4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen

C125H144Cl7F3N46O7 — CID 159925195

About 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen

4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen (PubChem CID 159925195) has the molecular formula C125H144Cl7F3N46O7 and a molecular weight of 2708.01 g/mol. Its IUPAC name is 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen.

Molecular Properties

• Compound Name: 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen
• PubChem CID: 159925195
• Molecular Formula: C125H144Cl7F3N46O7
• Molecular Weight: 2708.01 g/mol
• Exact Mass: 2703.01
• IUPAC Name: 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen
• SMILES: CC(NC(=O)COc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3Cl)n(C)n2)cc1)C(F)(F)F.CN1CCN(Cc2cccc(-c3nc(Nc4ccc5[nH]ncc5c4Cl)n(C)n3)c2)CC1.CN1CCc2cc(-c3nc(Nc4ccc5[nH]ncc5c4Cl)n(C)n3)ccc2C1=O.COc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3Cl)n(C)n2)cc1.Cn1nc(-c2cccc(O)c2)nc1Nc1ccc2[nH]ncc2c1Cl.Cn1nc(-c2ccco2)nc1Nc1ccc2[nH]ncc2c1Cl.Cn1nc(C2=CCOCC2)nc1Nc1ccc2[nH]ncc2c1Cl.[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H]
• InChI: InChI=1S/C22H25ClN8.C21H19ClF3N7O2.C20H18ClN7O.C17H15ClN6O.C16H13ClN6O.C15H15ClN6O.C14H11ClN6O.14H2/c1-29-8-10-31(11-9-29)14-15-4-3-5-16(12-15)21-26-22(30(2)28-21)25-19-7-6-18-17(20(19)23)13-24-27-18;1-11(21(23,24)25)27-17(33)10-34-13-5-3-12(4-6-13)19-29-20(32(2)31-19)28-16-8-7-15-14(18(16)22)9-26-30-15;1-27-8-7-11-9-12(3-4-13(11)19(27)29)18-24-20(28(2)26-18)23-16-6-5-15-14(17(16)21)10-22-25-15;1-24-17(20-14-8-7-13-12(15(14)18)9-19-22-13)21-16(23-24)10-3-5-11(25-2)6-4-10;1-23-16(20-15(22-23)9-3-2-4-10(24)7-9)19-13-6-5-12-11(14(13)17)8-18-21-12;1-22-15(19-14(21-22)9-4-6-23-7-5-9)18-12-3-2-11-10(13(12)16)8-17-20-11;1-21-14(18-13(20-21)11-3-2-6-22-11)17-10-5-4-9-8(12(10)15)7-16-19-9;;;;;;;;;;;;;;/h3-7,12-13H,8-11,14H2,1-2H3,(H,24,27)(H,25,26,28);3-9,11H,10H2,1-2H3,(H,26,30)(H,27,33)(H,28,29,31);3-6,9-10H,7-8H2,1-2H3,(H,22,25)(H,23,24,26);3-9H,1-2H3,(H,19,22)(H,20,21,23);2-8,24H,1H3,(H,18,21)(H,19,20,22);2-4,8H,5-7H2,1H3,(H,17,20)(H,18,19,21);2-7H,1H3,(H,16,19)(H,17,18,20);14*1H
• InChIKey: NYXRATURNMRXJJ-UHFFFAOYSA-N
• XLogP: 28.00
• TPSA: 616.89 Ų
• H-Bond Donors: 16
• H-Bond Acceptors: 44
• Rotatable Bonds: 28
• Heavy Atoms: 188
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2708.01
LogP ≤ 5	28.00
H-Bond Donors ≤ 5	16
H-Bond Acceptors ≤ 10	44

Frequently Asked Questions

What is the IUPAC name of 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen?

The IUPAC name of 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen (CID 159925195) is 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen.

What is the SMILES notation for 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen?

The canonical SMILES for 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen is CC(NC(=O)COc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3Cl)n(C)n2)cc1)C(F)(F)F.CN1CCN(Cc2cccc(-c3nc(Nc4ccc5[nH]ncc5c4Cl)n(C)n3)c2)CC1.CN1CCc2cc(-c3nc(Nc4ccc5[nH]ncc5c4Cl)n(C)n3)ccc2C1=O.COc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3Cl)n(C)n2)cc1.Cn1nc(-c2cccc(O)c2)nc1Nc1ccc2[nH]ncc2c1Cl.Cn1nc(-c2ccco2)nc1Nc1ccc2[nH]ncc2c1Cl.Cn1nc(C2=CCOCC2)nc1Nc1ccc2[nH]ncc2c1Cl.[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].[H][H].

What is the InChIKey of 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen?

The InChIKey is NYXRATURNMRXJJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25ClN8.C21H19ClF3N7O2.C20H18ClN7O.C17H15ClN6O.C16H13ClN6O.C15H15ClN6O.C14H11ClN6O.14H2/c1-29-8-10-31(11-9-29)14-15-4-3-5-16(12-15)21-26-22(30(2)28-21)25-19-7-6-18-17(20(19)23)13-24-27-18;1-11(21(23,24)25)27-17(33)10-34-13-5-3-12(4-6-13)19-29-20(32(2)31-19)28-16-8-7-15-14(18(16)22)9-26-30-15;1-27-8-7-11-9-12(3-4-13(11)19(27)29)18-24-20(28(2)26-18)23-16-6-5-15-14(17(16)21)10-22-25-15;1-24-17(20-14-8-7-13-12(15(14)18)9-19-22-13)21-16(23-24)10-3-5-11(25-2)6-4-10;1-23-16(20-15(22-23)9-3-2-4-10(24)7-9)19-13-6-5-12-11(14(13)17)8-18-21-12;1-22-15(19-14(21-22)9-4-6-23-7-5-9)18-12-3-2-11-10(13(12)16)8-17-20-11;1-21-14(18-13(20-21)11-3-2-6-22-11)17-10-5-4-9-8(12(10)15)7-16-19-9;;;;;;;;;;;;;;/h3-7,12-13H,8-11,14H2,1-2H3,(H,24,27)(H,25,26,28);3-9,11H,10H2,1-2H3,(H,26,30)(H,27,33)(H,28,29,31);3-6,9-10H,7-8H2,1-2H3,(H,22,25)(H,23,24,26);3-9H,1-2H3,(H,19,22)(H,20,21,23);2-8,24H,1H3,(H,18,21)(H,19,20,22);2-4,8H,5-7H2,1H3,(H,17,20)(H,18,19,21);2-7H,1H3,(H,16,19)(H,17,18,20);14*1H.

What are the key properties of 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen?

4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen has a molecular weight of 2708.01 g/mol, XLogP of 28.00, 28 rotatable bonds, 16 hydrogen bond donors, and 44 hydrogen bond acceptors.

Where does this data come from?

All data for 4-chloro-N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[5-(furan-2-yl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;6-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]-2-methyl-3,4-dihydroisoquinolin-1-one;3-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenol;2-[4-[5-[(4-chloro-1H-indazol-5-yl)amino]-1-methyl-1,2,4-triazol-3-yl]phenoxy]-N-(1,1,1-trifluoropropan-2-yl)acetamide;4-chloro-N-[5-(4-methoxyphenyl)-2-methyl-1,2,4-triazol-3-yl]-1H-indazol-5-amine;4-chloro-N-[2-methyl-5-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]-1,2,4-triazol-3-yl]-1H-indazol-5-amine;molecular hydrogen is sourced from PubChem (CID 159925195), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).