N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide

C132H121Cl3F18N30O17S2 — CID 159980675

About N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide

N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide (PubChem CID 159980675) has the molecular formula C132H121Cl3F18N30O17S2 and a molecular weight of 2912.07 g/mol. Its IUPAC name is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide
• PubChem CID: 159980675
• Molecular Formula: C132H121Cl3F18N30O17S2
• Molecular Weight: 2912.07 g/mol
• Exact Mass: 2908.77
• IUPAC Name: N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide
• SMILES: CC(C)(C)Oc1ccc(NC(=O)c2cnc(N3CC[C@@H](O)C3)c(-c3cncnc3)c2)cc1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)c(OC)n1.O=C(Nc1ccc(C(F)(F)C(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)C(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(S(F)(F)(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(SC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1
• InChI: InChI=1S/C24H27N5O3.C23H22ClF2N5O5.C22H18ClF4N5O2.C22H18F5N5O3.C21H18ClF2N5O2S.C20H18F5N5O2S/c1-24(2,3)32-20-6-4-18(5-7-20)28-23(31)16-10-21(17-11-25-15-26-12-17)22(27-13-16)29-9-8-19(30)14-29;1-34-21-18(11-28-22(30-21)35-2)17-9-13(10-27-19(17)31-8-7-15(32)12-31)20(33)29-14-3-5-16(6-4-14)36-23(24,25)26;23-22(26,27)21(24,25)15-1-3-16(4-2-15)31-20(34)13-7-18(14-8-28-12-29-9-14)19(30-10-13)32-6-5-17(33)11-32;23-21(24,25)22(26,27)35-17-3-1-15(2-4-17)31-20(34)13-7-18(14-8-28-12-29-9-14)19(30-10-13)32-6-5-16(33)11-32;22-21(23,24)32-17-3-1-15(2-4-17)28-20(31)13-7-18(14-8-25-12-26-9-14)19(27-10-13)29-6-5-16(30)11-29;21-33(22,23,24,25)17-3-1-15(2-4-17)29-20(32)13-7-18(14-8-26-12-27-9-14)19(28-10-13)30-6-5-16(31)11-30/h4-7,10-13,15,19,30H,8-9,14H2,1-3H3,(H,28,31);3-6,9-11,15,32H,7-8,12H2,1-2H3,(H,29,33);1-4,7-10,12,17,33H,5-6,11H2,(H,31,34);1-4,7-10,12,16,33H,5-6,11H2,(H,31,34);1-4,7-10,12,16,30H,5-6,11H2,(H,28,31);1-4,7-10,12,16,31H,5-6,11H2,(H,29,32)/t19-;15-;17-;3*16-/m111111/s1
• InChIKey: OFSNCMWGDRXQBY-GIZMHHQJSA-N
• XLogP: 24.53
• TPSA: 593.59 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 42
• Rotatable Bonds: 36
• Heavy Atoms: 202
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2912.07
LogP ≤ 5	24.53
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	42

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'alkyl_halide', 'substructure': 'N/A'}, {'alert_name': 'Perfluorinated_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide?

The IUPAC name of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide (CID 159980675) is N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide.

What is the SMILES notation for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide?

The canonical SMILES for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide is CC(C)(C)Oc1ccc(NC(=O)c2cnc(N3CC[C@@H](O)C3)c(-c3cncnc3)c2)cc1.COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CC[C@@H](O)C2)c(OC)n1.O=C(Nc1ccc(C(F)(F)C(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(OC(F)(F)C(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(S(F)(F)(F)(F)F)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.O=C(Nc1ccc(SC(F)(F)Cl)cc1)c1cnc(N2CC[C@@H](O)C2)c(-c2cncnc2)c1.

What is the InChIKey of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide?

The InChIKey is OFSNCMWGDRXQBY-GIZMHHQJSA-N. The full InChI is InChI=1S/C24H27N5O3.C23H22ClF2N5O5.C22H18ClF4N5O2.C22H18F5N5O3.C21H18ClF2N5O2S.C20H18F5N5O2S/c1-24(2,3)32-20-6-4-18(5-7-20)28-23(31)16-10-21(17-11-25-15-26-12-17)22(27-13-16)29-9-8-19(30)14-29;1-34-21-18(11-28-22(30-21)35-2)17-9-13(10-27-19(17)31-8-7-15(32)12-31)20(33)29-14-3-5-16(6-4-14)36-23(24,25)26;23-22(26,27)21(24,25)15-1-3-16(4-2-15)31-20(34)13-7-18(14-8-28-12-29-9-14)19(30-10-13)32-6-5-17(33)11-32;23-21(24,25)22(26,27)35-17-3-1-15(2-4-17)31-20(34)13-7-18(14-8-28-12-29-9-14)19(30-10-13)32-6-5-16(33)11-32;22-21(23,24)32-17-3-1-15(2-4-17)28-20(31)13-7-18(14-8-25-12-26-9-14)19(27-10-13)29-6-5-16(30)11-29;21-33(22,23,24,25)17-3-1-15(2-4-17)29-20(32)13-7-18(14-8-26-12-27-9-14)19(28-10-13)30-6-5-16(31)11-30/h4-7,10-13,15,19,30H,8-9,14H2,1-3H3,(H,28,31);3-6,9-11,15,32H,7-8,12H2,1-2H3,(H,29,33);1-4,7-10,12,17,33H,5-6,11H2,(H,31,34);1-4,7-10,12,16,33H,5-6,11H2,(H,31,34);1-4,7-10,12,16,30H,5-6,11H2,(H,28,31);1-4,7-10,12,16,31H,5-6,11H2,(H,29,32)/t19-;15-;17-;3*16-/m111111/s1.

What are the key properties of N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide?

N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide has a molecular weight of 2912.07 g/mol, XLogP of 24.53, 36 rotatable bonds, 12 hydrogen bond donors, and 42 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[chloro(difluoro)methoxy]phenyl]-5-(2,4-dimethoxypyrimidin-5-yl)-6-[(3R)-3-hydroxypyrrolidin-1-yl]pyridine-3-carboxamide;N-[4-[chloro(difluoro)methyl]sulfanylphenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;N-[4-(2-chloro-1,1,2,2-tetrafluoroethyl)phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-[(2-methylpropan-2-yl)oxy]phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(1,1,2,2,2-pentafluoroethoxy)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide;6-[(3R)-3-hydroxypyrrolidin-1-yl]-N-[4-(pentafluoro-λ6-sulfanyl)phenyl]-5-pyrimidin-5-ylpyridine-3-carboxamide is sourced from PubChem (CID 159980675), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).