(4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

C115H138Cl5F3N26 — CID 159839803

About (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine

(4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (PubChem CID 159839803) has the molecular formula C115H138Cl5F3N26 and a molecular weight of 2118.81 g/mol. Its IUPAC name is (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.

Molecular Properties

• Compound Name: (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
• PubChem CID: 159839803
• Molecular Formula: C115H138Cl5F3N26
• Molecular Weight: 2118.81 g/mol
• Exact Mass: 2115.00
• IUPAC Name: (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine
• SMILES: CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(C(F)(F)F)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccc3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccn3)c3nccn13)CC2
• InChI: InChI=1S/C24H28F3N5.2C23H27Cl2N5.C23H28ClN5.C22H28N6/c1-16-20(17-5-3-6-18(15-17)24(25,26)27)21-29-11-14-32(21)22(30-16)31-12-9-23(10-13-31)8-4-7-19(23)28-2;2*1-15-19(16-5-3-6-17(24)20(16)25)21-27-11-14-30(21)22(28-15)29-12-9-23(10-13-29)8-4-7-18(23)26-2;1-16-20(17-6-3-4-7-18(17)24)21-26-12-15-29(21)22(27-16)28-13-10-23(11-14-28)9-5-8-19(23)25-2;1-16-19(17-6-3-4-11-24-17)20-25-12-15-28(20)21(26-16)27-13-9-22(10-14-27)8-5-7-18(22)23-2/h3,5-6,11,14-15,19,28H,4,7-10,12-13H2,1-2H3;2*3,5-6,11,14,18,26H,4,7-10,12-13H2,1-2H3;3-4,6-7,12,15,19,25H,5,8-11,13-14H2,1-2H3;3-4,6,11-12,15,18,23H,5,7-10,13-14H2,1-2H3/t19-;2*18-;19-;18-/m11111/s1
• InChIKey: NONNNFKJAVBCEG-VURLWQMHSA-N
• XLogP: 24.00
• TPSA: 240.19 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 26
• Rotatable Bonds: 15
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2118.81
LogP ≤ 5	24.00
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The IUPAC name of (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine (CID 159839803) is (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine.

What is the SMILES notation for (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The canonical SMILES for (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(C(F)(F)F)c3)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3cccc(Cl)c3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccc3Cl)c3nccn13)CC2.CN[C@@H]1CCCC12CCN(c1nc(C)c(-c3ccccn3)c3nccn13)CC2.

What is the InChIKey of (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

The InChIKey is NONNNFKJAVBCEG-VURLWQMHSA-N. The full InChI is InChI=1S/C24H28F3N5.2C23H27Cl2N5.C23H28ClN5.C22H28N6/c1-16-20(17-5-3-6-18(15-17)24(25,26)27)21-29-11-14-32(21)22(30-16)31-12-9-23(10-13-31)8-4-7-19(23)28-2;2*1-15-19(16-5-3-6-17(24)20(16)25)21-27-11-14-30(21)22(28-15)29-12-9-23(10-13-29)8-4-7-18(23)26-2;1-16-20(17-6-3-4-7-18(17)24)21-26-12-15-29(21)22(27-16)28-13-10-23(11-14-28)9-5-8-19(23)25-2;1-16-19(17-6-3-4-11-24-17)20-25-12-15-28(20)21(26-16)27-13-9-22(10-14-27)8-5-7-18(22)23-2/h3,5-6,11,14-15,19,28H,4,7-10,12-13H2,1-2H3;2*3,5-6,11,14,18,26H,4,7-10,12-13H2,1-2H3;3-4,6-7,12,15,19,25H,5,8-11,13-14H2,1-2H3;3-4,6,11-12,15,18,23H,5,7-10,13-14H2,1-2H3/t19-;2*18-;19-;18-/m11111/s1.

What are the key properties of (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine?

(4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine has a molecular weight of 2118.81 g/mol, XLogP of 24.00, 15 rotatable bonds, 5 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for (4R)-8-[8-(2-chlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine;bis((4R)-8-[8-(2,3-dichlorophenyl)-7-methylimidazo[1,2-c]pyrimidin-5-yl]-N-methyl-8-azaspiro[4.5]decan-4-amine);(4R)-N-methyl-8-(7-methyl-8-pyridin-2-ylimidazo[1,2-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-4-amine;(4R)-N-methyl-8-[7-methyl-8-[3-(trifluoromethyl)phenyl]imidazo[1,2-c]pyrimidin-5-yl]-8-azaspiro[4.5]decan-4-amine is sourced from PubChem (CID 159839803), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).