(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide

C122H143ClF3N25O13S2 — CID 159959701

About (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide

(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide (PubChem CID 159959701) has the molecular formula C122H143ClF3N25O13S2 and a molecular weight of 2324.23 g/mol. Its IUPAC name is (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide.

Molecular Properties

• Compound Name: (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide
• PubChem CID: 159959701
• Molecular Formula: C122H143ClF3N25O13S2
• Molecular Weight: 2324.23 g/mol
• Exact Mass: 2322.04
• IUPAC Name: (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide
• SMILES: CCC(O)(CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1)c1ccccc1.CCC(O)(CC(=O)Nc1nc2cccnc2n1C1CCC1)c1ccccc1.C[C@](O)(CC(=O)Nc1nc2cc(C3CC3)c(C(F)(F)F)nc2n1C1CCC1)c1ccccc1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3ccco3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3cccs3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3nccs3)n(C(C)(C)C)c2n1
• InChI: InChI=1S/C24H25F3N4O2.C21H23ClN4O2.C21H24N4O2.C19H24N4O3.C19H24N4O2S.C18H23N5O2S/c1-23(33,15-6-3-2-4-7-15)13-19(32)29-22-28-18-12-17(14-10-11-14)20(24(25,26)27)30-21(18)31(22)16-8-5-9-16;1-2-21(28,14-7-4-3-5-8-14)13-18(27)25-20-23-16-11-12-17(22)24-19(16)26(20)15-9-6-10-15;1-2-21(27,15-8-4-3-5-9-15)14-18(26)24-20-23-17-12-7-13-22-19(17)25(20)16-10-6-11-16;2*1-12-8-9-13-16(20-12)23(18(2,3)4)17(21-13)22-15(24)11-19(5,25)14-7-6-10-26-14;1-11-6-7-12-14(20-11)23(17(2,3)4)16(21-12)22-13(24)10-18(5,25)15-19-8-9-26-15/h2-4,6-7,12,14,16,33H,5,8-11,13H2,1H3,(H,28,29,32);3-5,7-8,11-12,15,28H,2,6,9-10,13H2,1H3,(H,23,25,27);3-5,7-9,12-13,16,27H,2,6,10-11,14H2,1H3,(H,23,24,26);2*6-10,25H,11H2,1-5H3,(H,21,22,24);6-9,25H,10H2,1-5H3,(H,21,22,24)/t23-;;;2*19-;18-/m0..000/s1
• InChIKey: ODEBTZZKISVFCX-YXFFTVEUSA-N
• XLogP: 23.81
• TPSA: 506.27 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 34
• Rotatable Bonds: 30
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2324.23
LogP ≤ 5	23.81
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	34

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide?

The IUPAC name of (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide (CID 159959701) is (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide.

What is the SMILES notation for (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide?

The canonical SMILES for (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide is CCC(O)(CC(=O)Nc1nc2ccc(Cl)nc2n1C1CCC1)c1ccccc1.CCC(O)(CC(=O)Nc1nc2cccnc2n1C1CCC1)c1ccccc1.C[C@](O)(CC(=O)Nc1nc2cc(C3CC3)c(C(F)(F)F)nc2n1C1CCC1)c1ccccc1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3ccco3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3cccs3)n(C(C)(C)C)c2n1.Cc1ccc2nc(NC(=O)C[C@](C)(O)c3nccs3)n(C(C)(C)C)c2n1.

What is the InChIKey of (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide?

The InChIKey is ODEBTZZKISVFCX-YXFFTVEUSA-N. The full InChI is InChI=1S/C24H25F3N4O2.C21H23ClN4O2.C21H24N4O2.C19H24N4O3.C19H24N4O2S.C18H23N5O2S/c1-23(33,15-6-3-2-4-7-15)13-19(32)29-22-28-18-12-17(14-10-11-14)20(24(25,26)27)30-21(18)31(22)16-8-5-9-16;1-2-21(28,14-7-4-3-5-8-14)13-18(27)25-20-23-16-11-12-17(22)24-19(16)26(20)15-9-6-10-15;1-2-21(27,15-8-4-3-5-9-15)14-18(26)24-20-23-17-12-7-13-22-19(17)25(20)16-10-6-11-16;2*1-12-8-9-13-16(20-12)23(18(2,3)4)17(21-13)22-15(24)11-19(5,25)14-7-6-10-26-14;1-11-6-7-12-14(20-11)23(17(2,3)4)16(21-12)22-13(24)10-18(5,25)15-19-8-9-26-15/h2-4,6-7,12,14,16,33H,5,8-11,13H2,1H3,(H,28,29,32);3-5,7-8,11-12,15,28H,2,6,9-10,13H2,1H3,(H,23,25,27);3-5,7-9,12-13,16,27H,2,6,10-11,14H2,1H3,(H,23,24,26);2*6-10,25H,11H2,1-5H3,(H,21,22,24);6-9,25H,10H2,1-5H3,(H,21,22,24)/t23-;;;2*19-;18-/m0..000/s1.

What are the key properties of (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide?

(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide has a molecular weight of 2324.23 g/mol, XLogP of 23.81, 30 rotatable bonds, 12 hydrogen bond donors, and 34 hydrogen bond acceptors.

Where does this data come from?

All data for (3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-(furan-2-yl)-3-hydroxybutanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-(1,3-thiazol-2-yl)butanamide;(3S)-N-(3-tert-butyl-5-methylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-thiophen-2-ylbutanamide;N-(5-chloro-3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide;(3S)-N-[3-cyclobutyl-6-cyclopropyl-5-(trifluoromethyl)imidazo[4,5-b]pyridin-2-yl]-3-hydroxy-3-phenylbutanamide;N-(3-cyclobutylimidazo[4,5-b]pyridin-2-yl)-3-hydroxy-3-phenylpentanamide is sourced from PubChem (CID 159959701), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).