N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide

C110H91Cl2F17N20O17S10 — CID 159853175

About N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide

N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide (PubChem CID 159853175) has the molecular formula C110H91Cl2F17N20O17S10 and a molecular weight of 2679.60 g/mol. Its IUPAC name is N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide.

Molecular Properties

• Compound Name: N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide
• PubChem CID: 159853175
• Molecular Formula: C110H91Cl2F17N20O17S10
• Molecular Weight: 2679.60 g/mol
• Exact Mass: 2676.32
• IUPAC Name: N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide
• SMILES: CC(C)c1sc2c(c1CC(=O)Nc1nc(-c3ccc(C(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3cc(F)c(OC(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3cc(F)c(OCC(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3ccc(C(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.Cc1sc2c(c1CC(=O)Nc1nc(-c3ccc(Cl)c(Cl)c3)cs1)c(=O)n(C)c(=O)n2C
• InChI: InChI=1S/C23H19F5N4O4S2.C23H20F4N4O3S2.C22H18F4N4O4S2.C22H18F4N4O3S2.C20H16Cl2N4O3S2/c1-4-15-11(17-19(34)31(2)22(35)32(3)20(17)38-15)7-16(33)30-21-29-14(8-37-21)10-5-12(24)18(13(25)6-10)36-9-23(26,27)28;1-10(2)18-12(17-19(33)30(3)22(34)31(4)20(17)36-18)8-16(32)29-21-28-15(9-35-21)11-5-6-13(14(24)7-11)23(25,26)27;1-4-14-10(16-18(32)29(2)22(33)30(3)19(16)36-14)7-15(31)28-21-27-13(8-35-21)9-5-11(23)17(12(24)6-9)34-20(25)26;1-4-15-11(17-18(32)29(2)21(33)30(3)19(17)35-15)8-16(31)28-20-27-14(9-34-20)10-5-6-12(13(23)7-10)22(24,25)26;1-9-11(16-17(28)25(2)20(29)26(3)18(16)31-9)7-15(27)24-19-23-14(8-30-19)10-4-5-12(21)13(22)6-10/h5-6,8H,4,7,9H2,1-3H3,(H,29,30,33);5-7,9-10H,8H2,1-4H3,(H,28,29,32);5-6,8,20H,4,7H2,1-3H3,(H,27,28,31);5-7,9H,4,8H2,1-3H3,(H,27,28,31);4-6,8H,7H2,1-3H3,(H,23,24,27)
• InChIKey: NQEVMTDODJRBED-UHFFFAOYSA-N
• XLogP: 21.86
• TPSA: 448.41 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 42
• Rotatable Bonds: 28
• Heavy Atoms: 176
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2679.60
LogP ≤ 5	21.86
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	42

Frequently Asked Questions

What is the IUPAC name of N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide?

The IUPAC name of N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide (CID 159853175) is N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide.

What is the SMILES notation for N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide?

The canonical SMILES for N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide is CC(C)c1sc2c(c1CC(=O)Nc1nc(-c3ccc(C(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3cc(F)c(OC(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3cc(F)c(OCC(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.CCc1sc2c(c1CC(=O)Nc1nc(-c3ccc(C(F)(F)F)c(F)c3)cs1)c(=O)n(C)c(=O)n2C.Cc1sc2c(c1CC(=O)Nc1nc(-c3ccc(Cl)c(Cl)c3)cs1)c(=O)n(C)c(=O)n2C.

What is the InChIKey of N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide?

The InChIKey is NQEVMTDODJRBED-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H19F5N4O4S2.C23H20F4N4O3S2.C22H18F4N4O4S2.C22H18F4N4O3S2.C20H16Cl2N4O3S2/c1-4-15-11(17-19(34)31(2)22(35)32(3)20(17)38-15)7-16(33)30-21-29-14(8-37-21)10-5-12(24)18(13(25)6-10)36-9-23(26,27)28;1-10(2)18-12(17-19(33)30(3)22(34)31(4)20(17)36-18)8-16(32)29-21-28-15(9-35-21)11-5-6-13(14(24)7-11)23(25,26)27;1-4-14-10(16-18(32)29(2)22(33)30(3)19(16)36-14)7-15(31)28-21-27-13(8-35-21)9-5-11(23)17(12(24)6-9)34-20(25)26;1-4-15-11(17-18(32)29(2)21(33)30(3)19(17)35-15)8-16(31)28-20-27-14(9-34-20)10-5-6-12(13(23)7-10)22(24,25)26;1-9-11(16-17(28)25(2)20(29)26(3)18(16)31-9)7-15(27)24-19-23-14(8-30-19)10-4-5-12(21)13(22)6-10/h5-6,8H,4,7,9H2,1-3H3,(H,29,30,33);5-7,9-10H,8H2,1-4H3,(H,28,29,32);5-6,8,20H,4,7H2,1-3H3,(H,27,28,31);5-7,9H,4,8H2,1-3H3,(H,27,28,31);4-6,8H,7H2,1-3H3,(H,23,24,27).

What are the key properties of N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide?

N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide has a molecular weight of 2679.60 g/mol, XLogP of 21.86, 28 rotatable bonds, 5 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-2-(1,3,6-trimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[4-(difluoromethoxy)-3,5-difluorophenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;N-[4-[3,5-difluoro-4-(2,2,2-trifluoroethoxy)phenyl]-1,3-thiazol-2-yl]-2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)acetamide;2-(1,3-dimethyl-2,4-dioxo-6-propan-2-ylthieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide;2-(6-ethyl-1,3-dimethyl-2,4-dioxothieno[2,3-d]pyrimidin-5-yl)-N-[4-[3-fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]acetamide is sourced from PubChem (CID 159853175), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).