N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide

C81H53F8N17O4S — CID 159937072

IUPACN-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide
SMILESO=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cccs1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1ccncc1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cnccn1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cncnc1
InChIInChI=1S/C21H14F2N4O.2C20H13F2N5O.C20H13F2N3OS/c22-15-4-1-13(2-5-15)3-6-18-16-11-20(17(23)12-19(16)27-26-18)25-21(28)14-7-9-24-10-8-14;21-14-4-1-12(2-5-14)3-6-17-15-7-19(16(22)8-18(15)27-26-17)25-20(28)13-9-23-11-24-10-13;21-13-4-1-12(2-5-13)3-6-16-14-9-18(15(22)10-17(14)27-26-16)25-20(28)19-11-23-7-8-24-19;21-13-6-3-12(4-7-13)5-8-16-14-10-18(15(22)11-17(14)25-24-16)23-20(26)19-2-1-9-27-19/h1-12H,(H,25,28)(H,26,27);2*1-11H,(H,25,28)(H,26,27);1-11H,(H,23,26)(H,24,25)/b3*6-3+;8-5+
InChIKeyOAJSHMQLDMXKGQ-WMAKJJNXSA-N
MW1512.48 g/mol
LogP18.09
Rot. Bonds16

About N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide

N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide (PubChem CID 159937072) has the molecular formula C81H53F8N17O4S and a molecular weight of 1512.48 g/mol. Its IUPAC name is N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide.

Molecular Properties

Compound NameN-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide
PubChem CID159937072
Molecular FormulaC81H53F8N17O4S
Molecular Weight1512.48 g/mol
Exact Mass1511.41
IUPAC NameN-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide
SMILESO=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cccs1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1ccncc1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cnccn1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cncnc1
InChIInChI=1S/C21H14F2N4O.2C20H13F2N5O.C20H13F2N3OS/c22-15-4-1-13(2-5-15)3-6-18-16-11-20(17(23)12-19(16)27-26-18)25-21(28)14-7-9-24-10-8-14;21-14-4-1-12(2-5-14)3-6-17-15-7-19(16(22)8-18(15)27-26-17)25-20(28)13-9-23-11-24-10-13;21-13-4-1-12(2-5-13)3-6-16-14-9-18(15(22)10-17(14)27-26-16)25-20(28)19-11-23-7-8-24-19;21-13-6-3-12(4-7-13)5-8-16-14-10-18(15(22)11-17(14)25-24-16)23-20(26)19-2-1-9-27-19/h1-12H,(H,25,28)(H,26,27);2*1-11H,(H,25,28)(H,26,27);1-11H,(H,23,26)(H,24,25)/b3*6-3+;8-5+
InChIKeyOAJSHMQLDMXKGQ-WMAKJJNXSA-N
XLogP18.09
TPSA295.57 Ų
H-Bond Donors8
H-Bond Acceptors14
Rotatable Bonds16
Heavy Atoms111
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001512.48
LogP ≤ 518.09
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1014

Analyze N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide?
The IUPAC name of N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide (CID 159937072) is N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide.
What is the SMILES notation for N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide?
The canonical SMILES for N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide is O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cccs1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1ccncc1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cnccn1.O=C(Nc1cc2c(/C=C/c3ccc(F)cc3)n[nH]c2cc1F)c1cncnc1.
What is the InChIKey of N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide?
The InChIKey is OAJSHMQLDMXKGQ-WMAKJJNXSA-N. The full InChI is InChI=1S/C21H14F2N4O.2C20H13F2N5O.C20H13F2N3OS/c22-15-4-1-13(2-5-15)3-6-18-16-11-20(17(23)12-19(16)27-26-18)25-21(28)14-7-9-24-10-8-14;21-14-4-1-12(2-5-14)3-6-17-15-7-19(16(22)8-18(15)27-26-17)25-20(28)13-9-23-11-24-10-13;21-13-4-1-12(2-5-13)3-6-16-14-9-18(15(22)10-17(14)27-26-16)25-20(28)19-11-23-7-8-24-19;21-13-6-3-12(4-7-13)5-8-16-14-10-18(15(22)11-17(14)25-24-16)23-20(26)19-2-1-9-27-19/h1-12H,(H,25,28)(H,26,27);2*1-11H,(H,25,28)(H,26,27);1-11H,(H,23,26)(H,24,25)/b3*6-3+;8-5+.
What are the key properties of N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide?
N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide has a molecular weight of 1512.48 g/mol, XLogP of 18.09, 16 rotatable bonds, 8 hydrogen bond donors, and 14 hydrogen bond acceptors.
Where does this data come from?
All data for N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrazine-2-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyridine-4-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]pyrimidine-5-carboxamide;N-[6-fluoro-3-[(E)-2-(4-fluorophenyl)ethenyl]-1H-indazol-5-yl]thiophene-2-carboxamide is sourced from PubChem (CID 159937072), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).