5-10/h1-8,16H,(H,21,23);1-7,9H,(H,20,22);2-9H,1H3,(H,19,21);1-8H,(H,19,21);2-8H,1H3,(H,19,21);1-9H,(H,18,20).

What are the key properties of 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one?

5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one has a molecular weight of 1984.08 g/mol, XLogP of 11.10, 13 rotatable bonds, 6 hydrogen bond donors, and 32 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[6-(difluoromethyl)-2-pyridinyl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]pyridine-2-carbonitrile;5-[5-(5-fluoro-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methylpyrazin-2-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(6-methyl-2-pyridinyl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;1-oxo-5-(4-pyridin-4-ylindazol-1-yl)-1,2-thiazol-3-one is sourced from PubChem (CID 159776661), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).