6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide

C116H115ClN32O10 — CID 159997255

IUPAC6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
SMILESCOc1ccc2c(c1)CN(c1cccc(C(=O)Nc3cnccc3N3CCNCC3)n1)C2.COc1cccc2c1CN(c1cccc(C(=O)Nc3cc(N4CCNCC4)ccn3)n1)C2=O.Cn1c(=O)n(-c2cccc(C(=O)Nc3cnccc3N3CCNCC3)n2)c2ccccc21.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2nc3ccccc3[nH]2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(N2Cc3cc(Cl)ccc3C2=O)n1
InChIInChI=1S/C24H24N6O3.C24H26N6O2.C23H21ClN6O2.C23H23N7O2.C22H21N7O/c1-33-20-6-2-4-17-18(20)15-30(24(17)32)22-7-3-5-19(27-22)23(31)28-21-14-16(8-9-26-21)29-12-10-25-11-13-29;1-32-19-6-5-17-15-30(16-18(17)13-19)23-4-2-3-20(27-23)24(31)28-21-14-26-8-7-22(21)29-11-9-25-10-12-29;24-16-4-5-17-15(12-16)14-30(23(17)32)21-3-1-2-18(27-21)22(31)28-19-13-26-7-6-20(19)29-10-8-25-9-11-29;1-28-19-6-2-3-7-20(19)30(23(28)32)21-8-4-5-16(26-21)22(31)27-17-15-25-10-9-18(17)29-13-11-24-12-14-29;30-22(28-19-14-24-9-8-20(19)29-12-10-23-11-13-29)18-7-3-6-17(25-18)21-26-15-4-1-2-5-16(15)27-21/h2-9,14,25H,10-13,15H2,1H3,(H,26,28,31);2-8,13-14,25H,9-12,15-16H2,1H3,(H,28,31);1-7,12-13,25H,8-11,14H2,(H,28,31);2-10,15,24H,11-14H2,1H3,(H,27,31);1-9,14,23H,10-13H2,(H,26,27)(H,28,30)
InChIKeyOHRSZAAFSQZJBB-UHFFFAOYSA-N
MW2152.86 g/mol
LogP12.39
Rot. Bonds22

About 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide

6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide (PubChem CID 159997255) has the molecular formula C116H115ClN32O10 and a molecular weight of 2152.86 g/mol. Its IUPAC name is 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide.

Molecular Properties

Compound Name6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
PubChem CID159997255
Molecular FormulaC116H115ClN32O10
Molecular Weight2152.86 g/mol
Exact Mass2150.92
IUPAC Name6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
SMILESCOc1ccc2c(c1)CN(c1cccc(C(=O)Nc3cnccc3N3CCNCC3)n1)C2.COc1cccc2c1CN(c1cccc(C(=O)Nc3cc(N4CCNCC4)ccn3)n1)C2=O.Cn1c(=O)n(-c2cccc(C(=O)Nc3cnccc3N3CCNCC3)n2)c2ccccc21.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2nc3ccccc3[nH]2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(N2Cc3cc(Cl)ccc3C2=O)n1
InChIInChI=1S/C24H24N6O3.C24H26N6O2.C23H21ClN6O2.C23H23N7O2.C22H21N7O/c1-33-20-6-2-4-17-18(20)15-30(24(17)32)22-7-3-5-19(27-22)23(31)28-21-14-16(8-9-26-21)29-12-10-25-11-13-29;1-32-19-6-5-17-15-30(16-18(17)13-19)23-4-2-3-20(27-23)24(31)28-21-14-26-8-7-22(21)29-11-9-25-10-12-29;24-16-4-5-17-15(12-16)14-30(23(17)32)21-3-1-2-18(27-21)22(31)28-19-13-26-7-6-20(19)29-10-8-25-9-11-29;1-28-19-6-2-3-7-20(19)30(23(28)32)21-8-4-5-16(26-21)22(31)27-17-15-25-10-9-18(17)29-13-11-24-12-14-29;30-22(28-19-14-24-9-8-20(19)29-12-10-23-11-13-29)18-7-3-6-17(25-18)21-26-15-4-1-2-5-16(15)27-21/h2-9,14,25H,10-13,15H2,1H3,(H,26,28,31);2-8,13-14,25H,9-12,15-16H2,1H3,(H,28,31);1-7,12-13,25H,8-11,14H2,(H,28,31);2-10,15,24H,11-14H2,1H3,(H,27,31);1-9,14,23H,10-13H2,(H,26,27)(H,28,30)
InChIKeyOHRSZAAFSQZJBB-UHFFFAOYSA-N
XLogP12.39
TPSA468.68 Ų
H-Bond Donors11
H-Bond Acceptors34
Rotatable Bonds22
Heavy Atoms159
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002152.86
LogP ≤ 512.39
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1034

Analyze 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

6-(7-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;methyl 3-oxo-2-[6-[(4-piperazin-1-yl-3-pyridinyl)carbamoyl]-2-pyridinyl]-1H-isoindole-5-carboxylate;6-[6-(2-morpholin-4-ylethoxy)-3-oxo-1H-isoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-[3-(2-morpholin-4-ylethyl)-2-oxobenzimidazol-1-yl]-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
CID 158726315
6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
CID 25174250
2-(5-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyrimidine-4-carboxamide
CID 59569538
6-[(2-methoxyphenyl)carbamoylamino]-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
CID 25176017
N-(5-cyano-2-piperazin-1-ylphenyl)-2-(3-methyl-2-oxobenzimidazol-1-yl)-1,3-thiazole-4-carboxamide;N-[2-(1,4-diazepan-1-yl)-5-fluorophenyl]-2-(5-methoxy-3-oxo-1H-isoindol-2-yl)-1,3-thiazole-4-carboxamide;2-(3,3-dimethyl-2-oxoindol-1-yl)-N-(5-fluoro-2-piperazin-1-ylphenyl)-1,3-thiazole-4-carboxamide;2-(3,3-dimethyl-2-oxoindol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide;N-(5-fluoro-2-piperazin-1-ylphenyl)-2-(5-methoxy-3-oxo-1H-isoindol-2-yl)-1,3-thiazole-4-carboxamide
CID 159300528
6-(5,6-dimethoxy-3-oxo-1H-isoindol-2-yl)-N-(2-piperazin-1-ylphenyl)pyrazine-2-carboxamide
CID 59569238
6-(2-oxo-3-piperidin-4-ylbenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
CID 25175229
2-(7-methoxy-3-oxo-1,4-dihydroisoquinolin-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)-1,3-thiazole-4-carboxamide
CID 24952335
tert-butyl 4-[3-[(6-bromopyridine-2-carbonyl)amino]-4-pyridinyl]piperazine-1-carboxylate;tert-butyl 4-[3-[[6-(5-methoxy-3-oxo-1H-isoindol-2-yl)pyridine-2-carbonyl]amino]-4-pyridinyl]piperazine-1-carboxylate
CID 162085304
6-(1H-indol-5-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1H-indol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide
CID 143750719
1-(2,5-dimethoxyphenyl)-3-[6-[1-[(4-piperazin-1-yl-3-pyridinyl)amino]ethenyl]-2-pyridinyl]urea
CID 89210298
2-[5-methoxy-6-(2-methoxyethoxy)-1,3-dihydroisoindol-2-yl]-N-(4-piperazin-1-yl-3-pyridinyl)pyrimidine-4-carboxamide
CID 59569232

Frequently Asked Questions

What is the IUPAC name of 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide?
The IUPAC name of 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide (CID 159997255) is 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide.
What is the SMILES notation for 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide?
The canonical SMILES for 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide is COc1ccc2c(c1)CN(c1cccc(C(=O)Nc3cnccc3N3CCNCC3)n1)C2.COc1cccc2c1CN(c1cccc(C(=O)Nc3cc(N4CCNCC4)ccn3)n1)C2=O.Cn1c(=O)n(-c2cccc(C(=O)Nc3cnccc3N3CCNCC3)n2)c2ccccc21.O=C(Nc1cnccc1N1CCNCC1)c1cccc(-c2nc3ccccc3[nH]2)n1.O=C(Nc1cnccc1N1CCNCC1)c1cccc(N2Cc3cc(Cl)ccc3C2=O)n1.
What is the InChIKey of 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide?
The InChIKey is OHRSZAAFSQZJBB-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H24N6O3.C24H26N6O2.C23H21ClN6O2.C23H23N7O2.C22H21N7O/c1-33-20-6-2-4-17-18(20)15-30(24(17)32)22-7-3-5-19(27-22)23(31)28-21-14-16(8-9-26-21)29-12-10-25-11-13-29;1-32-19-6-5-17-15-30(16-18(17)13-19)23-4-2-3-20(27-23)24(31)28-21-14-26-8-7-22(21)29-11-9-25-10-12-29;24-16-4-5-17-15(12-16)14-30(23(17)32)21-3-1-2-18(27-21)22(31)28-19-13-26-7-6-20(19)29-10-8-25-9-11-29;1-28-19-6-2-3-7-20(19)30(23(28)32)21-8-4-5-16(26-21)22(31)27-17-15-25-10-9-18(17)29-13-11-24-12-14-29;30-22(28-19-14-24-9-8-20(19)29-12-10-23-11-13-29)18-7-3-6-17(25-18)21-26-15-4-1-2-5-16(15)27-21/h2-9,14,25H,10-13,15H2,1H3,(H,26,28,31);2-8,13-14,25H,9-12,15-16H2,1H3,(H,28,31);1-7,12-13,25H,8-11,14H2,(H,28,31);2-10,15,24H,11-14H2,1H3,(H,27,31);1-9,14,23H,10-13H2,(H,26,27)(H,28,30).
What are the key properties of 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide?
6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide has a molecular weight of 2152.86 g/mol, XLogP of 12.39, 22 rotatable bonds, 11 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for 6-(1H-benzimidazol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(6-chloro-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(5-methoxy-1,3-dihydroisoindol-2-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide;6-(7-methoxy-3-oxo-1H-isoindol-2-yl)-N-(4-piperazin-1-yl-2-pyridinyl)pyridine-2-carboxamide;6-(3-methyl-2-oxobenzimidazol-1-yl)-N-(4-piperazin-1-yl-3-pyridinyl)pyridine-2-carboxamide is sourced from PubChem (CID 159997255), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).