N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide

C102H106F4N24O5 — CID 159796229

IUPACN-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide
SMILESCOc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1CN(C)C.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc(C4CN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@@H]4CCN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@H]4CCN(C)C4)cn23)c1
InChIInChI=1S/2C26H27FN6O.C25H27FN6O2.C25H25FN6O/c2*1-16-9-23(27)22(26(34)30-20-4-5-20)10-21(16)19-11-29-33(15-19)25-12-28-24-6-3-17(14-32(24)25)18-7-8-31(2)13-18;1-15-7-21(26)20(25(33)29-18-5-6-18)8-19(15)16-10-28-32(14-16)24-11-27-23-9-22(34-4)17(12-30(2)3)13-31(23)24;1-15-7-22(26)21(25(33)29-19-4-5-19)8-20(15)17-9-28-32(14-17)24-10-27-23-6-3-16(13-31(23)24)18-11-30(2)12-18/h2*3,6,9-12,14-15,18,20H,4-5,7-8,13H2,1-2H3,(H,30,34);7-11,13-14,18H,5-6,12H2,1-4H3,(H,29,33);3,6-10,13-14,18-19H,4-5,11-12H2,1-2H3,(H,29,33)/t2*18-;;/m10../s1
InChIKeyNJFBIDRVBHTCBB-PNEGYFAFSA-N
MW1824.12 g/mol
LogP15.04
Rot. Bonds22

About N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide

N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide (PubChem CID 159796229) has the molecular formula C102H106F4N24O5 and a molecular weight of 1824.12 g/mol. Its IUPAC name is N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide.

Molecular Properties

Compound NameN-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide
PubChem CID159796229
Molecular FormulaC102H106F4N24O5
Molecular Weight1824.12 g/mol
Exact Mass1822.87
IUPAC NameN-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide
SMILESCOc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1CN(C)C.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc(C4CN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@@H]4CCN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@H]4CCN(C)C4)cn23)c1
InChIInChI=1S/2C26H27FN6O.C25H27FN6O2.C25H25FN6O/c2*1-16-9-23(27)22(26(34)30-20-4-5-20)10-21(16)19-11-29-33(15-19)25-12-28-24-6-3-17(14-32(24)25)18-7-8-31(2)13-18;1-15-7-21(26)20(25(33)29-18-5-6-18)8-19(15)16-10-28-32(14-16)24-11-27-23-9-22(34-4)17(12-30(2)3)13-31(23)24;1-15-7-22(26)21(25(33)29-19-4-5-19)8-20(15)17-9-28-32(14-17)24-10-27-23-6-3-16(13-31(23)24)18-11-30(2)12-18/h2*3,6,9-12,14-15,18,20H,4-5,7-8,13H2,1-2H3,(H,30,34);7-11,13-14,18H,5-6,12H2,1-4H3,(H,29,33);3,6-10,13-14,18-19H,4-5,11-12H2,1-2H3,(H,29,33)/t2*18-;;/m10../s1
InChIKeyNJFBIDRVBHTCBB-PNEGYFAFSA-N
XLogP15.04
TPSA279.07 Ų
H-Bond Donors4
H-Bond Acceptors25
Rotatable Bonds22
Heavy Atoms135
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001824.12
LogP ≤ 515.04
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1025

Analyze N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide with MolForge

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Related Compounds

US10138241, Example 94
CID 134328409
US10138241, Example 101
CID 134328431
US10138241, Example 95
CID 134328445
US10138241, Example 96
CID 134328570
US10138241, Example 86
CID 134328486
Tert-butyl 4-[3-[4-[5-(cyclopropylcarbamoyl)-4-fluoro-2-methylphenyl]pyrazol-1-yl]-7-methoxyimidazo[1,2-a]pyridin-6-yl]-4-fluoropiperidine-1-carboxylate
CID 134328422
N-cyclopropyl-2-fluoro-5-[[1-[6-(4-fluoropiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]methyl]benzamide
CID 134328467
N-cyclopropyl-5-[1-[7-ethoxy-6-(4-fluoropiperidin-4-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide
CID 134328579
N-cyclopropyl-2-fluoro-5-[1-[6-(4-fluoropiperidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-4-methylbenzamide
CID 134338463
N-(2-cyclopropylethyl)-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide
CID 155015424
3-(8-amino-2-piperidin-3-ylimidazo[1,2-a]pyrazin-5-yl)-N,N-dimethylbenzamide;3-(8-amino-2-piperidin-3-ylimidazo[1,2-a]pyrazin-5-yl)-N-[(1S)-1-(4-methoxyphenyl)ethyl]benzamide;4-(8-amino-2-piperidin-3-ylimidazo[1,2-a]pyrazin-5-yl)-N-[(4-methoxyphenyl)methyl]benzamide;3-(8-amino-2-piperidin-3-ylimidazo[1,2-a]pyrazin-5-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]benzamide;3-(8-amino-2-piperidin-3-ylimidazo[1,2-a]pyrazin-5-yl)-N-[[4-(trifluoromethyl)phenyl]methyl]benzamide;3-(1-methylpyrazol-4-yl)-2-pyrrolidin-3-ylimidazo[1,2-a]pyrazin-8-amine
CID 158278593
CID 158865296
CID 158865296

Frequently Asked Questions

What is the IUPAC name of N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide?
The IUPAC name of N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide (CID 159796229) is N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide.
What is the SMILES notation for N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide?
The canonical SMILES for N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide is COc1cc2ncc(-n3cc(-c4cc(C(=O)NC5CC5)c(F)cc4C)cn3)n2cc1CN(C)C.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc(C4CN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@@H]4CCN(C)C4)cn23)c1.Cc1cc(F)c(C(=O)NC2CC2)cc1-c1cnn(-c2cnc3ccc([C@H]4CCN(C)C4)cn23)c1.
What is the InChIKey of N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide?
The InChIKey is NJFBIDRVBHTCBB-PNEGYFAFSA-N. The full InChI is InChI=1S/2C26H27FN6O.C25H27FN6O2.C25H25FN6O/c2*1-16-9-23(27)22(26(34)30-20-4-5-20)10-21(16)19-11-29-33(15-19)25-12-28-24-6-3-17(14-32(24)25)18-7-8-31(2)13-18;1-15-7-21(26)20(25(33)29-18-5-6-18)8-19(15)16-10-28-32(14-16)24-11-27-23-9-22(34-4)17(12-30(2)3)13-31(23)24;1-15-7-22(26)21(25(33)29-19-4-5-19)8-20(15)17-9-28-32(14-17)24-10-27-23-6-3-16(13-31(23)24)18-11-30(2)12-18/h2*3,6,9-12,14-15,18,20H,4-5,7-8,13H2,1-2H3,(H,30,34);7-11,13-14,18H,5-6,12H2,1-4H3,(H,29,33);3,6-10,13-14,18-19H,4-5,11-12H2,1-2H3,(H,29,33)/t2*18-;;/m10../s1.
What are the key properties of N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide?
N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide has a molecular weight of 1824.12 g/mol, XLogP of 15.04, 22 rotatable bonds, 4 hydrogen bond donors, and 25 hydrogen bond acceptors.
Where does this data come from?
All data for N-cyclopropyl-5-[1-[6-[(dimethylamino)methyl]-7-methoxyimidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]-2-fluoro-4-methylbenzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-(1-methylazetidin-3-yl)imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3S)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide;N-cyclopropyl-2-fluoro-4-methyl-5-[1-[6-[(3R)-1-methylpyrrolidin-3-yl]imidazo[1,2-a]pyridin-3-yl]pyrazol-4-yl]benzamide is sourced from PubChem (CID 159796229), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).