2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide

C121H81Cl2F20N17O12 — CID 159887699

About 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide

2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide (PubChem CID 159887699) has the molecular formula C121H81Cl2F20N17O12 and a molecular weight of 2415.95 g/mol. Its IUPAC name is 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide.

Molecular Properties

• Compound Name: 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide
• PubChem CID: 159887699
• Molecular Formula: C121H81Cl2F20N17O12
• Molecular Weight: 2415.95 g/mol
• Exact Mass: 2413.53
• IUPAC Name: 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide
• SMILES: Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cncc3F)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1ccc(NC(=O)c3ccccc3Cl)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cccc3F)cn1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cncc3F)cn1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3Cl)cn1)CC(F)(F)O2
• InChI: InChI=1S/C21H15ClF2N2O2.C21H14F4N2O2.C20H14ClF2N3O2.2C20H13F4N3O2.C19H12F4N4O2/c1-12-8-18-14(10-21(23,24)28-18)9-16(12)13-6-7-19(25-11-13)26-20(27)15-4-2-3-5-17(15)22;1-11-7-17-13(9-21(24,25)29-17)8-14(11)12-5-6-18(26-10-12)27-20(28)19-15(22)3-2-4-16(19)23;1-11-6-17-12(8-20(22,23)28-17)7-14(11)16-9-25-18(10-24-16)26-19(27)13-4-2-3-5-15(13)21;1-10-4-16-12(6-20(23,24)29-16)5-13(10)11-2-3-17(26-7-11)27-19(28)18-14(21)8-25-9-15(18)22;1-10-5-16-11(7-20(23,24)29-16)6-12(10)15-8-26-17(9-25-15)27-19(28)18-13(21)3-2-4-14(18)22;1-9-2-15-10(4-19(22,23)29-15)3-11(9)14-7-26-16(8-25-14)27-18(28)17-12(20)5-24-6-13(17)21/h2-9,11H,10H2,1H3,(H,25,26,27);2-8,10H,9H2,1H3,(H,26,27,28);2-7,9-10H,8H2,1H3,(H,25,26,27);2-5,7-9H,6H2,1H3,(H,26,27,28);2-6,8-9H,7H2,1H3,(H,26,27,28);2-3,5-8H,4H2,1H3,(H,26,27,28)
• InChIKey: NUIPCKZRGPWUHH-UHFFFAOYSA-N
• XLogP: 28.42
• TPSA: 371.77 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 23
• Rotatable Bonds: 18
• Heavy Atoms: 172
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2415.95
LogP ≤ 5	28.42
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	23

Frequently Asked Questions

What is the IUPAC name of 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide?

The IUPAC name of 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide (CID 159887699) is 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide.

What is the SMILES notation for 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide?

The canonical SMILES for 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide is Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cccc3F)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1ccc(NC(=O)c3c(F)cncc3F)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1ccc(NC(=O)c3ccccc3Cl)nc1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cccc3F)cn1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3c(F)cncc3F)cn1)CC(F)(F)O2.Cc1cc2c(cc1-c1cnc(NC(=O)c3ccccc3Cl)cn1)CC(F)(F)O2.

What is the InChIKey of 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide?

The InChIKey is NUIPCKZRGPWUHH-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H15ClF2N2O2.C21H14F4N2O2.C20H14ClF2N3O2.2C20H13F4N3O2.C19H12F4N4O2/c1-12-8-18-14(10-21(23,24)28-18)9-16(12)13-6-7-19(25-11-13)26-20(27)15-4-2-3-5-17(15)22;1-11-7-17-13(9-21(24,25)29-17)8-14(11)12-5-6-18(26-10-12)27-20(28)19-15(22)3-2-4-16(19)23;1-11-6-17-12(8-20(22,23)28-17)7-14(11)16-9-25-18(10-24-16)26-19(27)13-4-2-3-5-15(13)21;1-10-4-16-12(6-20(23,24)29-16)5-13(10)11-2-3-17(26-7-11)27-19(28)18-14(21)8-25-9-15(18)22;1-10-5-16-11(7-20(23,24)29-16)6-12(10)15-8-26-17(9-25-15)27-19(28)18-13(21)3-2-4-14(18)22;1-9-2-15-10(4-19(22,23)29-15)3-11(9)14-7-26-16(8-25-14)27-18(28)17-12(20)5-24-6-13(17)21/h2-9,11H,10H2,1H3,(H,25,26,27);2-8,10H,9H2,1H3,(H,26,27,28);2-7,9-10H,8H2,1H3,(H,25,26,27);2-5,7-9H,6H2,1H3,(H,26,27,28);2-6,8-9H,7H2,1H3,(H,26,27,28);2-3,5-8H,4H2,1H3,(H,26,27,28).

What are the key properties of 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide?

2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide has a molecular weight of 2415.95 g/mol, XLogP of 28.42, 18 rotatable bonds, 6 hydrogen bond donors, and 23 hydrogen bond acceptors.

Where does this data come from?

All data for 2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]benzamide;2-chloro-N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]benzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)pyrazin-2-yl]-3,5-difluoropyridine-4-carboxamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-2,6-difluorobenzamide;N-[5-(2,2-difluoro-6-methyl-3H-1-benzofuran-5-yl)-2-pyridinyl]-3,5-difluoropyridine-4-carboxamide is sourced from PubChem (CID 159887699), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).