4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide

C141H156Cl3F7N18O6Si4 — CID 159801549

IUPAC4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide
SMILESC=C[Si](C)(C)c1ccc(NC(=O)N2CCN(c3ncccc3Cl)C[C@H]2C)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)C2=CCN(c3ncccc3Cl)CC2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3Cl)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3F)cc2)cc1
InChIInChI=1S/C28H32F3N3OSi.C27H32ClN3OSi.C26H35ClN4OSi.C21H27ClN4OSi.C20H15F3N2O.C19H15FN2O/c1-36(2,20-19-34-17-4-3-5-18-34)24-14-12-23(13-15-24)33-27(35)22-10-8-21(9-11-22)26-25(28(29,30)31)7-6-16-32-26;1-33(2,20-19-31-17-4-3-5-18-31)24-14-12-23(13-15-24)30-27(32)22-10-8-21(9-11-22)26-25(28)7-6-16-29-26;1-33(2,20-19-30-15-4-3-5-16-30)23-10-8-22(9-11-23)29-26(32)21-12-17-31(18-13-21)25-24(27)7-6-14-28-25;1-5-28(3,4)18-10-8-17(9-11-18)24-21(27)26-14-13-25(15-16(26)2)20-19(22)7-6-12-23-20;1-13-4-10-16(11-5-13)25-19(26)15-8-6-14(7-9-15)18-17(20(21,22)23)3-2-12-24-18;1-13-4-10-16(11-5-13)22-19(23)15-8-6-14(7-9-15)18-17(20)3-2-12-21-18/h6-16H,3-5,17-20H2,1-2H3,(H,33,35);6-16H,3-5,17-20H2,1-2H3,(H,30,32);6-12,14H,3-5,13,15-20H2,1-2H3,(H,29,32);5-12,16H,1,13-15H2,2-4H3,(H,24,27);2-12H,1H3,(H,25,26);2-12H,1H3,(H,22,23)/t;;;16-;;/m...1../s1
InChIKeyNJVXRZBCOKJXLF-WWPSXCDTSA-N
MW2550.61 g/mol
LogP31.28
Rot. Bonds31

About 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide

4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide (PubChem CID 159801549) has the molecular formula C141H156Cl3F7N18O6Si4 and a molecular weight of 2550.61 g/mol. Its IUPAC name is 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide.

Molecular Properties

Compound Name4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide
PubChem CID159801549
Molecular FormulaC141H156Cl3F7N18O6Si4
Molecular Weight2550.61 g/mol
Exact Mass2547.05
IUPAC Name4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide
SMILESC=C[Si](C)(C)c1ccc(NC(=O)N2CCN(c3ncccc3Cl)C[C@H]2C)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)C2=CCN(c3ncccc3Cl)CC2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3Cl)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3F)cc2)cc1
InChIInChI=1S/C28H32F3N3OSi.C27H32ClN3OSi.C26H35ClN4OSi.C21H27ClN4OSi.C20H15F3N2O.C19H15FN2O/c1-36(2,20-19-34-17-4-3-5-18-34)24-14-12-23(13-15-24)33-27(35)22-10-8-21(9-11-22)26-25(28(29,30)31)7-6-16-32-26;1-33(2,20-19-31-17-4-3-5-18-31)24-14-12-23(13-15-24)30-27(32)22-10-8-21(9-11-22)26-25(28)7-6-16-29-26;1-33(2,20-19-30-15-4-3-5-16-30)23-10-8-22(9-11-23)29-26(32)21-12-17-31(18-13-21)25-24(27)7-6-14-28-25;1-5-28(3,4)18-10-8-17(9-11-18)24-21(27)26-14-13-25(15-16(26)2)20-19(22)7-6-12-23-20;1-13-4-10-16(11-5-13)25-19(26)15-8-6-14(7-9-15)18-17(20(21,22)23)3-2-12-24-18;1-13-4-10-16(11-5-13)22-19(23)15-8-6-14(7-9-15)18-17(20)3-2-12-21-18/h6-16H,3-5,17-20H2,1-2H3,(H,33,35);6-16H,3-5,17-20H2,1-2H3,(H,30,32);6-12,14H,3-5,13,15-20H2,1-2H3,(H,29,32);5-12,16H,1,13-15H2,2-4H3,(H,24,27);2-12H,1H3,(H,25,26);2-12H,1H3,(H,22,23)/t;;;16-;;/m...1../s1
InChIKeyNJVXRZBCOKJXLF-WWPSXCDTSA-N
XLogP31.28
TPSA271.38 Ų
H-Bond Donors6
H-Bond Acceptors17
Rotatable Bonds31
Heavy Atoms179
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002550.61
LogP ≤ 531.28
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1017

Computed Properties (RDKit)

Structural Alerts{'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Analyze 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide?
The IUPAC name of 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide (CID 159801549) is 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide.
What is the SMILES notation for 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide?
The canonical SMILES for 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide is C=C[Si](C)(C)c1ccc(NC(=O)N2CCN(c3ncccc3Cl)C[C@H]2C)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)C2=CCN(c3ncccc3Cl)CC2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.C[Si](C)(CCN1CCCCC1)c1ccc(NC(=O)c2ccc(-c3ncccc3Cl)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1.Cc1ccc(NC(=O)c2ccc(-c3ncccc3F)cc2)cc1.
What is the InChIKey of 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide?
The InChIKey is NJVXRZBCOKJXLF-WWPSXCDTSA-N. The full InChI is InChI=1S/C28H32F3N3OSi.C27H32ClN3OSi.C26H35ClN4OSi.C21H27ClN4OSi.C20H15F3N2O.C19H15FN2O/c1-36(2,20-19-34-17-4-3-5-18-34)24-14-12-23(13-15-24)33-27(35)22-10-8-21(9-11-22)26-25(28(29,30)31)7-6-16-32-26;1-33(2,20-19-31-17-4-3-5-18-31)24-14-12-23(13-15-24)30-27(32)22-10-8-21(9-11-22)26-25(28)7-6-16-29-26;1-33(2,20-19-30-15-4-3-5-16-30)23-10-8-22(9-11-23)29-26(32)21-12-17-31(18-13-21)25-24(27)7-6-14-28-25;1-5-28(3,4)18-10-8-17(9-11-18)24-21(27)26-14-13-25(15-16(26)2)20-19(22)7-6-12-23-20;1-13-4-10-16(11-5-13)25-19(26)15-8-6-14(7-9-15)18-17(20(21,22)23)3-2-12-24-18;1-13-4-10-16(11-5-13)22-19(23)15-8-6-14(7-9-15)18-17(20)3-2-12-21-18/h6-16H,3-5,17-20H2,1-2H3,(H,33,35);6-16H,3-5,17-20H2,1-2H3,(H,30,32);6-12,14H,3-5,13,15-20H2,1-2H3,(H,29,32);5-12,16H,1,13-15H2,2-4H3,(H,24,27);2-12H,1H3,(H,25,26);2-12H,1H3,(H,22,23)/t;;;16-;;/m...1../s1.
What are the key properties of 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide?
4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide has a molecular weight of 2550.61 g/mol, XLogP of 31.28, 31 rotatable bonds, 6 hydrogen bond donors, and 17 hydrogen bond acceptors.
Where does this data come from?
All data for 4-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]benzamide;1-(3-chloro-2-pyridinyl)-N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide;(2R)-4-(3-chloro-2-pyridinyl)-N-[4-[ethenyl(dimethyl)silyl]phenyl]-2-methylpiperazine-1-carboxamide;N-[4-[dimethyl(2-piperidin-1-ylethyl)silyl]phenyl]-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide;4-(3-fluoro-2-pyridinyl)-N-(4-methylphenyl)benzamide;N-(4-methylphenyl)-4-[3-(trifluoromethyl)-2-pyridinyl]benzamide is sourced from PubChem (CID 159801549), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).