2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol

C192H116N24O2S6 — CID 159884545

IUPAC2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol
SMILESOc1ccccc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccc4sc5cc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)ccc5c4c3)n2)c1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6ccc7sc8ccccc8c7c6)n5)cc34)n2)cc1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6cccc7c6sc6ccccc67)n5)cc34)n2)cc1.c1ccc(Oc2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5sc6cc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)ccc6c5c4)n3)c2)cc1
InChIInChI=1S/2C48H30N6OS.2C48H28N6S2/c1-5-14-31(15-6-1)43-49-44(32-16-7-2-8-17-32)53-48(52-43)36-24-26-39-40-29-35(25-27-41(40)56-42(39)30-36)47-51-45(33-18-9-3-10-19-33)50-46(54-47)34-20-13-23-38(28-34)55-37-21-11-4-12-22-37;55-40-22-11-10-21-37(40)33-19-12-20-34(27-33)46-50-45(32-17-8-3-9-18-32)51-47(54-46)35-24-26-41-39(28-35)38-25-23-36(29-42(38)56-41)48-52-43(30-13-4-1-5-14-30)49-44(53-48)31-15-6-2-7-16-31;1-4-13-29(14-5-1)43-49-44(30-15-6-2-7-16-30)51-47(50-43)33-23-25-35-38-27-32(24-26-40(38)55-41(35)28-33)46-52-45(31-17-8-3-9-18-31)53-48(54-46)37-21-12-20-36-34-19-10-11-22-39(34)56-42(36)37;1-4-12-29(13-5-1)43-49-44(30-14-6-2-7-15-30)53-48(52-43)34-20-23-36-38-27-33(22-25-41(38)56-42(36)28-34)47-51-45(31-16-8-3-9-17-31)50-46(54-47)32-21-24-40-37(26-32)35-18-10-11-19-39(35)55-40/h1-30H;1-29,55H;2*1-28H
InChIKeyNTYQHRLZQRTWHT-UHFFFAOYSA-N
MW2983.61 g/mol
LogP49.61
Rot. Bonds27

About 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol

2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol (PubChem CID 159884545) has the molecular formula C192H116N24O2S6 and a molecular weight of 2983.61 g/mol. Its IUPAC name is 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol.

Molecular Properties

Compound Name2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol
PubChem CID159884545
Molecular FormulaC192H116N24O2S6
Molecular Weight2983.61 g/mol
Exact Mass2980.80
IUPAC Name2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol
SMILESOc1ccccc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccc4sc5cc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)ccc5c4c3)n2)c1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6ccc7sc8ccccc8c7c6)n5)cc34)n2)cc1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6cccc7c6sc6ccccc67)n5)cc34)n2)cc1.c1ccc(Oc2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5sc6cc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)ccc6c5c4)n3)c2)cc1
InChIInChI=1S/2C48H30N6OS.2C48H28N6S2/c1-5-14-31(15-6-1)43-49-44(32-16-7-2-8-17-32)53-48(52-43)36-24-26-39-40-29-35(25-27-41(40)56-42(39)30-36)47-51-45(33-18-9-3-10-19-33)50-46(54-47)34-20-13-23-38(28-34)55-37-21-11-4-12-22-37;55-40-22-11-10-21-37(40)33-19-12-20-34(27-33)46-50-45(32-17-8-3-9-18-32)51-47(54-46)35-24-26-41-39(28-35)38-25-23-36(29-42(38)56-41)48-52-43(30-13-4-1-5-14-30)49-44(53-48)31-15-6-2-7-16-31;1-4-13-29(14-5-1)43-49-44(30-15-6-2-7-16-30)51-47(50-43)33-23-25-35-38-27-32(24-26-40(38)55-41(35)28-33)46-52-45(31-17-8-3-9-18-31)53-48(54-46)37-21-12-20-36-34-19-10-11-22-39(34)56-42(36)37;1-4-12-29(13-5-1)43-49-44(30-14-6-2-7-15-30)53-48(52-43)34-20-23-36-38-27-33(22-25-41(38)56-42(36)28-34)47-51-45(31-16-8-3-9-17-31)50-46(54-47)32-21-24-40-37(26-32)35-18-10-11-19-39(35)55-40/h1-30H;1-29,55H;2*1-28H
InChIKeyNTYQHRLZQRTWHT-UHFFFAOYSA-N
XLogP49.61
TPSA338.82 Ų
H-Bond Donors1
H-Bond Acceptors32
Rotatable Bonds27
Heavy Atoms224
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002983.61
LogP ≤ 549.61
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 1032

Analyze 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol with MolForge

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Related Compounds

2-dibenzothiophen-4-yl-4-[3-[3-(4,6-diphenyl-1,3,5-triazin-2-yl)phenoxy]phenyl]-6-phenyl-1,3,5-triazine
CID 155050305
2-[3-(8-dibenzothiophen-4-yldibenzothiophen-3-yl)phenyl]-4,6-diphenyl-1,3,5-triazine
CID 155377191
2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine
CID 155050262
2-dibenzothiophen-3-yl-4-dibenzothiophen-4-yl-6-(4-phenylphenyl)-1,3,5-triazine
CID 176831433
2-dibenzothiophen-3-yl-4-[4-(8-phenyldibenzothiophen-4-yl)phenyl]-6-(3-phenylphenyl)-1,3,5-triazine
CID 168850235
2-[3-(8-dibenzothiophen-2-yldibenzothiophen-4-yl)phenyl]-4,6-diphenyl-1,3,5-triazine
CID 122679618
2-(8-dibenzothiophen-4-yldibenzothiophen-2-yl)-4,6-diphenyl-1,3,5-triazine
CID 166952729
2-dibenzothiophen-3-yl-4-dibenzothiophen-4-yl-6-(2-phenylphenyl)-1,3,5-triazine
CID 146669978
2-(6-dibenzothiophen-4-yldibenzothiophen-2-yl)-4,6-diphenyl-1,3,5-triazine
CID 166952783
2-(3-dibenzothiophen-1-ylphenyl)-4-(3-dibenzothiophen-4-ylphenyl)-6-(2-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-2-ylphenyl)-4-(4-dibenzothiophen-1-ylphenyl)-6-(3-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-3-ylphenyl)-4-(4-dibenzothiophen-1-ylphenyl)-6-(4-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-4-ylphenyl)-4-(4-dibenzothiophen-1-ylphenyl)-6-phenyl-1,3,5-triazine
CID 161029861
2-(3-dibenzothiophen-1-ylphenyl)-4-(2-phenylphenyl)-6-(4-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-2-ylphenyl)-4-(2-phenylphenyl)-6-(4-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-3-ylphenyl)-4-(2-phenylphenyl)-6-(4-phenylphenyl)-1,3,5-triazine;2-(3-dibenzothiophen-4-ylphenyl)-4-(2-phenylphenyl)-6-(4-phenylphenyl)-1,3,5-triazine
CID 167660422
2-dibenzothiophen-4-yl-4-phenyl-6-[4-[8-(3-phenylphenyl)dibenzothiophen-4-yl]phenyl]-1,3,5-triazine
CID 155329887

Frequently Asked Questions

What is the IUPAC name of 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol?
The IUPAC name of 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol (CID 159884545) is 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol.
What is the SMILES notation for 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol?
The canonical SMILES for 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol is Oc1ccccc1-c1cccc(-c2nc(-c3ccccc3)nc(-c3ccc4sc5cc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)ccc5c4c3)n2)c1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6ccc7sc8ccccc8c7c6)n5)cc34)n2)cc1.c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3ccc(-c5nc(-c6ccccc6)nc(-c6cccc7c6sc6ccccc67)n5)cc34)n2)cc1.c1ccc(Oc2cccc(-c3nc(-c4ccccc4)nc(-c4ccc5sc6cc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)ccc6c5c4)n3)c2)cc1.
What is the InChIKey of 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol?
The InChIKey is NTYQHRLZQRTWHT-UHFFFAOYSA-N. The full InChI is InChI=1S/2C48H30N6OS.2C48H28N6S2/c1-5-14-31(15-6-1)43-49-44(32-16-7-2-8-17-32)53-48(52-43)36-24-26-39-40-29-35(25-27-41(40)56-42(39)30-36)47-51-45(33-18-9-3-10-19-33)50-46(54-47)34-20-13-23-38(28-34)55-37-21-11-4-12-22-37;55-40-22-11-10-21-37(40)33-19-12-20-34(27-33)46-50-45(32-17-8-3-9-18-32)51-47(54-46)35-24-26-41-39(28-35)38-25-23-36(29-42(38)56-41)48-52-43(30-13-4-1-5-14-30)49-44(53-48)31-15-6-2-7-16-31;1-4-13-29(14-5-1)43-49-44(30-15-6-2-7-16-30)51-47(50-43)33-23-25-35-38-27-32(24-26-40(38)55-41(35)28-33)46-52-45(31-17-8-3-9-18-31)53-48(54-46)37-21-12-20-36-34-19-10-11-22-39(34)56-42(36)37;1-4-12-29(13-5-1)43-49-44(30-14-6-2-7-15-30)53-48(52-43)34-20-23-36-38-27-33(22-25-41(38)56-42(36)28-34)47-51-45(31-16-8-3-9-17-31)50-46(54-47)32-21-24-40-37(26-32)35-18-10-11-19-39(35)55-40/h1-30H;1-29,55H;2*1-28H.
What are the key properties of 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol?
2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol has a molecular weight of 2983.61 g/mol, XLogP of 49.61, 27 rotatable bonds, 1 hydrogen bond donors, and 32 hydrogen bond acceptors.
Where does this data come from?
All data for 2-dibenzothiophen-2-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-dibenzothiophen-4-yl-4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazine;2-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-4-(3-phenoxyphenyl)-6-phenyl-1,3,5-triazine;2-[3-[4-[7-(4,6-diphenyl-1,3,5-triazin-2-yl)dibenzothiophen-2-yl]-6-phenyl-1,3,5-triazin-2-yl]phenyl]phenol is sourced from PubChem (CID 159884545), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).