4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one

C131H158F5N29O17 — CID 159780706

IUPAC4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one
SMILESCC(C)(O)c1cc(-c2ccc(F)cc2)nn2cc(C(=O)N3CCNC(=O)C3(C)C)nc12.CC(C)[C@@H](O)C(=O)N1CCN(C(=O)c2cn3nc(-c4ccc(F)cc4)cc(N4C[C@@H](C)O[C@@H](C)C4)c3n2)C(C)(C)C1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCN(C(=O)C(C)(C)O)CC4(C)C)nc23)C[C@H](C)O1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1.C[C@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1
InChIInChI=1S/C30H39FN6O4.C29H37FN6O4.2C25H29FN6O3.C22H24FN5O3/c1-18(2)26(38)29(40)34-11-12-36(30(5,6)17-34)28(39)24-16-37-27(32-24)25(35-14-19(3)41-20(4)15-35)13-23(33-37)21-7-9-22(31)10-8-21;1-18-14-34(15-19(2)40-18)24-13-22(20-7-9-21(30)10-8-20)32-36-16-23(31-25(24)36)26(37)35-12-11-33(17-28(35,3)4)27(38)29(5,6)39;2*1-15-12-30(13-16(2)35-15)21-11-19(17-5-7-18(26)8-6-17)29-32-14-20(28-22(21)32)23(33)31-10-9-27-24(34)25(31,3)4;1-21(2)20(30)24-9-10-27(21)19(29)17-12-28-18(25-17)15(22(3,4)31)11-16(26-28)13-5-7-14(23)8-6-13/h7-10,13,16,18-20,26,38H,11-12,14-15,17H2,1-6H3;7-10,13,16,18-19,39H,11-12,14-15,17H2,1-6H3;2*5-8,11,14-16H,9-10,12-13H2,1-4H3,(H,27,34);5-8,11-12,31H,9-10H2,1-4H3,(H,24,30)/t19-,20+,26-;18-,19+;15-,16+;15-,16-;/m1..0./s1
InChIKeyNHIBEUXVILRZJO-WENNPJFCSA-N
MW2505.88 g/mol
LogP13.32
Rot. Bonds18

About 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one

4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one (PubChem CID 159780706) has the molecular formula C131H158F5N29O17 and a molecular weight of 2505.88 g/mol. Its IUPAC name is 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one.

Molecular Properties

Compound Name4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one
PubChem CID159780706
Molecular FormulaC131H158F5N29O17
Molecular Weight2505.88 g/mol
Exact Mass2504.23
IUPAC Name4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one
SMILESCC(C)(O)c1cc(-c2ccc(F)cc2)nn2cc(C(=O)N3CCNC(=O)C3(C)C)nc12.CC(C)[C@@H](O)C(=O)N1CCN(C(=O)c2cn3nc(-c4ccc(F)cc4)cc(N4C[C@@H](C)O[C@@H](C)C4)c3n2)C(C)(C)C1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCN(C(=O)C(C)(C)O)CC4(C)C)nc23)C[C@H](C)O1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1.C[C@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1
InChIInChI=1S/C30H39FN6O4.C29H37FN6O4.2C25H29FN6O3.C22H24FN5O3/c1-18(2)26(38)29(40)34-11-12-36(30(5,6)17-34)28(39)24-16-37-27(32-24)25(35-14-19(3)41-20(4)15-35)13-23(33-37)21-7-9-22(31)10-8-21;1-18-14-34(15-19(2)40-18)24-13-22(20-7-9-21(30)10-8-20)32-36-16-23(31-25(24)36)26(37)35-12-11-33(17-28(35,3)4)27(38)29(5,6)39;2*1-15-12-30(13-16(2)35-15)21-11-19(17-5-7-18(26)8-6-17)29-32-14-20(28-22(21)32)23(33)31-10-9-27-24(34)25(31,3)4;1-21(2)20(30)24-9-10-27(21)19(29)17-12-28-18(25-17)15(22(3,4)31)11-16(26-28)13-5-7-14(23)8-6-13/h7-10,13,16,18-20,26,38H,11-12,14-15,17H2,1-6H3;7-10,13,16,18-19,39H,11-12,14-15,17H2,1-6H3;2*5-8,11,14-16H,9-10,12-13H2,1-4H3,(H,27,34);5-8,11-12,31H,9-10H2,1-4H3,(H,24,30)/t19-,20+,26-;18-,19+;15-,16+;15-,16-;/m1..0./s1
InChIKeyNHIBEUXVILRZJO-WENNPJFCSA-N
XLogP13.32
TPSA490.99 Ų
H-Bond Donors6
H-Bond Acceptors36
Rotatable Bonds18
Heavy Atoms182
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002505.88
LogP ≤ 513.32
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1036

Analyze 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperidin-4-one;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-(4-hydroxy-3-methylpiperidin-1-yl)methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[3-(2-hydroxypropan-2-yl)piperidin-1-yl]methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[(2S)-2-methylpiperidin-1-yl]methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-(2-pyridin-4-ylpiperidin-1-yl)methanone;methyl (3R,4R)-1-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3-methylpiperidine-4-carboxylate
CID 157063737
(2R)-1-[(2S)-4-[6-(4-fluorophenyl)-8-methylimidazo[1,2-b]pyridazine-2-carbonyl]-2-methylpiperazin-1-yl]-2-hydroxy-4-methylpentan-1-one;methyl (3R,4R)-1-[6-(4-fluorophenyl)-8-methylimidazo[1,2-b]pyridazine-2-carbonyl]-3-methylpiperidine-4-carboxylate;pyridin-2-ylmethyl (2S)-4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]-2-methylpiperazine-1-carboxylate;pyridin-3-ylmethyl (2S)-4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]-2-methylpiperazine-1-carboxylate
CID 157105523
7-[2-(3-cyclopropylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;1-[6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]imidazo[1,2-a]pyridin-3-yl]ethanol;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-N-(oxan-4-yl)imidazo[1,2-a]pyridine-3-carboxamide;7-[2-(3-methylphenyl)-3-pyridinyl]imidazo[1,5-a]pyridine;7-[2-[3-(trifluoromethyl)phenyl]-3-pyridinyl]imidazo[1,5-a]pyridine
CID 157129590
[4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-(2-methyl-1H-imidazol-5-yl)methanone;4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2H-pyrrol-4-yl)piperazin-2-one;[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]-[2,2-dimethyl-4-(5-methyl-1H-imidazole-4-carbonyl)piperazin-1-yl]methanone;3,3,3-trifluoro-1-[4-[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one
CID 157134662
1-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperidin-4-one;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-(4-hydroxy-3-methylpiperidin-1-yl)methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[3-(2-hydroxypropan-2-yl)piperidin-1-yl]methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[(2S)-2-methylpiperidin-1-yl]methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-(2-pyridin-4-ylpiperidin-1-yl)methanone
CID 157135017
4-[8-Tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(2-methyltetrazol-5-yl)piperazin-2-one;1-[4-[6-(3-fluoro-4-methylphenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;1-[4-[6-(3-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;1-[4-[6-[3-fluoro-4-(trifluoromethyl)phenyl]-8-propan-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one
CID 157145622
6-cyclopropyl-N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-2-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide;6-cyclopropyl-N-[3-hydroxy-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide;N-[3-hydroxy-3-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]oxan-4-yl]-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide
CID 157207969
8-ethyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carboxylic acid;[8-ethyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]-[(3S)-3-methylpiperazin-1-yl]methanone;6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carboxylic acid;[6-(4-fluorophenyl)-8-methylimidazo[1,2-b]pyridazin-2-yl]-[(3S)-3-methylpiperazin-1-yl]methanone;[6-(4-fluorophenyl)-8-propan-2-ylimidazo[1,2-b]pyridazin-2-yl]-[(3S)-3-methylpiperazin-1-yl]methanone;[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazin-2-yl]-[(3S)-3-methylpiperazin-1-yl]methanone
CID 157210328
tert-butyl 4-[8-[(2R,6S)-2,6-dimethyloxan-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazine-1-carboxylate;4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-(oxetan-3-yl)piperazin-2-one;4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-1-ethyl-3,3-dimethylpiperazin-2-one;[4-[8-[(2R,6S)-2,6-dimethyloxan-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-[3-hydroxy-3-(trifluoromethyl)cyclobutyl]methanone;4-[6-(4-fluorophenyl)-8-prop-1-en-2-ylimidazo[1,2-b]pyridazine-2-carbonyl]-1,3,3-trimethylpiperazin-2-one
CID 157211560
(3S,4R)-1-[2-[(2S)-1-(2,4-difluorobenzoyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-(3,4-difluoro-2-methylbenzoyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-4-hydroxy-1-[2-[(2S)-1-(1H-indole-7-carbonyl)piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidine-3-carbonitrile;(3S,4R)-1-[2-[(2S)-1-[6-(hydroxymethyl)pyridine-2-carbonyl]piperidin-2-yl]-6-methylpyrazolo[1,5-a]pyrimidin-5-yl]-4-methylpyrrolidine-3-carbonitrile;(3S,4R)-4-methyl-1-[6-methyl-2-[(2S)-1-[6-(trifluoromethyl)pyridine-2-carbonyl]piperidin-2-yl]pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolidine-3-carbonitrile
CID 157314601
benzyl 4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperazine-1-carboxylate;tert-butyl 2-[4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperazin-1-yl]acetate;ethyl 4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperazine-1-carboxylate;(2R)-1-[4-[6-(4-fluorophenyl)-8-(trifluoromethyl)imidazo[1,2-b]pyridazine-2-carbonyl]piperazin-1-yl]-2-hydroxy-4,4-dimethylpentan-1-one
CID 157320275
4-[8-Tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-1-cyclopropyl-3,3-dimethylpiperazin-2-one;4-[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethyl-1-propan-2-ylpiperazin-2-one;[8-tert-butyl-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]-(2,2-dimethylpiperazin-1-yl)methanone;[4-[6-(4-fluorophenyl)-8-(oxan-4-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-[3-hydroxy-3-(trifluoromethyl)cyclobutyl]methanone
CID 157384753

Frequently Asked Questions

What is the IUPAC name of 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one?
The IUPAC name of 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one (CID 159780706) is 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one.
What is the SMILES notation for 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one?
The canonical SMILES for 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one is CC(C)(O)c1cc(-c2ccc(F)cc2)nn2cc(C(=O)N3CCNC(=O)C3(C)C)nc12.CC(C)[C@@H](O)C(=O)N1CCN(C(=O)c2cn3nc(-c4ccc(F)cc4)cc(N4C[C@@H](C)O[C@@H](C)C4)c3n2)C(C)(C)C1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCN(C(=O)C(C)(C)O)CC4(C)C)nc23)C[C@H](C)O1.C[C@@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1.C[C@H]1CN(c2cc(-c3ccc(F)cc3)nn3cc(C(=O)N4CCNC(=O)C4(C)C)nc23)C[C@H](C)O1.
What is the InChIKey of 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one?
The InChIKey is NHIBEUXVILRZJO-WENNPJFCSA-N. The full InChI is InChI=1S/C30H39FN6O4.C29H37FN6O4.2C25H29FN6O3.C22H24FN5O3/c1-18(2)26(38)29(40)34-11-12-36(30(5,6)17-34)28(39)24-16-37-27(32-24)25(35-14-19(3)41-20(4)15-35)13-23(33-37)21-7-9-22(31)10-8-21;1-18-14-34(15-19(2)40-18)24-13-22(20-7-9-21(30)10-8-20)32-36-16-23(31-25(24)36)26(37)35-12-11-33(17-28(35,3)4)27(38)29(5,6)39;2*1-15-12-30(13-16(2)35-15)21-11-19(17-5-7-18(26)8-6-17)29-32-14-20(28-22(21)32)23(33)31-10-9-27-24(34)25(31,3)4;1-21(2)20(30)24-9-10-27(21)19(29)17-12-28-18(25-17)15(22(3,4)31)11-16(26-28)13-5-7-14(23)8-6-13/h7-10,13,16,18-20,26,38H,11-12,14-15,17H2,1-6H3;7-10,13,16,18-19,39H,11-12,14-15,17H2,1-6H3;2*5-8,11,14-16H,9-10,12-13H2,1-4H3,(H,27,34);5-8,11-12,31H,9-10H2,1-4H3,(H,24,30)/t19-,20+,26-;18-,19+;15-,16+;15-,16-;/m1..0./s1.
What are the key properties of 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one?
4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one has a molecular weight of 2505.88 g/mol, XLogP of 13.32, 18 rotatable bonds, 6 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[8-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;4-[8-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one;(2R)-1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-3-methylbutan-1-one;1-[4-[8-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-1-yl]-2-hydroxy-2-methylpropan-1-one;4-[6-(4-fluorophenyl)-8-(2-hydroxypropan-2-yl)imidazo[1,2-b]pyridazine-2-carbonyl]-3,3-dimethylpiperazin-2-one is sourced from PubChem (CID 159780706), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).