(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

C117H145ClF4N28O7S — CID 159836120

IUPAC(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1c(Cl)nc2sccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2ccncn12.Cc1cc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1ccc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)n2ccnc12.Cc1nnc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccc12.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccc(F)cc21.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C(F)(F)F)c21
InChIInChI=1S/C18H21F3N4O.C18H22N4O.C18H23N3O.C17H21FN4O.C17H22N4O.C15H19N5O.C14H17ClN4OS/c1-17(2,23-16(26)13-10-7-22-8-11(10)13)15-9-5-4-6-12(18(19,20)21)14(9)25(3)24-15;1-10-11-6-4-5-7-12(11)16(22-21-10)18(2,3)20-17(23)15-13-8-19-9-14(13)15;1-11-8-14(15-6-4-5-7-21(11)15)18(2,3)20-17(22)16-12-9-19-10-13(12)16;1-17(2,20-16(23)14-11-7-19-8-12(11)14)15-10-5-4-9(18)6-13(10)22(3)21-15;1-10-4-5-13(21-7-6-19-15(10)21)17(2,3)20-16(22)14-11-8-18-9-12(11)14;1-15(2,14-18-5-9-3-4-16-8-20(9)14)19-13(21)12-10-6-17-7-11(10)12;1-14(2,10-11(15)17-13-19(10)3-4-21-13)18-12(20)9-7-5-16-6-8(7)9/h4-6,10-11,13,22H,7-8H2,1-3H3,(H,23,26);4-7,13-15,19H,8-9H2,1-3H3,(H,20,23);4-8,12-13,16,19H,9-10H2,1-3H3,(H,20,22);4-6,11-12,14,19H,7-8H2,1-3H3,(H,20,23);4-7,11-12,14,18H,8-9H2,1-3H3,(H,20,22);3-5,8,10-12,17H,6-7H2,1-2H3,(H,19,21);3-4,7-9,16H,5-6H2,1-2H3,(H,18,20)/t10-,11+,13?;13-,14+,15?;12-,13+,16?;2*11-,12+,14?;10-,11+,12?;7-,8+,9?
InChIKeyNOCDRVBGQNLRFR-ISEYYBFVSA-N
MW2199.15 g/mol
LogP11.63
Rot. Bonds21

About (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide

(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (PubChem CID 159836120) has the molecular formula C117H145ClF4N28O7S and a molecular weight of 2199.15 g/mol. Its IUPAC name is (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.

Molecular Properties

Compound Name(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
PubChem CID159836120
Molecular FormulaC117H145ClF4N28O7S
Molecular Weight2199.15 g/mol
Exact Mass2197.12
IUPAC Name(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
SMILESCC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1c(Cl)nc2sccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2ccncn12.Cc1cc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1ccc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)n2ccnc12.Cc1nnc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccc12.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccc(F)cc21.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C(F)(F)F)c21
InChIInChI=1S/C18H21F3N4O.C18H22N4O.C18H23N3O.C17H21FN4O.C17H22N4O.C15H19N5O.C14H17ClN4OS/c1-17(2,23-16(26)13-10-7-22-8-11(10)13)15-9-5-4-6-12(18(19,20)21)14(9)25(3)24-15;1-10-11-6-4-5-7-12(11)16(22-21-10)18(2,3)20-17(23)15-13-8-19-9-14(13)15;1-11-8-14(15-6-4-5-7-21(11)15)18(2,3)20-17(22)16-12-9-19-10-13(12)16;1-17(2,20-16(23)14-11-7-19-8-12(11)14)15-10-5-4-9(18)6-13(10)22(3)21-15;1-10-4-5-13(21-7-6-19-15(10)21)17(2,3)20-16(22)14-11-8-18-9-12(11)14;1-15(2,14-18-5-9-3-4-16-8-20(9)14)19-13(21)12-10-6-17-7-11(10)12;1-14(2,10-11(15)17-13-19(10)3-4-21-13)18-12(20)9-7-5-16-6-8(7)9/h4-6,10-11,13,22H,7-8H2,1-3H3,(H,23,26);4-7,13-15,19H,8-9H2,1-3H3,(H,20,23);4-8,12-13,16,19H,9-10H2,1-3H3,(H,20,22);4-6,11-12,14,19H,7-8H2,1-3H3,(H,20,23);4-7,11-12,14,18H,8-9H2,1-3H3,(H,20,22);3-5,8,10-12,17H,6-7H2,1-2H3,(H,19,21);3-4,7-9,16H,5-6H2,1-2H3,(H,18,20)/t10-,11+,13?;13-,14+,15?;12-,13+,16?;2*11-,12+,14?;10-,11+,12?;7-,8+,9?
InChIKeyNOCDRVBGQNLRFR-ISEYYBFVSA-N
XLogP11.63
TPSA418.53 Ų
H-Bond Donors14
H-Bond Acceptors29
Rotatable Bonds21
Heavy Atoms158
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002199.15
LogP ≤ 511.63
H-Bond Donors ≤ 514
H-Bond Acceptors ≤ 1029

Analyze (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide with MolForge

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Related Compounds

N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-chlorobenzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2,6-difluorobenzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-methylbenzamide;N-[6-amino-5-[1-methyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-4-tert-butylbenzamide;N-[6-amino-5-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-8-yl]-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[6-(trifluoromethyl)imidazo[2,1-b][1,3]thiazol-5-yl]-2-pyridinyl]-4-methylbenzamide
CID 157411317
N-[6-amino-5-(4-chloro-2,3-difluorophenyl)-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2-chlorobenzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-2,6-difluorobenzamide;N-[6-amino-5-[1-ethyl-3-(trifluoromethyl)pyrazol-5-yl]-2-pyridinyl]-3-methylbenzamide;N-[6-amino-5-[6-(trifluoromethyl)imidazo[1,2-a]pyridin-8-yl]-2-pyridinyl]-4-methylbenzamide;N-[6-amino-5-[6-(trifluoromethyl)imidazo[2,1-b][1,3]thiazol-5-yl]-2-pyridinyl]-4-methylbenzamide
CID 157707492
5-chloro-4-methylpyrimidin-2-amine;4-chloro-2-methyl-3-(trifluoromethyl)pyridine;2-(4,4-difluoropiperidin-1-yl)-4,5-dimethylpyrimidine;2,4-dimethyl-1H-indole;3,4-dimethylpyridazine;4,5-dimethylpyrimidin-2-amine;bis(4,5-dimethylpyrimidine);4,5-dimethylpyrimidine-2-carboxamide;4-(4,5-dimethylpyrimidin-2-yl)morpholine;4,6-dimethylquinazoline;4-(4,6-dimethylquinazolin-2-yl)morpholine;6-fluoro-2,4-dimethylquinazoline;6-fluoro-2,5-dimethylquinazoline;5-fluoro-4-methyl-7H-pyrrolo[2,3-d]pyrimidine;6-fluoro-5-methylquinoline;5-methylimidazo[1,2-c]pyrimidine;4-methyl-1H-indole;4-(1-methylisoquinolin-3-yl)morpholine;1-methylpyrrolo[1,2-c]pyrimidine;4-methyl-7H-pyrrolo[2,3-d]pyrimidine;4-methylquinazoline;4-(4-methylquinazolin-2-yl)morpholine;bis(4-methyl-5,6,7,8-tetrahydroquinazoline);4-methyl-1,3-thiazole;4-(4-methyl-1,3-thiazol-2-yl)morpholine;4-methyl-2-(trifluoromethyl)-1H-indole
CID 157957855
CID 158566393
CID 158566393
(1R,5S)-N-(2-imidazo[1,2-a]pyridin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-isoquinolin-1-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-isoquinolin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(3-methylnaphthalen-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methyl-2-pyridinyl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methyl-1,3-thiazol-2-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-quinolin-4-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-[3-(trifluoromethyl)-2-pyridinyl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 159386052
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(4-methylphthalazin-1-yl)butan-1-one;(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-methyl-1,7-naphthyridin-8-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161564085
(1S,5R)-N-[1-(7-chloro-1-methylindazol-3-yl)ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(1-cyclopropylimidazo[1,5-a]pyridin-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[1-(1,7-dimethylindazol-3-yl)ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;bis((1S,5R)-N-[1-(1-methylindazol-3-yl)ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide);(1S,5R)-N-[2-[6-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[7-(trifluoromethyl)imidazo[1,5-a]pyridin-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161833717
1-[(1R,5S)-3-azabicyclo[3.1.0]hexan-6-yl]-3-methyl-3-(4-methylphthalazin-1-yl)butan-1-one;(1S,5R)-N-[2-(6-chloropyrazolo[1,2-b]thiadiazol-4-ium-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide
CID 161863887
5-tert-butyl-1,3-dihydropyrrolo[2,3-b]pyridin-2-one;1-tert-butylindazole;5,8-dimethyl-6,7-dihydropteridine;dodecakis(2,2-dimethylpropane);ethane;imidazo[1,5-a]pyridine;methane;6-methyl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidine;1-methyl-3,4-dihydro-2H-quinoline;2-methylpropane;9-methylpurine;1-methylpyrazolo[4,5-b]pyridine;1-methylpyrazolo[4,5-c]pyridine;1-methylpyrazolo[5,4-c]pyridine;1-methylpyrrolo[2,3-b]pyridine;1-methylpyrrolo[2,3-c]pyridine;1-methylpyrrolo[3,2-c]pyridine;5-methylpyrrolo[3,2-d]pyrimidine;quinoline;thieno[2,3-d]pyrimidine
CID 158915107
4-amino-2-[6-chloro-3-[(2,3,6-trifluorophenyl)methyl]imidazo[1,5-a]pyridin-1-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;4-amino-2-[5-chloro-3-[(2,3,6-trifluorophenyl)methyl]thieno[2,3-c]pyrazol-1-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one;4-amino-5,5-dimethyl-2-[7-[(2,3,6-trifluorophenyl)methyl]imidazo[1,5-b]pyridazin-5-yl]-7H-pyrrolo[2,3-d]pyrimidin-6-one;4-amino-2-[6-fluoro-3-[(2,3,6-trifluorophenyl)methyl]imidazo[1,5-a]pyridin-1-yl]-5,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-6-one
CID 159891341
3-Cyclopropyl-1-[3-(difluoromethyl)-2-(1-methylimidazol-4-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;3-cyclopropyl-1-[3-(difluoromethyl)-2-(2-methyl-1,3-thiazol-5-yl)quinolin-5-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;3-cyclopropyl-5,7-dimethyl-1-[3-(4-methylimidazol-1-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;3-cyclopropyl-5,7-dimethyl-1-[3-(3-methyl-1,2,4-triazol-1-yl)isoquinolin-8-yl]-5,8-dihydroimidazo[1,5-a]pyrazin-6-one;3-cyclopropyl-1-[3-(3,4-dimethylpyrazol-1-yl)isoquinolin-8-yl]-5,7-dimethyl-5,8-dihydroimidazo[1,5-a]pyrazin-6-one
CID 160227950
CID 160717404
CID 160717404

Frequently Asked Questions

What is the IUPAC name of (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The IUPAC name of (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide (CID 159836120) is (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide.
What is the SMILES notation for (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The canonical SMILES for (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1c(Cl)nc2sccn12.CC(C)(NC(=O)C1[C@H]2CNC[C@@H]12)c1ncc2ccncn12.Cc1cc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccn12.Cc1ccc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)n2ccnc12.Cc1nnc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccccc12.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2ccc(F)cc21.Cn1nc(C(C)(C)NC(=O)C2[C@H]3CNC[C@@H]23)c2cccc(C(F)(F)F)c21.
What is the InChIKey of (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
The InChIKey is NOCDRVBGQNLRFR-ISEYYBFVSA-N. The full InChI is InChI=1S/C18H21F3N4O.C18H22N4O.C18H23N3O.C17H21FN4O.C17H22N4O.C15H19N5O.C14H17ClN4OS/c1-17(2,23-16(26)13-10-7-22-8-11(10)13)15-9-5-4-6-12(18(19,20)21)14(9)25(3)24-15;1-10-11-6-4-5-7-12(11)16(22-21-10)18(2,3)20-17(23)15-13-8-19-9-14(13)15;1-11-8-14(15-6-4-5-7-21(11)15)18(2,3)20-17(22)16-12-9-19-10-13(12)16;1-17(2,20-16(23)14-11-7-19-8-12(11)14)15-10-5-4-9(18)6-13(10)22(3)21-15;1-10-4-5-13(21-7-6-19-15(10)21)17(2,3)20-16(22)14-11-8-18-9-12(11)14;1-15(2,14-18-5-9-3-4-16-8-20(9)14)19-13(21)12-10-6-17-7-11(10)12;1-14(2,10-11(15)17-13-19(10)3-4-21-13)18-12(20)9-7-5-16-6-8(7)9/h4-6,10-11,13,22H,7-8H2,1-3H3,(H,23,26);4-7,13-15,19H,8-9H2,1-3H3,(H,20,23);4-8,12-13,16,19H,9-10H2,1-3H3,(H,20,22);4-6,11-12,14,19H,7-8H2,1-3H3,(H,20,23);4-7,11-12,14,18H,8-9H2,1-3H3,(H,20,22);3-5,8,10-12,17H,6-7H2,1-2H3,(H,19,21);3-4,7-9,16H,5-6H2,1-2H3,(H,18,20)/t10-,11+,13?;13-,14+,15?;12-,13+,16?;2*11-,12+,14?;10-,11+,12?;7-,8+,9?.
What are the key properties of (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide?
(1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide has a molecular weight of 2199.15 g/mol, XLogP of 11.63, 21 rotatable bonds, 14 hydrogen bond donors, and 29 hydrogen bond acceptors.
Where does this data come from?
All data for (1R,5S)-N-[2-(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-(6-fluoro-1-methylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-(2-imidazo[1,5-c]pyrimidin-3-ylpropan-2-yl)-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(8-methylimidazo[1,2-a]pyridin-5-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(3-methylindolizin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1R,5S)-N-[2-(4-methylphthalazin-1-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide;(1S,5R)-N-[2-[1-methyl-7-(trifluoromethyl)indazol-3-yl]propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide is sourced from PubChem (CID 159836120), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).