4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol

C107H135N17O10S3 — CID 159828666

About 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol

4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol (PubChem CID 159828666) has the molecular formula C107H135N17O10S3 and a molecular weight of 1915.57 g/mol. Its IUPAC name is 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol.

Molecular Properties

• Compound Name: 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol
• PubChem CID: 159828666
• Molecular Formula: C107H135N17O10S3
• Molecular Weight: 1915.57 g/mol
• Exact Mass: 1913.97
• IUPAC Name: 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol
• SMILES: CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(=O)N(C)C)cc3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)N)cc3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)O)cc3n2)cs1.Cc1ccc2c(OC(C)(C)C)cc(-c3cncc(C)n3)nc2c1.Cc1ccc2c(OC(C)(C)C)cc(-c3nccc(C)n3)nc2c1
• InChI: InChI=1S/C23H30N4O3S.C23H32N4O2S.C23H31N3O3S.2C19H21N3O/c1-14(2)24-22-26-19(13-31-22)18-11-20(30-23(3,4)5)16-9-8-15(10-17(16)25-18)29-12-21(28)27(6)7;1-14(2)25-21-27-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)26-18)28-13-23(6,7)24;1-14(2)24-21-26-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)25-18)28-13-23(6,7)27;1-12-6-7-14-15(8-12)22-16(9-18(14)23-19(3,4)5)17-11-20-10-13(2)21-17;1-12-6-7-14-15(10-12)22-16(11-17(14)23-19(3,4)5)18-20-9-8-13(2)21-18/h8-11,13-14H,12H2,1-7H3,(H,24,26);8-12,14H,13,24H2,1-7H3,(H,25,27);8-12,14,27H,13H2,1-7H3,(H,24,26);2*6-11H,1-5H3
• InChIKey: NNEBLWQOIYNPFZ-UHFFFAOYSA-N
• XLogP: 24.77
• TPSA: 331.17 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 29
• Rotatable Bonds: 25
• Heavy Atoms: 137
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1915.57
LogP ≤ 5	24.77
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The IUPAC name of 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol (CID 159828666) is 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol.

What is the SMILES notation for 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The canonical SMILES for 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol is CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(=O)N(C)C)cc3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)N)cc3n2)cs1.CC(C)Nc1nc(-c2cc(OC(C)(C)C)c3ccc(OCC(C)(C)O)cc3n2)cs1.Cc1ccc2c(OC(C)(C)C)cc(-c3cncc(C)n3)nc2c1.Cc1ccc2c(OC(C)(C)C)cc(-c3nccc(C)n3)nc2c1.

What is the InChIKey of 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

The InChIKey is NNEBLWQOIYNPFZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H30N4O3S.C23H32N4O2S.C23H31N3O3S.2C19H21N3O/c1-14(2)24-22-26-19(13-31-22)18-11-20(30-23(3,4)5)16-9-8-15(10-17(16)25-18)29-12-21(28)27(6)7;1-14(2)25-21-27-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)26-18)28-13-23(6,7)24;1-14(2)24-21-26-19(12-30-21)18-11-20(29-22(3,4)5)16-9-8-15(10-17(16)25-18)28-13-23(6,7)27;1-12-6-7-14-15(8-12)22-16(9-18(14)23-19(3,4)5)17-11-20-10-13(2)21-17;1-12-6-7-14-15(10-12)22-16(11-17(14)23-19(3,4)5)18-20-9-8-13(2)21-18/h8-11,13-14H,12H2,1-7H3,(H,24,26);8-12,14H,13,24H2,1-7H3,(H,25,27);8-12,14,27H,13H2,1-7H3,(H,24,26);2*6-11H,1-5H3.

What are the key properties of 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol?

4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol has a molecular weight of 1915.57 g/mol, XLogP of 24.77, 25 rotatable bonds, 5 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 4-[7-(2-amino-2-methylpropoxy)-4-[(2-methylpropan-2-yl)oxy]quinolin-2-yl]-N-propan-2-yl-1,3-thiazol-2-amine;N,N-dimethyl-2-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxyacetamide;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(6-methylpyrazin-2-yl)quinoline;7-methyl-4-[(2-methylpropan-2-yl)oxy]-2-(4-methylpyrimidin-2-yl)quinoline;2-methyl-1-[4-[(2-methylpropan-2-yl)oxy]-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-7-yl]oxypropan-2-ol is sourced from PubChem (CID 159828666), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).