3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine

C94H102F17N25O10 — CID 159778555

About 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine

3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine (PubChem CID 159778555) has the molecular formula C94H102F17N25O10 and a molecular weight of 2064.98 g/mol. Its IUPAC name is 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine.

Molecular Properties

• Compound Name: 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine
• PubChem CID: 159778555
• Molecular Formula: C94H102F17N25O10
• Molecular Weight: 2064.98 g/mol
• Exact Mass: 2063.80
• IUPAC Name: 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine
• SMILES: CCOC(C)(C)c1nnc2cnc(-c3ccc(OC(C)(C)C(F)(F)F)nc3)cn12.CCOC(C)(C)c1nnc2cnc(-c3cnc(OC(C)(C)C(F)(F)F)c(F)c3)cn12.COC(C)(C)c1nnc2cnc(-c3ccc(OC(C)(C)C(F)(F)F)nc3)cn12.COC(C)(C)c1nnc2cnc(-c3ccc(OC4(C(F)(F)F)CCC4)nc3)cn12.COC(C)(C)c1nnc2cnc(-c3cnc(OC4(C(F)(F)F)CCC4)c(F)c3)cn12
• InChI: InChI=1S/C19H19F4N5O2.C19H21F4N5O2.C19H20F3N5O2.C19H22F3N5O2.C18H20F3N5O2/c1-17(2,29-3)16-27-26-14-9-24-13(10-28(14)16)11-7-12(20)15(25-8-11)30-18(5-4-6-18)19(21,22)23;1-6-29-17(2,3)16-27-26-14-9-24-13(10-28(14)16)11-7-12(20)15(25-8-11)30-18(4,5)19(21,22)23;1-17(2,28-3)16-26-25-14-10-23-13(11-27(14)16)12-5-6-15(24-9-12)29-18(7-4-8-18)19(20,21)22;1-6-28-17(2,3)16-26-25-14-10-23-13(11-27(14)16)12-7-8-15(24-9-12)29-18(4,5)19(20,21)22;1-16(2,27-5)15-25-24-13-9-22-12(10-26(13)15)11-6-7-14(23-8-11)28-17(3,4)18(19,20)21/h7-10H,4-6H2,1-3H3;7-10H,6H2,1-5H3;5-6,9-11H,4,7-8H2,1-3H3;7-11H,6H2,1-5H3;6-10H,1-5H3
• InChIKey: NHBFCZFRFWPCJY-UHFFFAOYSA-N
• XLogP: 20.28
• TPSA: 372.15 Ų
• H-Bond Acceptors: 35
• Rotatable Bonds: 27
• Heavy Atoms: 146
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2064.98
LogP ≤ 5	20.28
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The IUPAC name of 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine (CID 159778555) is 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine.

What is the SMILES notation for 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The canonical SMILES for 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine is CCOC(C)(C)c1nnc2cnc(-c3ccc(OC(C)(C)C(F)(F)F)nc3)cn12.CCOC(C)(C)c1nnc2cnc(-c3cnc(OC(C)(C)C(F)(F)F)c(F)c3)cn12.COC(C)(C)c1nnc2cnc(-c3ccc(OC(C)(C)C(F)(F)F)nc3)cn12.COC(C)(C)c1nnc2cnc(-c3ccc(OC4(C(F)(F)F)CCC4)nc3)cn12.COC(C)(C)c1nnc2cnc(-c3cnc(OC4(C(F)(F)F)CCC4)c(F)c3)cn12.

What is the InChIKey of 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine?

The InChIKey is NHBFCZFRFWPCJY-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H19F4N5O2.C19H21F4N5O2.C19H20F3N5O2.C19H22F3N5O2.C18H20F3N5O2/c1-17(2,29-3)16-27-26-14-9-24-13(10-28(14)16)11-7-12(20)15(25-8-11)30-18(5-4-6-18)19(21,22)23;1-6-29-17(2,3)16-27-26-14-9-24-13(10-28(14)16)11-7-12(20)15(25-8-11)30-18(4,5)19(21,22)23;1-17(2,28-3)16-26-25-14-10-23-13(11-27(14)16)12-5-6-15(24-9-12)29-18(7-4-8-18)19(20,21)22;1-6-28-17(2,3)16-26-25-14-10-23-13(11-27(14)16)12-7-8-15(24-9-12)29-18(4,5)19(20,21)22;1-16(2,27-5)15-25-24-13-9-22-12(10-26(13)15)11-6-7-14(23-8-11)28-17(3,4)18(19,20)21/h7-10H,4-6H2,1-3H3;7-10H,6H2,1-5H3;5-6,9-11H,4,7-8H2,1-3H3;7-11H,6H2,1-5H3;6-10H,1-5H3.

What are the key properties of 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine?

3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine has a molecular weight of 2064.98 g/mol, XLogP of 20.28, 27 rotatable bonds, 0 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 3-(2-ethoxypropan-2-yl)-6-[5-fluoro-6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-ethoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[5-fluoro-6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-3-(2-methoxypropan-2-yl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-[1-(trifluoromethyl)cyclobutyl]oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-methoxypropan-2-yl)-6-[6-(1,1,1-trifluoro-2-methylpropan-2-yl)oxy-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine is sourced from PubChem (CID 159778555), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).