N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine

C97H89ClF11N15S5 — CID 159868267

About N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine

N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine (PubChem CID 159868267) has the molecular formula C97H89ClF11N15S5 and a molecular weight of 1869.65 g/mol. Its IUPAC name is N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine.

Molecular Properties

• Compound Name: N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine
• PubChem CID: 159868267
• Molecular Formula: C97H89ClF11N15S5
• Molecular Weight: 1869.65 g/mol
• Exact Mass: 1867.55
• IUPAC Name: N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine
• SMILES: Cc1cccc(C)c1Nc1c(-c2c(F)cccc2F)nc2sc(C)c(C)n12.Cc1cccc(Cl)c1Nc1c(-c2c(F)cccc2F)nc2sc(C)c(C)n12.Cc1sc2nc(-c3c(F)cccc3F)c(NC3CCCC3)n2c1C.Cc1sc2nc(-c3c(F)cccc3F)c(NC3CCCCC3)n2c1C.Cc1sc2nc(-c3c(F)cccc3F)c(Nc3ccc(F)cc3)n2c1C
• InChI: InChI=1S/C21H19F2N3S.C20H16ClF2N3S.C19H14F3N3S.C19H21F2N3S.C18H19F2N3S/c1-11-7-5-8-12(2)18(11)24-20-19(17-15(22)9-6-10-16(17)23)25-21-26(20)13(3)14(4)27-21;1-10-6-4-7-13(21)17(10)24-19-18(16-14(22)8-5-9-15(16)23)25-20-26(19)11(2)12(3)27-20;1-10-11(2)26-19-24-17(16-14(21)4-3-5-15(16)22)18(25(10)19)23-13-8-6-12(20)7-9-13;1-11-12(2)25-19-23-17(16-14(20)9-6-10-15(16)21)18(24(11)19)22-13-7-4-3-5-8-13;1-10-11(2)24-18-22-16(15-13(19)8-5-9-14(15)20)17(23(10)18)21-12-6-3-4-7-12/h5-10,24H,1-4H3;4-9,24H,1-3H3;3-9,23H,1-2H3;6,9-10,13,22H,3-5,7-8H2,1-2H3;5,8-9,12,21H,3-4,6-7H2,1-2H3
• InChIKey: NRZVYDPSPDXWKX-UHFFFAOYSA-N
• XLogP: 29.84
• TPSA: 146.65 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 20
• Rotatable Bonds: 15
• Heavy Atoms: 129
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1869.65
LogP ≤ 5	29.84
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	20

Frequently Asked Questions

What is the IUPAC name of N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine?

The IUPAC name of N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine (CID 159868267) is N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine.

What is the SMILES notation for N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine?

The canonical SMILES for N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine is Cc1cccc(C)c1Nc1c(-c2c(F)cccc2F)nc2sc(C)c(C)n12.Cc1cccc(Cl)c1Nc1c(-c2c(F)cccc2F)nc2sc(C)c(C)n12.Cc1sc2nc(-c3c(F)cccc3F)c(NC3CCCC3)n2c1C.Cc1sc2nc(-c3c(F)cccc3F)c(NC3CCCCC3)n2c1C.Cc1sc2nc(-c3c(F)cccc3F)c(Nc3ccc(F)cc3)n2c1C.

What is the InChIKey of N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine?

The InChIKey is NRZVYDPSPDXWKX-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H19F2N3S.C20H16ClF2N3S.C19H14F3N3S.C19H21F2N3S.C18H19F2N3S/c1-11-7-5-8-12(2)18(11)24-20-19(17-15(22)9-6-10-16(17)23)25-21-26(20)13(3)14(4)27-21;1-10-6-4-7-13(21)17(10)24-19-18(16-14(22)8-5-9-15(16)23)25-20-26(19)11(2)12(3)27-20;1-10-11(2)26-19-24-17(16-14(21)4-3-5-15(16)22)18(25(10)19)23-13-8-6-12(20)7-9-13;1-11-12(2)25-19-23-17(16-14(20)9-6-10-15(16)21)18(24(11)19)22-13-7-4-3-5-8-13;1-10-11(2)24-18-22-16(15-13(19)8-5-9-14(15)20)17(23(10)18)21-12-6-3-4-7-12/h5-10,24H,1-4H3;4-9,24H,1-3H3;3-9,23H,1-2H3;6,9-10,13,22H,3-5,7-8H2,1-2H3;5,8-9,12,21H,3-4,6-7H2,1-2H3.

What are the key properties of N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine?

N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine has a molecular weight of 1869.65 g/mol, XLogP of 29.84, 15 rotatable bonds, 5 hydrogen bond donors, and 20 hydrogen bond acceptors.

Where does this data come from?

All data for N-(2-chloro-6-methylphenyl)-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclohexyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;N-cyclopentyl-6-(2,6-difluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(2,6-dimethylphenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine;6-(2,6-difluorophenyl)-N-(4-fluorophenyl)-2,3-dimethylimidazo[2,1-b][1,3]thiazol-5-amine is sourced from PubChem (CID 159868267), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).