1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile

C145H149F17N34O4S5 — CID 159883514

About 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile

1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile (PubChem CID 159883514) has the molecular formula C145H149F17N34O4S5 and a molecular weight of 2915.32 g/mol. Its IUPAC name is 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile.

Molecular Properties

• Compound Name: 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile
• PubChem CID: 159883514
• Molecular Formula: C145H149F17N34O4S5
• Molecular Weight: 2915.32 g/mol
• Exact Mass: 2913.08
• IUPAC Name: 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile
• SMILES: CC(=O)Cn1c(C#N)cc2c(C(F)F)c(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc21.CCCCC(O)(CO)Cn1c(C#N)cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc21.Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C#N)n2CC1=CCN=N1.Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C)n2CC1=CCN=N1.N#Cc1cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc2n1CC1=CC(OCC2CC2)=NC1
• InChI: InChI=1S/C32H32F3N7OS.C30H35F3N6O2S.C28H27F3N8S.C28H30F3N7S.C27H25F5N6OS/c33-32(34,35)13-26-12-27-30(38-19-39-31(27)44-26)40-24-5-7-41(8-6-24)16-21-3-4-28-23(9-21)11-25(14-36)42(28)17-22-10-29(37-15-22)43-18-20-1-2-20;1-2-3-8-29(41,18-40)17-39-23(15-34)12-21-11-20(4-5-26(21)39)16-38-9-6-22(7-10-38)37-27-25-13-24(14-30(31,32)33)42-28(25)36-19-35-27;1-17-18(2-3-25-23(17)10-21(13-32)39(25)15-20-4-7-35-37-20)14-38-8-5-19(6-9-38)36-26-24-11-22(12-28(29,30)31)40-27(24)34-16-33-26;1-17-11-23-18(2)19(3-4-25(23)38(17)15-21-5-8-34-36-21)14-37-9-6-20(7-10-37)35-26-24-12-22(13-28(29,30)31)39-27(24)33-16-32-26;1-15(39)12-38-18(11-33)8-20-22(38)3-2-16(23(20)24(28)29)13-37-6-4-17(5-7-37)36-25-21-9-19(10-27(30,31)32)40-26(21)35-14-34-25/h3-4,9-12,19-20,24H,1-2,5-8,13,15-18H2,(H,38,39,40);4-5,11-13,19,22,40-41H,2-3,6-10,14,16-18H2,1H3,(H,35,36,37);2-4,10-11,16,19H,5-9,12,14-15H2,1H3,(H,33,34,36);3-5,11-12,16,20H,6-10,13-15H2,1-2H3,(H,32,33,35);2-3,8-9,14,17,24H,4-7,10,12-13H2,1H3,(H,34,35,36)
• InChIKey: NTVLFCRHJOKMKX-UHFFFAOYSA-N
• XLogP: 31.45
• TPSA: 453.62 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 43
• Rotatable Bonds: 42
• Heavy Atoms: 205
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2915.32
LogP ≤ 5	31.45
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	43

Frequently Asked Questions

What is the IUPAC name of 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?

The IUPAC name of 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile (CID 159883514) is 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile.

What is the SMILES notation for 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?

The canonical SMILES for 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile is CC(=O)Cn1c(C#N)cc2c(C(F)F)c(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc21.CCCCC(O)(CO)Cn1c(C#N)cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc21.Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C#N)n2CC1=CCN=N1.Cc1c(CN2CCC(Nc3ncnc4sc(CC(F)(F)F)cc34)CC2)ccc2c1cc(C)n2CC1=CCN=N1.N#Cc1cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)ccc2n1CC1=CC(OCC2CC2)=NC1.

What is the InChIKey of 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?

The InChIKey is NTVLFCRHJOKMKX-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H32F3N7OS.C30H35F3N6O2S.C28H27F3N8S.C28H30F3N7S.C27H25F5N6OS/c33-32(34,35)13-26-12-27-30(38-19-39-31(27)44-26)40-24-5-7-41(8-6-24)16-21-3-4-28-23(9-21)11-25(14-36)42(28)17-22-10-29(37-15-22)43-18-20-1-2-20;1-2-3-8-29(41,18-40)17-39-23(15-34)12-21-11-20(4-5-26(21)39)16-38-9-6-22(7-10-38)37-27-25-13-24(14-30(31,32)33)42-28(25)36-19-35-27;1-17-18(2-3-25-23(17)10-21(13-32)39(25)15-20-4-7-35-37-20)14-38-8-5-19(6-9-38)36-26-24-11-22(12-28(29,30)31)40-27(24)34-16-33-26;1-17-11-23-18(2)19(3-4-25(23)38(17)15-21-5-8-34-36-21)14-37-9-6-20(7-10-37)35-26-24-12-22(13-28(29,30)31)39-27(24)33-16-32-26;1-15(39)12-38-18(11-33)8-20-22(38)3-2-16(23(20)24(28)29)13-37-6-4-17(5-7-37)36-25-21-9-19(10-27(30,31)32)40-26(21)35-14-34-25/h3-4,9-12,19-20,24H,1-2,5-8,13,15-18H2,(H,38,39,40);4-5,11-13,19,22,40-41H,2-3,6-10,14,16-18H2,1H3,(H,35,36,37);2-4,10-11,16,19H,5-9,12,14-15H2,1H3,(H,33,34,36);3-5,11-12,16,20H,6-10,13-15H2,1-2H3,(H,32,33,35);2-3,8-9,14,17,24H,4-7,10,12-13H2,1H3,(H,34,35,36).

What are the key properties of 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile?

1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile has a molecular weight of 2915.32 g/mol, XLogP of 31.45, 42 rotatable bonds, 7 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[[5-(cyclopropylmethoxy)-2H-pyrrol-3-yl]methyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-(difluoromethyl)-1-(2-oxopropyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;N-[1-[[2,4-dimethyl-1-(3H-pyrazol-5-ylmethyl)indol-5-yl]methyl]piperidin-4-yl]-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-amine;1-[2-hydroxy-2-(hydroxymethyl)hexyl]-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile;4-methyl-1-(3H-pyrazol-5-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]methyl]indole-2-carbonitrile is sourced from PubChem (CID 159883514), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).