1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine

C202H218F2N32O13S7 — CID 159925944

About 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine

1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine (PubChem CID 159925944) has the molecular formula C202H218F2N32O13S7 and a molecular weight of 3564.64 g/mol. Its IUPAC name is 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine.

Molecular Properties

• Compound Name: 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine
• PubChem CID: 159925944
• Molecular Formula: C202H218F2N32O13S7
• Molecular Weight: 3564.64 g/mol
• Exact Mass: 3561.54
• IUPAC Name: 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine
• SMILES: CC(C)(C)C#Cc1cccc(COc2cc(-c3cnc(Cc4ccccc4)s3)cnc2N)c1.CC(C)(C)C#Cc1cccc(COc2cc(-c3cnc(S(C)(=O)=O)s3)cnc2N)c1.CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC5(O)CC5)ccc4F)c3)s2)CC1.CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)C)c4)c3)s2)CC1.CN1CCC(n2cc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)C)c4)c3)cn2)CC1.CSc1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)C)c3)c2)s1.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1OCc1cc(C#CC2(O)CC2)ccc1F.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1OCc1cccc(C#CC2(O)CC2)c1
• InChI: InChI=1S/C28H27N3OS.C27H33N5O.C27H32N4OS.C26H27FN4O2S.C25H26FN5O2.C25H27N5O2.C22H23N3O3S2.C22H23N3OS2/c1-28(2,3)13-12-21-10-7-11-22(14-21)19-32-24-16-23(17-31-27(24)29)25-18-30-26(33-25)15-20-8-5-4-6-9-20;1-27(2,3)11-8-20-6-5-7-21(14-20)19-33-25-15-22(16-29-26(25)28)23-17-30-32(18-23)24-9-12-31(4)13-10-24;1-27(2,3)11-8-19-6-5-7-20(14-19)18-32-23-15-22(16-29-25(23)28)24-17-30-26(33-24)21-9-12-31(4)13-10-21;1-31-10-5-18(6-11-31)25-30-15-23(34-25)19-13-22(24(28)29-14-19)33-16-20-12-17(2-3-21(20)27)4-7-26(32)8-9-26;26-22-2-1-17(3-6-25(32)7-8-25)11-19(22)16-33-23-12-18(13-29-24(23)27)20-14-30-31(15-20)21-4-9-28-10-5-21;26-24-23(32-17-19-3-1-2-18(12-19)4-7-25(31)8-9-25)13-20(14-28-24)21-15-29-30(16-21)22-5-10-27-11-6-22;1-22(2,3)9-8-15-6-5-7-16(10-15)14-28-18-11-17(12-24-20(18)23)19-13-25-21(29-19)30(4,26)27;1-22(2,3)9-8-15-6-5-7-16(10-15)14-26-18-11-17(12-24-20(18)23)19-13-25-21(27-4)28-19/h4-11,14,16-18H,15,19H2,1-3H3,(H2,29,31);5-7,14-18,24H,9-10,12-13,19H2,1-4H3,(H2,28,29);5-7,14-17,21H,9-10,12-13,18H2,1-4H3,(H2,28,29);2-3,12-15,18,32H,5-6,8-11,16H2,1H3,(H2,28,29);1-2,11-15,21,28,32H,4-5,7-10,16H2,(H2,27,29);1-3,12-16,22,27,31H,5-6,8-11,17H2,(H2,26,28);5-7,10-13H,14H2,1-4H3,(H2,23,24);5-7,10-13H,14H2,1-4H3,(H2,23,24)
• InChIKey: NYZZRQHYTLZFPZ-UHFFFAOYSA-N
• XLogP: 36.50
• TPSA: 631.64 Ų
• H-Bond Donors: 13
• H-Bond Acceptors: 51
• Rotatable Bonds: 41
• Heavy Atoms: 256
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	3564.64
LogP ≤ 5	36.50
H-Bond Donors ≤ 5	13
H-Bond Acceptors ≤ 10	51

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_OC_no_alk_C(3)', 'substructure': 'N/A'}, {'alert_name': 'thiazol_SC_A(3)', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine?

The IUPAC name of 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine (CID 159925944) is 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine.

What is the SMILES notation for 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine?

The canonical SMILES for 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine is CC(C)(C)C#Cc1cccc(COc2cc(-c3cnc(Cc4ccccc4)s3)cnc2N)c1.CC(C)(C)C#Cc1cccc(COc2cc(-c3cnc(S(C)(=O)=O)s3)cnc2N)c1.CN1CCC(c2ncc(-c3cnc(N)c(OCc4cc(C#CC5(O)CC5)ccc4F)c3)s2)CC1.CN1CCC(c2ncc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)C)c4)c3)s2)CC1.CN1CCC(n2cc(-c3cnc(N)c(OCc4cccc(C#CC(C)(C)C)c4)c3)cn2)CC1.CSc1ncc(-c2cnc(N)c(OCc3cccc(C#CC(C)(C)C)c3)c2)s1.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1OCc1cc(C#CC2(O)CC2)ccc1F.Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1OCc1cccc(C#CC2(O)CC2)c1.

What is the InChIKey of 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine?

The InChIKey is NYZZRQHYTLZFPZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H27N3OS.C27H33N5O.C27H32N4OS.C26H27FN4O2S.C25H26FN5O2.C25H27N5O2.C22H23N3O3S2.C22H23N3OS2/c1-28(2,3)13-12-21-10-7-11-22(14-21)19-32-24-16-23(17-31-27(24)29)25-18-30-26(33-25)15-20-8-5-4-6-9-20;1-27(2,3)11-8-20-6-5-7-21(14-20)19-33-25-15-22(16-29-26(25)28)23-17-30-32(18-23)24-9-12-31(4)13-10-24;1-27(2,3)11-8-19-6-5-7-20(14-19)18-32-23-15-22(16-29-25(23)28)24-17-30-26(33-24)21-9-12-31(4)13-10-21;1-31-10-5-18(6-11-31)25-30-15-23(34-25)19-13-22(24(28)29-14-19)33-16-20-12-17(2-3-21(20)27)4-7-26(32)8-9-26;26-22-2-1-17(3-6-25(32)7-8-25)11-19(22)16-33-23-12-18(13-29-24(23)27)20-14-30-31(15-20)21-4-9-28-10-5-21;26-24-23(32-17-19-3-1-2-18(12-19)4-7-25(31)8-9-25)13-20(14-28-24)21-15-29-30(16-21)22-5-10-27-11-6-22;1-22(2,3)9-8-15-6-5-7-16(10-15)14-28-18-11-17(12-24-20(18)23)19-13-25-21(29-19)30(4,26)27;1-22(2,3)9-8-15-6-5-7-16(10-15)14-26-18-11-17(12-24-20(18)23)19-13-25-21(27-4)28-19/h4-11,14,16-18H,15,19H2,1-3H3,(H2,29,31);5-7,14-18,24H,9-10,12-13,19H2,1-4H3,(H2,28,29);5-7,14-17,21H,9-10,12-13,18H2,1-4H3,(H2,28,29);2-3,12-15,18,32H,5-6,8-11,16H2,1H3,(H2,28,29);1-2,11-15,21,28,32H,4-5,7-10,16H2,(H2,27,29);1-3,12-16,22,27,31H,5-6,8-11,17H2,(H2,26,28);5-7,10-13H,14H2,1-4H3,(H2,23,24);5-7,10-13H,14H2,1-4H3,(H2,23,24).

What are the key properties of 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine?

1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine has a molecular weight of 3564.64 g/mol, XLogP of 36.50, 41 rotatable bonds, 13 hydrogen bond donors, and 51 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[2-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]-4-fluorophenyl]ethynyl]cyclopropan-1-ol;1-[2-[3-[[2-amino-5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]oxymethyl]phenyl]ethynyl]cyclopropan-1-ol;5-(2-benzyl-1,3-thiazol-5-yl)-3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfanyl-1,3-thiazol-5-yl)pyridin-2-amine;3-[[3-(3,3-dimethylbut-1-ynyl)phenyl]methoxy]-5-(2-methylsulfonyl-1,3-thiazol-5-yl)pyridin-2-amine is sourced from PubChem (CID 159925944), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).