5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one

C115H74F2N24O15S5 — CID 159852181

About 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one

5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one (PubChem CID 159852181) has the molecular formula C115H74F2N24O15S5 and a molecular weight of 2230.34 g/mol. Its IUPAC name is 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one.

Molecular Properties

• Compound Name: 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one
• PubChem CID: 159852181
• Molecular Formula: C115H74F2N24O15S5
• Molecular Weight: 2230.34 g/mol
• Exact Mass: 2228.43
• IUPAC Name: 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one
• SMILES: C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)CCN5)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)OCCN5)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)OCCN5C(=O)C4CC4(F)F)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cncc(N5CCCCC5)c4)ccc32)S(=O)N1.O=C1COc2ncc(-c3ccc4c(cnn4C4=CC(=O)NS4=O)c3)cc2C1
• InChI: InChI=1S/C22H2.C21H15F2N5O4S.C20H19N5O2S.C18H12N4O4S.C17H13N5O3S.C17H13N5O2S/c1-3-5-7-9-11-13-15-17-19-21-22-20-18-16-14-12-10-8-6-4-2;22-21(23)8-14(21)20(30)27-3-4-32-16-6-12(9-24-19(16)27)11-1-2-15-13(5-11)10-25-28(15)18-7-17(29)26-33(18)31;26-19-10-20(28(27)23-19)25-18-5-4-14(8-16(18)12-22-25)15-9-17(13-21-11-15)24-6-2-1-3-7-24;23-14-5-11-4-12(7-19-18(11)26-9-14)10-1-2-15-13(3-10)8-20-22(15)17-6-16(24)21-27(17)25;23-15-7-16(26(24)21-15)22-13-2-1-10(5-12(13)9-20-22)11-6-14-17(19-8-11)18-3-4-25-14;23-15-7-16(25(24)21-15)22-14-2-1-10(5-13(14)9-20-22)12-6-11-3-4-18-17(11)19-8-12/h1-2H;1-2,5-7,9-10,14H,3-4,8H2,(H,26,29);4-5,8-13H,1-3,6-7H2,(H,23,26);1-4,6-8H,5,9H2,(H,21,24);1-2,5-9H,3-4H2,(H,18,19)(H,21,23);1-2,5-9H,3-4H2,(H,18,19)(H,21,23)
• InChIKey: NQBQLHXGJDWUHQ-UHFFFAOYSA-N
• XLogP: 9.38
• TPSA: 476.77 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 33
• Rotatable Bonds: 12
• Heavy Atoms: 161
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2230.34
LogP ≤ 5	9.38
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	33

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one?

The IUPAC name of 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one (CID 159852181) is 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one.

What is the SMILES notation for 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one?

The canonical SMILES for 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one is C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)CCN5)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)OCCN5)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cnc5c(c4)OCCN5C(=O)C4CC4(F)F)ccc32)S(=O)N1.O=C1C=C(n2ncc3cc(-c4cncc(N5CCCCC5)c4)ccc32)S(=O)N1.O=C1COc2ncc(-c3ccc4c(cnn4C4=CC(=O)NS4=O)c3)cc2C1.

What is the InChIKey of 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one?

The InChIKey is NQBQLHXGJDWUHQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H2.C21H15F2N5O4S.C20H19N5O2S.C18H12N4O4S.C17H13N5O3S.C17H13N5O2S/c1-3-5-7-9-11-13-15-17-19-21-22-20-18-16-14-12-10-8-6-4-2;22-21(23)8-14(21)20(30)27-3-4-32-16-6-12(9-24-19(16)27)11-1-2-15-13(5-11)10-25-28(15)18-7-17(29)26-33(18)31;26-19-10-20(28(27)23-19)25-18-5-4-14(8-16(18)12-22-25)15-9-17(13-21-11-15)24-6-2-1-3-7-24;23-14-5-11-4-12(7-19-18(11)26-9-14)10-1-2-15-13(3-10)8-20-22(15)17-6-16(24)21-27(17)25;23-15-7-16(26(24)21-15)22-13-2-1-10(5-12(13)9-20-22)11-6-14-17(19-8-11)18-3-4-25-14;23-15-7-16(25(24)21-15)22-14-2-1-10(5-13(14)9-20-22)12-6-11-3-4-18-17(11)19-8-12/h1-2H;1-2,5-7,9-10,14H,3-4,8H2,(H,26,29);4-5,8-13H,1-3,6-7H2,(H,23,26);1-4,6-8H,5,9H2,(H,21,24);1-2,5-9H,3-4H2,(H,18,19)(H,21,23);1-2,5-9H,3-4H2,(H,18,19)(H,21,23).

What are the key properties of 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one?

5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one has a molecular weight of 2230.34 g/mol, XLogP of 9.38, 12 rotatable bonds, 7 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[5-[4-(2,2-difluorocyclopropanecarbonyl)-2,3-dihydropyrido[3,2-b][1,4]oxazin-7-yl]indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-7-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;5-[5-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)indazol-1-yl]-1-oxo-1,2-thiazol-3-one;6-[1-(1,3-dioxo-1,2-thiazol-5-yl)indazol-5-yl]-4H-pyrano[2,3-b]pyridin-3-one;docosa-1,3,5,7,9,11,13,15,17,19,21-undecayne;1-oxo-5-[5-(5-piperidin-1-yl-3-pyridinyl)indazol-1-yl]-1,2-thiazol-3-one is sourced from PubChem (CID 159852181), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).