6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine

C184H235Cl2F5N40O3S — CID 159896777

About 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine

6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine (PubChem CID 159896777) has the molecular formula C184H235Cl2F5N40O3S and a molecular weight of 3253.14 g/mol. Its IUPAC name is 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine.

Molecular Properties

• Compound Name: 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine
• PubChem CID: 159896777
• Molecular Formula: C184H235Cl2F5N40O3S
• Molecular Weight: 3253.14 g/mol
• Exact Mass: 3249.85
• IUPAC Name: 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine
• SMILES: CC1(C)CN(CCCCN2CCCC2)Cc2cc(Nc3nccc4c3CCN(c3ncccc3F)C4)ccc21.CC1(C)CN(CCCCN2CCCC2)Cc2cc(Nc3ncnc4c3CCN(c3ncccc3F)C4)ccc21.CC1(C)CN(CCCN2CCCCC2)Cc2cc(Nc3ncnc4c3CCN(c3ncccc3S(C)(=O)=O)C4)ccc21.CC1(C)CN(CCN2CCOCC2)Cc2cc(Nc3nccc4c3CCN(c3ncccc3C(F)(F)F)C4)ccc21.CN(C)CCN1Cc2cc(Nc3nccc4c3CCN(c3ncccc3Cl)C4)ccc2C(C)(C)C1.CN1CCN(CCN2Cc3cc(Nc4ncnc5c4CCN(c4ncccc4Cl)C5)ccc3C(C)(C)C2)CC1
• InChI: InChI=1S/C32H41FN6.C32H43N7O2S.C31H37F3N6O.C31H40FN7.C30H39ClN8.C28H35ClN6/c1-32(2)23-38(18-6-5-17-37-15-3-4-16-37)21-25-20-26(9-10-28(25)32)36-30-27-12-19-39(22-24(27)11-14-34-30)31-29(33)8-7-13-35-31;1-32(2)22-38(17-8-16-37-14-5-4-6-15-37)20-24-19-25(10-11-27(24)32)36-30-26-12-18-39(21-28(26)34-23-35-30)31-29(42(3,40)41)9-7-13-33-31;1-30(2)21-39(13-12-38-14-16-41-17-15-38)19-23-18-24(5-6-26(23)30)37-28-25-8-11-40(20-22(25)7-10-35-28)29-27(31(32,33)34)4-3-9-36-29;1-31(2)21-38(16-6-5-15-37-13-3-4-14-37)19-23-18-24(9-10-26(23)31)36-29-25-11-17-39(20-28(25)34-22-35-29)30-27(32)8-7-12-33-30;1-30(2)20-38(16-15-37-13-11-36(3)12-14-37)18-22-17-23(6-7-25(22)30)35-28-24-8-10-39(19-27(24)33-21-34-28)29-26(31)5-4-9-32-29;1-28(2)19-34(15-14-33(3)4)17-21-16-22(7-8-24(21)28)32-26-23-10-13-35(18-20(23)9-12-30-26)27-25(29)6-5-11-31-27/h7-11,13-14,20H,3-6,12,15-19,21-23H2,1-2H3,(H,34,36);7,9-11,13,19,23H,4-6,8,12,14-18,20-22H2,1-3H3,(H,34,35,36);3-7,9-10,18H,8,11-17,19-21H2,1-2H3,(H,35,37);7-10,12,18,22H,3-6,11,13-17,19-21H2,1-2H3,(H,34,35,36);4-7,9,17,21H,8,10-16,18-20H2,1-3H3,(H,33,34,35);5-9,11-12,16H,10,13-15,17-19H2,1-4H3,(H,30,32)
• InChIKey: NVLDNXVGJGUESB-UHFFFAOYSA-N
• XLogP: 30.22
• TPSA: 370.46 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 43
• Rotatable Bonds: 42
• Heavy Atoms: 235
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3253.14
LogP ≤ 5	30.22
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	43

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine?

The IUPAC name of 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine (CID 159896777) is 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine.

What is the SMILES notation for 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine?

The canonical SMILES for 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine is CC1(C)CN(CCCCN2CCCC2)Cc2cc(Nc3nccc4c3CCN(c3ncccc3F)C4)ccc21.CC1(C)CN(CCCCN2CCCC2)Cc2cc(Nc3ncnc4c3CCN(c3ncccc3F)C4)ccc21.CC1(C)CN(CCCN2CCCCC2)Cc2cc(Nc3ncnc4c3CCN(c3ncccc3S(C)(=O)=O)C4)ccc21.CC1(C)CN(CCN2CCOCC2)Cc2cc(Nc3nccc4c3CCN(c3ncccc3C(F)(F)F)C4)ccc21.CN(C)CCN1Cc2cc(Nc3nccc4c3CCN(c3ncccc3Cl)C4)ccc2C(C)(C)C1.CN1CCN(CCN2Cc3cc(Nc4ncnc5c4CCN(c4ncccc4Cl)C5)ccc3C(C)(C)C2)CC1.

What is the InChIKey of 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine?

The InChIKey is NVLDNXVGJGUESB-UHFFFAOYSA-N. The full InChI is InChI=1S/C32H41FN6.C32H43N7O2S.C31H37F3N6O.C31H40FN7.C30H39ClN8.C28H35ClN6/c1-32(2)23-38(18-6-5-17-37-15-3-4-16-37)21-25-20-26(9-10-28(25)32)36-30-27-12-19-39(22-24(27)11-14-34-30)31-29(33)8-7-13-35-31;1-32(2)22-38(17-8-16-37-14-5-4-6-15-37)20-24-19-25(10-11-27(24)32)36-30-26-12-18-39(21-28(26)34-23-35-30)31-29(42(3,40)41)9-7-13-33-31;1-30(2)21-39(13-12-38-14-16-41-17-15-38)19-23-18-24(5-6-26(23)30)37-28-25-8-11-40(20-22(25)7-10-35-28)29-27(31(32,33)34)4-3-9-36-29;1-31(2)21-38(16-6-5-15-37-13-3-4-14-37)19-23-18-24(9-10-26(23)31)36-29-25-11-17-39(20-28(25)34-22-35-29)30-27(32)8-7-12-33-30;1-30(2)20-38(16-15-37-13-11-36(3)12-14-37)18-22-17-23(6-7-25(22)30)35-28-24-8-10-39(19-27(24)33-21-34-28)29-26(31)5-4-9-32-29;1-28(2)19-34(15-14-33(3)4)17-21-16-22(7-8-24(21)28)32-26-23-10-13-35(18-20(23)9-12-30-26)27-25(29)6-5-11-31-27/h7-11,13-14,20H,3-6,12,15-19,21-23H2,1-2H3,(H,34,36);7,9-11,13,19,23H,4-6,8,12,14-18,20-22H2,1-3H3,(H,34,35,36);3-7,9-10,18H,8,11-17,19-21H2,1-2H3,(H,35,37);7-10,12,18,22H,3-6,11,13-17,19-21H2,1-2H3,(H,34,35,36);4-7,9,17,21H,8,10-16,18-20H2,1-3H3,(H,33,34,35);5-9,11-12,16H,10,13-15,17-19H2,1-4H3,(H,30,32).

What are the key properties of 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine?

6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine has a molecular weight of 3253.14 g/mol, XLogP of 30.22, 42 rotatable bonds, 6 hydrogen bond donors, and 43 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-chloro-2-pyridinyl)-N-[2-[2-(dimethylamino)ethyl]-4,4-dimethyl-1,3-dihydroisoquinolin-7-yl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;7-(3-chloro-2-pyridinyl)-N-[4,4-dimethyl-2-[2-(4-methylpiperazin-1-yl)ethyl]-1,3-dihydroisoquinolin-7-yl]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(2-morpholin-4-ylethyl)-1,3-dihydroisoquinolin-7-yl]-6-[3-(trifluoromethyl)-2-pyridinyl]-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(3-piperidin-1-ylpropyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-methylsulfonyl-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-6-(3-fluoro-2-pyridinyl)-7,8-dihydro-5H-2,6-naphthyridin-1-amine;N-[4,4-dimethyl-2-(4-pyrrolidin-1-ylbutyl)-1,3-dihydroisoquinolin-7-yl]-7-(3-fluoro-2-pyridinyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-amine is sourced from PubChem (CID 159896777), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).