N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide

C74H73N27O7S — CID 159940522

About N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide

N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide (PubChem CID 159940522) has the molecular formula C74H73N27O7S and a molecular weight of 1484.65 g/mol. Its IUPAC name is N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide.

Molecular Properties

• Compound Name: N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide
• PubChem CID: 159940522
• Molecular Formula: C74H73N27O7S
• Molecular Weight: 1484.65 g/mol
• Exact Mass: 1483.59
• IUPAC Name: N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide
• SMILES: CC[C@H](Nc1nccc2[nH]cnc12)c1nc(-c2ccc(C(=O)NO)cc2)c2ccccc2n1.CC[C@H](Nc1nccc2[nH]cnc12)c1nc(N2CCN(c3nc(C(=O)NO)co3)CC2)c2ccccc2n1.CC[C@H](Nc1nccc2[nH]cnc12)c1nc(N2CCN(c3nc(C(=O)NO)cs3)CC2)c2ccccc2n1
• InChI: InChI=1S/C25H26N10O3.C25H26N10O2S.C24H21N7O2/c2*1-2-16(29-22-20-18(7-8-26-22)27-14-28-20)21-30-17-6-4-3-5-15(17)23(32-21)34-9-11-35(12-10-34)25-31-19(13-38-25)24(36)33-37;1-2-17(28-23-21-19(11-12-25-23)26-13-27-21)22-29-18-6-4-3-5-16(18)20(30-22)14-7-9-15(10-8-14)24(32)31-33/h2*3-8,13-14,16,37H,2,9-12H2,1H3,(H,26,29)(H,27,28)(H,33,36);3-13,17,33H,2H2,1H3,(H,25,28)(H,26,27)(H,31,32)/t2*16-;17-/m000/s1
• InChIKey: OAUWZNDUDQEULE-WOCUFWBTSA-N
• XLogP: 10.51
• TPSA: 438.01 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 29
• Rotatable Bonds: 20
• Heavy Atoms: 109
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1484.65
LogP ≤ 5	10.51
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	29

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide?

The IUPAC name of N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide (CID 159940522) is N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide.

What is the SMILES notation for N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide?

The canonical SMILES for N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide is CC[C@H](Nc1nccc2[nH]cnc12)c1nc(-c2ccc(C(=O)NO)cc2)c2ccccc2n1.CC[C@H](Nc1nccc2[nH]cnc12)c1nc(N2CCN(c3nc(C(=O)NO)co3)CC2)c2ccccc2n1.CC[C@H](Nc1nccc2[nH]cnc12)c1nc(N2CCN(c3nc(C(=O)NO)cs3)CC2)c2ccccc2n1.

What is the InChIKey of N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide?

The InChIKey is OAUWZNDUDQEULE-WOCUFWBTSA-N. The full InChI is InChI=1S/C25H26N10O3.C25H26N10O2S.C24H21N7O2/c2*1-2-16(29-22-20-18(7-8-26-22)27-14-28-20)21-30-17-6-4-3-5-15(17)23(32-21)34-9-11-35(12-10-34)25-31-19(13-38-25)24(36)33-37;1-2-17(28-23-21-19(11-12-25-23)26-13-27-21)22-29-18-6-4-3-5-16(18)20(30-22)14-7-9-15(10-8-14)24(32)31-33/h2*3-8,13-14,16,37H,2,9-12H2,1H3,(H,26,29)(H,27,28)(H,33,36);3-13,17,33H,2H2,1H3,(H,25,28)(H,26,27)(H,31,32)/t2*16-;17-/m000/s1.

What are the key properties of N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide?

N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide has a molecular weight of 1484.65 g/mol, XLogP of 10.51, 20 rotatable bonds, 12 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for N-hydroxy-4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]benzamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-oxazole-4-carboxamide;N-hydroxy-2-[4-[2-[(1S)-1-(1H-imidazo[4,5-c]pyridin-4-ylamino)propyl]quinazolin-4-yl]piperazin-1-yl]-1,3-thiazole-4-carboxamide is sourced from PubChem (CID 159940522), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).