[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone

C171H165F6N25O17 — CID 159931948

IUPAC[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
SMILESCC(F)(F)c1cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)ccc1F.COCc1ccccc1C(=O)N1CCn2nc(OCc3ccccc3)cc2C1.Cc1cc(C#N)cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)c1.Cc1ccc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)cc1F.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C(C)C2)cc1.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C[C@H]2C)cc1.O=C(c1c(F)cccc1F)N1CCn2nc(OCc3ccccc3)cc2C1.O=C(c1ccccc1)N1CCn2nc(OCc3ccccc3)cc2C1
InChIInChI=1S/C22H20F3N3O2.C22H20N4O2.C22H23N3O3.2C22H23N3O2.C21H20FN3O2.C20H17F2N3O2.C20H19N3O2/c1-22(24,25)18-11-16(7-8-19(18)23)21(29)27-9-10-28-17(13-27)12-20(26-28)30-14-15-5-3-2-4-6-15;1-16-9-18(13-23)11-19(10-16)22(27)25-7-8-26-20(14-25)12-21(24-26)28-15-17-5-3-2-4-6-17;1-27-16-18-9-5-6-10-20(18)22(26)24-11-12-25-19(14-24)13-21(23-25)28-15-17-7-3-2-4-8-17;1-16-8-10-19(11-9-16)22(26)24-14-20-12-21(23-25(20)13-17(24)2)27-15-18-6-4-3-5-7-18;1-16-8-10-19(11-9-16)22(26)24-13-17(2)25-20(14-24)12-21(23-25)27-15-18-6-4-3-5-7-18;1-15-7-8-17(11-19(15)22)21(26)24-9-10-25-18(13-24)12-20(23-25)27-14-16-5-3-2-4-6-16;21-16-7-4-8-17(22)19(16)20(26)24-9-10-25-15(12-24)11-18(23-25)27-13-14-5-2-1-3-6-14;24-20(17-9-5-2-6-10-17)22-11-12-23-18(14-22)13-19(21-23)25-15-16-7-3-1-4-8-16/h2-8,11-12H,9-10,13-14H2,1H3;2-6,9-12H,7-8,14-15H2,1H3;2-10,13H,11-12,14-16H2,1H3;2*3-12,17H,13-15H2,1-2H3;2-8,11-12H,9-10,13-14H2,1H3;1-8,11H,9-10,12-13H2;1-10,13H,11-12,14-15H2/t;;;17-;;;;/m...1..../s1
InChIKeyNZTGQKQTVJLYEC-LFSHGRIRSA-N
MW2956.35 g/mol
LogP28.81
Rot. Bonds35

About [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone

[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone (PubChem CID 159931948) has the molecular formula C171H165F6N25O17 and a molecular weight of 2956.35 g/mol. Its IUPAC name is [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone.

Molecular Properties

Compound Name[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
PubChem CID159931948
Molecular FormulaC171H165F6N25O17
Molecular Weight2956.35 g/mol
Exact Mass2954.27
IUPAC Name[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
SMILESCC(F)(F)c1cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)ccc1F.COCc1ccccc1C(=O)N1CCn2nc(OCc3ccccc3)cc2C1.Cc1cc(C#N)cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)c1.Cc1ccc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)cc1F.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C(C)C2)cc1.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C[C@H]2C)cc1.O=C(c1c(F)cccc1F)N1CCn2nc(OCc3ccccc3)cc2C1.O=C(c1ccccc1)N1CCn2nc(OCc3ccccc3)cc2C1
InChIInChI=1S/C22H20F3N3O2.C22H20N4O2.C22H23N3O3.2C22H23N3O2.C21H20FN3O2.C20H17F2N3O2.C20H19N3O2/c1-22(24,25)18-11-16(7-8-19(18)23)21(29)27-9-10-28-17(13-27)12-20(26-28)30-14-15-5-3-2-4-6-15;1-16-9-18(13-23)11-19(10-16)22(27)25-7-8-26-20(14-25)12-21(24-26)28-15-17-5-3-2-4-6-17;1-27-16-18-9-5-6-10-20(18)22(26)24-11-12-25-19(14-24)13-21(23-25)28-15-17-7-3-2-4-8-17;1-16-8-10-19(11-9-16)22(26)24-14-20-12-21(23-25(20)13-17(24)2)27-15-18-6-4-3-5-7-18;1-16-8-10-19(11-9-16)22(26)24-13-17(2)25-20(14-24)12-21(23-25)27-15-18-6-4-3-5-7-18;1-15-7-8-17(11-19(15)22)21(26)24-9-10-25-18(13-24)12-20(23-25)27-14-16-5-3-2-4-6-16;21-16-7-4-8-17(22)19(16)20(26)24-9-10-25-15(12-24)11-18(23-25)27-13-14-5-2-1-3-6-14;24-20(17-9-5-2-6-10-17)22-11-12-23-18(14-22)13-19(21-23)25-15-16-7-3-1-4-8-16/h2-8,11-12H,9-10,13-14H2,1H3;2-6,9-12H,7-8,14-15H2,1H3;2-10,13H,11-12,14-16H2,1H3;2*3-12,17H,13-15H2,1-2H3;2-8,11-12H,9-10,13-14H2,1H3;1-8,11H,9-10,12-13H2;1-10,13H,11-12,14-15H2/t;;;17-;;;;/m...1..../s1
InChIKeyNZTGQKQTVJLYEC-LFSHGRIRSA-N
XLogP28.81
TPSA411.90 Ų
H-Bond Donors
H-Bond Acceptors34
Rotatable Bonds35
Heavy Atoms219
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002956.35
LogP ≤ 528.81
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1034

Analyze [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone with MolForge

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Related Compounds

[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(1,1-difluoroethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 157118261
4-[2-(azetidine-1-carbonyl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-3-yl]-2-fluoro-5-methylbenzonitrile;azetidin-1-yl-[3-(4-chlorophenyl)-5-methyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-2-yl]methanone;3-(4-cyano-2,5-difluorophenyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;3-(4-cyano-5-fluoro-2-methylphenyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;3-(4-cyanophenyl)-N-cyclopropyl-6,6-difluoro-5,7-dihydropyrazolo[5,1-b][1,3]oxazine-2-carboxamide
CID 157495388
2-bicyclo[2.2.1]heptanyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-chlorophenyl)-[2-[(4-fluorophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(2,5-difluorophenyl)-[2-[(3-fluorophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(2-fluoro-3-methylphenyl)-[2-[(3-fluorophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(3-fluoro-5-methylphenyl)-[2-[(3-fluorophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(3-fluorophenyl)-[2-[(4-isocyanophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;[2-[(4-isocyanophenyl)methoxy]-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]-phenylmethanone;[4-methyl-3-(trifluoromethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone
CID 157575243
azetidin-1-yl-[3-(5-methyl-3-pyridinyl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-2-yl]methanone;3-(4-cyano-2-fluorophenyl)-N-propan-2-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;3-(5-cyano-2-methylphenyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;3-(5-cyano-2-pyridinyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;N-cyclopropyl-3-[5-(trifluoromethyl)-3-pyridinyl]-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide
CID 157606852
3,3-difluoro-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)butan-1-one;2-(2,2-difluoropropoxy)-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;3,3-dimethyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)butan-1-one;bis(4,4-dimethyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)pentan-1-one);2-(2,2-dimethylpropoxy)-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;2-ethoxy-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;2-[(2-methylpropan-2-yl)oxy]-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)-2-propan-2-yloxyethanone
CID 157775462
(3-chloro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-chlorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(1,1-difluoroethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;methane;(3-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone
CID 158198778
(6R)-5-benzyl-6-methyl-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-benzyl-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-7,8-dihydro-6H-pyrazolo[1,5-a][1,4]diazepin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(3-fluoro-3-methylcyclobutyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(3-fluoro-5-methylphenyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-[(1-methylcyclobutyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
CID 158428553
3-(4-chloro-2,5-difluorophenyl)-N-cyclopropyl-6,6-difluoro-5,7-dihydropyrazolo[5,1-b][1,3]oxazine-2-carboxamide;(6R)-3-(4-chloro-5-fluoro-2-methylphenyl)-N-cyclopropyl-6-fluoro-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;(6S)-3-(4-chloro-5-fluoro-2-methylphenyl)-N-cyclopropyl-6-fluoro-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;(6S)-3-(4-cyano-5-fluoro-2-methylphenyl)-N-cyclopropyl-6-fluoro-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide;3-(5-cyano-2-methylphenyl)-N-cyclopropyl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide
CID 158440414
(3-chloro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2-chlorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(1,1-difluoroethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-[(3-fluorophenyl)methoxy]-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl]-(4-methylphenyl)methanone;methane;(3-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(4-methylphenyl)-(2-phenylmethoxy-4,6,7,8-tetrahydropyrazolo[1,5-a][1,4]diazepin-5-yl)methanone
CID 158542489
5-(cyclobutylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(cyclopropylmethyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;5-(2,2-difluoropropyl)-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;2-[(3-fluorophenyl)methoxy]-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one;2-[(4-fluorophenyl)methoxy]-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one;5-[(1-methylcyclobutyl)methyl]-2-phenylmethoxy-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one;(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one;7-methyl-2-phenylmethoxy-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one;2-phenylmethoxy-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one
CID 158562123
3,3-difluoro-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)butan-1-one;4,4-difluoro-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)pentan-1-one;bis(4,4-dimethyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)pentan-1-one);2-ethoxy-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;(2-phenylcyclopropyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone
CID 158578143
2,2-dimethyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)propan-1-one;2-methyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)butan-1-one;2-phenylmethoxy-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)ethanone;(2S)-3,3,3-trifluoro-2-methoxy-2-phenyl-1-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)propan-1-one
CID 158709471

Frequently Asked Questions

What is the IUPAC name of [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone?
The IUPAC name of [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone (CID 159931948) is [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone.
What is the SMILES notation for [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone?
The canonical SMILES for [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone is CC(F)(F)c1cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)ccc1F.COCc1ccccc1C(=O)N1CCn2nc(OCc3ccccc3)cc2C1.Cc1cc(C#N)cc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)c1.Cc1ccc(C(=O)N2CCn3nc(OCc4ccccc4)cc3C2)cc1F.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C(C)C2)cc1.Cc1ccc(C(=O)N2Cc3cc(OCc4ccccc4)nn3C[C@H]2C)cc1.O=C(c1c(F)cccc1F)N1CCn2nc(OCc3ccccc3)cc2C1.O=C(c1ccccc1)N1CCn2nc(OCc3ccccc3)cc2C1.
What is the InChIKey of [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone?
The InChIKey is NZTGQKQTVJLYEC-LFSHGRIRSA-N. The full InChI is InChI=1S/C22H20F3N3O2.C22H20N4O2.C22H23N3O3.2C22H23N3O2.C21H20FN3O2.C20H17F2N3O2.C20H19N3O2/c1-22(24,25)18-11-16(7-8-19(18)23)21(29)27-9-10-28-17(13-27)12-20(26-28)30-14-15-5-3-2-4-6-15;1-16-9-18(13-23)11-19(10-16)22(27)25-7-8-26-20(14-25)12-21(24-26)28-15-17-5-3-2-4-6-17;1-27-16-18-9-5-6-10-20(18)22(26)24-11-12-25-19(14-24)13-21(23-25)28-15-17-7-3-2-4-8-17;1-16-8-10-19(11-9-16)22(26)24-14-20-12-21(23-25(20)13-17(24)2)27-15-18-6-4-3-5-7-18;1-16-8-10-19(11-9-16)22(26)24-13-17(2)25-20(14-24)12-21(23-25)27-15-18-6-4-3-5-7-18;1-15-7-8-17(11-19(15)22)21(26)24-9-10-25-18(13-24)12-20(23-25)27-14-16-5-3-2-4-6-16;21-16-7-4-8-17(22)19(16)20(26)24-9-10-25-15(12-24)11-18(23-25)27-13-14-5-2-1-3-6-14;24-20(17-9-5-2-6-10-17)22-11-12-23-18(14-22)13-19(21-23)25-15-16-7-3-1-4-8-16/h2-8,11-12H,9-10,13-14H2,1H3;2-6,9-12H,7-8,14-15H2,1H3;2-10,13H,11-12,14-16H2,1H3;2*3-12,17H,13-15H2,1-2H3;2-8,11-12H,9-10,13-14H2,1H3;1-8,11H,9-10,12-13H2;1-10,13H,11-12,14-15H2/t;;;17-;;;;/m...1..../s1.
What are the key properties of [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone?
[3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone has a molecular weight of 2956.35 g/mol, XLogP of 28.81, 35 rotatable bonds, 0 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for [3-(1,1-difluoroethyl)-4-fluorophenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(2,6-difluorophenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;(3-fluoro-4-methylphenyl)-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;[2-(methoxymethyl)phenyl]-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;3-methyl-5-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carbonyl)benzonitrile;(4-methylphenyl)-[(6R)-6-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl]methanone;(4-methylphenyl)-(7-methyl-2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone;phenyl-(2-phenylmethoxy-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazin-5-yl)methanone is sourced from PubChem (CID 159931948), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).