2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone

C275H276N56O11S11 — CID 159853280

IUPAC2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
SMILESCC1CN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)C1.CN(C)c1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CN1CCN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)CC1.CN1CCc2cc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)cc2C1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C(C)C)CC5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccc5c(c4)CCCC5)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1nnc(-c2ccc3cnc(CC(=O)c4ccc(N5CCN(C)CC5)nc4)cc3c2)s1
InChIInChI=1S/C27H30N6OS.2C26H28N6OS.2C25H26N6OS.2C25H25N5OS.C25H22N2OS.C24H24N6OS.C24H22N4OS.C23H20N4OS/c1-18(2)32-8-10-33(11-9-32)26-14-19(6-7-29-26)24(34)15-23-13-22-12-20(4-5-21(22)16-30-23)25-17-31-27(28-3)35-25;1-30(2)22-15-32(16-22)25-11-17(7-8-27-25)23(33)12-21-10-20-9-18(5-6-19(20)13-28-21)24-14-29-26(34-24)31(3)4;1-30(2)26-29-17-24(34-26)19-4-5-20-16-28-22(13-21(20)12-19)15-23(33)18-6-7-27-25(14-18)32-10-8-31(3)9-11-32;1-26-25-29-13-23(33-25)17-4-5-18-12-28-20(9-19(18)8-17)11-22(32)16-6-7-27-24(10-16)31-14-21(15-31)30(2)3;1-26-25-29-16-23(33-25)18-3-4-19-15-28-21(12-20(19)11-18)14-22(32)17-5-6-27-24(13-17)31-9-7-30(2)8-10-31;1-16-14-30(15-16)24-10-17(6-7-26-24)22(31)11-21-9-20-8-18(4-5-19(20)12-27-21)23-13-28-25(32-23)29(2)3;1-17-27-16-24(32-17)19-3-4-20-15-28-22(12-21(20)11-19)14-23(31)18-5-6-26-25(13-18)30-9-7-29(2)8-10-30;1-16-26-15-25(29-16)20-8-9-21-14-27-23(12-22(21)11-20)13-24(28)19-7-6-17-4-2-3-5-18(17)10-19;1-16-27-28-24(32-16)17-3-4-18-14-25-21(12-20(18)11-17)13-22(31)19-5-6-23(26-15-19)30-9-7-29(2)8-10-30;1-28-7-6-15-8-16(2-5-19(15)14-28)22(29)11-21-10-20-9-17(3-4-18(20)12-26-21)23-13-27-24(25)30-23;1-27-12-17-5-2-14(6-19(17)13-27)21(28)9-20-8-18-7-15(3-4-16(18)10-25-20)22-11-26-23(24)29-22/h4-7,12-14,16-18H,8-11,15H2,1-3H3,(H,28,31);5-11,13-14,22H,12,15-16H2,1-4H3;4-7,12-14,16-17H,8-11,15H2,1-3H3;4-10,12-13,21H,11,14-15H2,1-3H3,(H,26,29);3-6,11-13,15-16H,7-10,14H2,1-2H3,(H,26,29);4-10,12-13,16H,11,14-15H2,1-3H3;3-6,11-13,15-16H,7-10,14H2,1-2H3;6-12,14-15H,2-5,13H2,1H3;3-6,11-12,14-15H,7-10,13H2,1-2H3;2-5,8-10,12-13H,6-7,11,14H2,1H3,(H2,25,27);2-8,10-11H,9,12-13H2,1H3,(H2,24,26)
InChIKeyNQFCINGDMWEOFN-UHFFFAOYSA-N
MW4894.35 g/mol
LogP47.89
Rot. Bonds61

About 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone

2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone (PubChem CID 159853280) has the molecular formula C275H276N56O11S11 and a molecular weight of 4894.35 g/mol. Its IUPAC name is 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone.

Molecular Properties

Compound Name2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
PubChem CID159853280
Molecular FormulaC275H276N56O11S11
Molecular Weight4894.35 g/mol
Exact Mass4889.97
IUPAC Name2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone
SMILESCC1CN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)C1.CN(C)c1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CN1CCN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)CC1.CN1CCc2cc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)cc2C1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C(C)C)CC5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccc5c(c4)CCCC5)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1nnc(-c2ccc3cnc(CC(=O)c4ccc(N5CCN(C)CC5)nc4)cc3c2)s1
InChIInChI=1S/C27H30N6OS.2C26H28N6OS.2C25H26N6OS.2C25H25N5OS.C25H22N2OS.C24H24N6OS.C24H22N4OS.C23H20N4OS/c1-18(2)32-8-10-33(11-9-32)26-14-19(6-7-29-26)24(34)15-23-13-22-12-20(4-5-21(22)16-30-23)25-17-31-27(28-3)35-25;1-30(2)22-15-32(16-22)25-11-17(7-8-27-25)23(33)12-21-10-20-9-18(5-6-19(20)13-28-21)24-14-29-26(34-24)31(3)4;1-30(2)26-29-17-24(34-26)19-4-5-20-16-28-22(13-21(20)12-19)15-23(33)18-6-7-27-25(14-18)32-10-8-31(3)9-11-32;1-26-25-29-13-23(33-25)17-4-5-18-12-28-20(9-19(18)8-17)11-22(32)16-6-7-27-24(10-16)31-14-21(15-31)30(2)3;1-26-25-29-16-23(33-25)18-3-4-19-15-28-21(12-20(19)11-18)14-22(32)17-5-6-27-24(13-17)31-9-7-30(2)8-10-31;1-16-14-30(15-16)24-10-17(6-7-26-24)22(31)11-21-9-20-8-18(4-5-19(20)12-27-21)23-13-28-25(32-23)29(2)3;1-17-27-16-24(32-17)19-3-4-20-15-28-22(12-21(20)11-19)14-23(31)18-5-6-26-25(13-18)30-9-7-29(2)8-10-30;1-16-26-15-25(29-16)20-8-9-21-14-27-23(12-22(21)11-20)13-24(28)19-7-6-17-4-2-3-5-18(17)10-19;1-16-27-28-24(32-16)17-3-4-18-14-25-21(12-20(18)11-17)13-22(31)19-5-6-23(26-15-19)30-9-7-29(2)8-10-30;1-28-7-6-15-8-16(2-5-19(15)14-28)22(29)11-21-10-20-9-17(3-4-18(20)12-26-21)23-13-27-24(25)30-23;1-27-12-17-5-2-14(6-19(17)13-27)21(28)9-20-8-18-7-15(3-4-16(18)10-25-20)22-11-26-23(24)29-22/h4-7,12-14,16-18H,8-11,15H2,1-3H3,(H,28,31);5-11,13-14,22H,12,15-16H2,1-4H3;4-7,12-14,16-17H,8-11,15H2,1-3H3;4-10,12-13,21H,11,14-15H2,1-3H3,(H,26,29);3-6,11-13,15-16H,7-10,14H2,1-2H3,(H,26,29);4-10,12-13,16H,11,14-15H2,1-3H3;3-6,11-13,15-16H,7-10,14H2,1-2H3;6-12,14-15H,2-5,13H2,1H3;3-6,11-12,14-15H,7-10,13H2,1-2H3;2-5,8-10,12-13H,6-7,11,14H2,1H3,(H2,25,27);2-8,10-11H,9,12-13H2,1H3,(H2,24,26)
InChIKeyNQFCINGDMWEOFN-UHFFFAOYSA-N
XLogP47.89
TPSA740.29 Ų
H-Bond Donors5
H-Bond Acceptors78
Rotatable Bonds61
Heavy Atoms353
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004894.35
LogP ≤ 547.89
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1078

Analyze 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone?
The IUPAC name of 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone (CID 159853280) is 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone.
What is the SMILES notation for 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone?
The canonical SMILES for 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone is CC1CN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)C1.CN(C)c1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CN1CCN(c2cc(C(=O)Cc3cc4cc(-c5cnc(N(C)C)s5)ccc4cn3)ccn2)CC1.CN1CCc2cc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)ccc2C1.CN1Cc2ccc(C(=O)Cc3cc4cc(-c5cnc(N)s5)ccc4cn3)cc2C1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CC(N(C)C)C5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C(C)C)CC5)c4)cc3c2)s1.CNc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccc5c(c4)CCCC5)cc3c2)s1.Cc1ncc(-c2ccc3cnc(CC(=O)c4ccnc(N5CCN(C)CC5)c4)cc3c2)s1.Cc1nnc(-c2ccc3cnc(CC(=O)c4ccc(N5CCN(C)CC5)nc4)cc3c2)s1.
What is the InChIKey of 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone?
The InChIKey is NQFCINGDMWEOFN-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H30N6OS.2C26H28N6OS.2C25H26N6OS.2C25H25N5OS.C25H22N2OS.C24H24N6OS.C24H22N4OS.C23H20N4OS/c1-18(2)32-8-10-33(11-9-32)26-14-19(6-7-29-26)24(34)15-23-13-22-12-20(4-5-21(22)16-30-23)25-17-31-27(28-3)35-25;1-30(2)22-15-32(16-22)25-11-17(7-8-27-25)23(33)12-21-10-20-9-18(5-6-19(20)13-28-21)24-14-29-26(34-24)31(3)4;1-30(2)26-29-17-24(34-26)19-4-5-20-16-28-22(13-21(20)12-19)15-23(33)18-6-7-27-25(14-18)32-10-8-31(3)9-11-32;1-26-25-29-13-23(33-25)17-4-5-18-12-28-20(9-19(18)8-17)11-22(32)16-6-7-27-24(10-16)31-14-21(15-31)30(2)3;1-26-25-29-16-23(33-25)18-3-4-19-15-28-21(12-20(19)11-18)14-22(32)17-5-6-27-24(13-17)31-9-7-30(2)8-10-31;1-16-14-30(15-16)24-10-17(6-7-26-24)22(31)11-21-9-20-8-18(4-5-19(20)12-27-21)23-13-28-25(32-23)29(2)3;1-17-27-16-24(32-17)19-3-4-20-15-28-22(12-21(20)11-19)14-23(31)18-5-6-26-25(13-18)30-9-7-29(2)8-10-30;1-16-26-15-25(29-16)20-8-9-21-14-27-23(12-22(21)11-20)13-24(28)19-7-6-17-4-2-3-5-18(17)10-19;1-16-27-28-24(32-16)17-3-4-18-14-25-21(12-20(18)11-17)13-22(31)19-5-6-23(26-15-19)30-9-7-29(2)8-10-30;1-28-7-6-15-8-16(2-5-19(15)14-28)22(29)11-21-10-20-9-17(3-4-18(20)12-26-21)23-13-27-24(25)30-23;1-27-12-17-5-2-14(6-19(17)13-27)21(28)9-20-8-18-7-15(3-4-16(18)10-25-20)22-11-26-23(24)29-22/h4-7,12-14,16-18H,8-11,15H2,1-3H3,(H,28,31);5-11,13-14,22H,12,15-16H2,1-4H3;4-7,12-14,16-17H,8-11,15H2,1-3H3;4-10,12-13,21H,11,14-15H2,1-3H3,(H,26,29);3-6,11-13,15-16H,7-10,14H2,1-2H3,(H,26,29);4-10,12-13,16H,11,14-15H2,1-3H3;3-6,11-13,15-16H,7-10,14H2,1-2H3;6-12,14-15H,2-5,13H2,1H3;3-6,11-12,14-15H,7-10,13H2,1-2H3;2-5,8-10,12-13H,6-7,11,14H2,1H3,(H2,25,27);2-8,10-11H,9,12-13H2,1H3,(H2,24,26).
What are the key properties of 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone?
2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone has a molecular weight of 4894.35 g/mol, XLogP of 47.89, 61 rotatable bonds, 5 hydrogen bond donors, and 78 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-1,3-dihydroisoindol-5-yl)ethanone;2-[6-(2-amino-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(2-methyl-3,4-dihydro-1H-isoquinolin-6-yl)ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;1-[2-[3-(dimethylamino)azetidin-1-yl]-4-pyridinyl]-2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(3-methylazetidin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(dimethylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]ethanone;2-[6-[2-(methylamino)-1,3-thiazol-5-yl]isoquinolin-3-yl]-1-[2-(4-propan-2-ylpiperazin-1-yl)-4-pyridinyl]ethanone;1-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-2-[6-(5-methyl-1,3,4-thiadiazol-2-yl)isoquinolin-3-yl]ethanone;1-[2-(4-methylpiperazin-1-yl)-4-pyridinyl]-2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]ethanone;2-[6-(2-methyl-1,3-thiazol-5-yl)isoquinolin-3-yl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone is sourced from PubChem (CID 159853280), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).