N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

C143H134FN29O13S6 — CID 159780855

About N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide

N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (PubChem CID 159780855) has the molecular formula C143H134FN29O13S6 and a molecular weight of 2678.23 g/mol. Its IUPAC name is N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

Molecular Properties

• Compound Name: N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• PubChem CID: 159780855
• Molecular Formula: C143H134FN29O13S6
• Molecular Weight: 2678.23 g/mol
• Exact Mass: 2675.90
• IUPAC Name: N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide
• SMILES: CC(C)CC(=O)c1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc(CN(C)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc(CN(CCN(C)C)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc([C@@H](C)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc([C@@H](CO)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.C[C@@H](NC(=O)c1cc(-c2ccncc2)n[nH]1)c1cccc(F)c1.Cc1cccc([C@@H](C)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1
• InChI: InChI=1S/C23H25N5O2S.C23H22N4O2S.C20H18N4O3S.2C20H18N4O2S.C20H18N4OS.C17H15FN4O/c1-27(2)9-10-28(15-16-5-4-6-19(11-16)30-3)23(29)21-12-17-7-8-20(26-22(17)31-21)18-13-24-25-14-18;1-14(2)8-20(28)16-5-3-4-15(9-16)11-24-22(29)21-10-17-6-7-19(27-23(17)30-21)18-12-25-26-13-18;1-27-15-4-2-3-12(7-15)17(11-25)23-19(26)18-8-13-5-6-16(24-20(13)28-18)14-9-21-22-10-14;1-24(12-13-4-3-5-16(8-13)26-2)20(25)18-9-14-6-7-17(23-19(14)27-18)15-10-21-22-11-15;1-12(13-4-3-5-16(8-13)26-2)23-19(25)18-9-14-6-7-17(24-20(14)27-18)15-10-21-22-11-15;1-12-4-3-5-14(8-12)13(2)23-19(25)18-9-15-6-7-17(24-20(15)26-18)16-10-21-22-11-16;1-11(13-3-2-4-14(18)9-13)20-17(23)16-10-15(21-22-16)12-5-7-19-8-6-12/h4-8,11-14H,9-10,15H2,1-3H3,(H,24,25);3-7,9-10,12-14H,8,11H2,1-2H3,(H,24,29)(H,25,26);2-10,17,25H,11H2,1H3,(H,21,22)(H,23,26);3-11H,12H2,1-2H3,(H,21,22);3-12H,1-2H3,(H,21,22)(H,23,25);3-11,13H,1-2H3,(H,21,22)(H,23,25);2-11H,1H3,(H,20,23)(H,21,22)/t;;17-;;12-;13-;11-/m..1.111/s1
• InChIKey: NHIOIKCJTJCQGN-QPPIJZTBSA-N
• XLogP: 27.64
• TPSA: 554.57 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 34
• Rotatable Bonds: 39
• Heavy Atoms: 192
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2678.23
LogP ≤ 5	27.64
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	34

Frequently Asked Questions

What is the IUPAC name of N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The IUPAC name of N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CID 159780855) is N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide.

What is the SMILES notation for N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The canonical SMILES for N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is CC(C)CC(=O)c1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc(CN(C)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc(CN(CCN(C)C)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc([C@@H](C)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.COc1cccc([C@@H](CO)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.C[C@@H](NC(=O)c1cc(-c2ccncc2)n[nH]1)c1cccc(F)c1.Cc1cccc([C@@H](C)NC(=O)c2cc3ccc(-c4cn[nH]c4)nc3s2)c1.

What is the InChIKey of N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

The InChIKey is NHIOIKCJTJCQGN-QPPIJZTBSA-N. The full InChI is InChI=1S/C23H25N5O2S.C23H22N4O2S.C20H18N4O3S.2C20H18N4O2S.C20H18N4OS.C17H15FN4O/c1-27(2)9-10-28(15-16-5-4-6-19(11-16)30-3)23(29)21-12-17-7-8-20(26-22(17)31-21)18-13-24-25-14-18;1-14(2)8-20(28)16-5-3-4-15(9-16)11-24-22(29)21-10-17-6-7-19(27-23(17)30-21)18-12-25-26-13-18;1-27-15-4-2-3-12(7-15)17(11-25)23-19(26)18-8-13-5-6-16(24-20(13)28-18)14-9-21-22-10-14;1-24(12-13-4-3-5-16(8-13)26-2)20(25)18-9-14-6-7-17(23-19(14)27-18)15-10-21-22-11-15;1-12(13-4-3-5-16(8-13)26-2)23-19(25)18-9-14-6-7-17(24-20(14)27-18)15-10-21-22-11-15;1-12-4-3-5-14(8-12)13(2)23-19(25)18-9-15-6-7-17(24-20(15)26-18)16-10-21-22-11-16;1-11(13-3-2-4-14(18)9-13)20-17(23)16-10-15(21-22-16)12-5-7-19-8-6-12/h4-8,11-14H,9-10,15H2,1-3H3,(H,24,25);3-7,9-10,12-14H,8,11H2,1-2H3,(H,24,29)(H,25,26);2-10,17,25H,11H2,1H3,(H,21,22)(H,23,26);3-11H,12H2,1-2H3,(H,21,22);3-12H,1-2H3,(H,21,22)(H,23,25);3-11,13H,1-2H3,(H,21,22)(H,23,25);2-11H,1H3,(H,20,23)(H,21,22)/t;;17-;;12-;13-;11-/m..1.111/s1.

What are the key properties of N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide?

N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide has a molecular weight of 2678.23 g/mol, XLogP of 27.64, 39 rotatable bonds, 13 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for N-[2-(dimethylamino)ethyl]-N-[(3-methoxyphenyl)methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-fluorophenyl)ethyl]-3-pyridin-4-yl-1H-pyrazole-5-carboxamide;N-[(1S)-2-hydroxy-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methoxyphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(3-methoxyphenyl)methyl]-N-methyl-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[[3-(3-methylbutanoyl)phenyl]methyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide;N-[(1R)-1-(3-methylphenyl)ethyl]-6-(1H-pyrazol-4-yl)thieno[2,3-b]pyridine-2-carboxamide is sourced from PubChem (CID 159780855), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).