2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

C124H91Cl3F8N28 — CID 160026495

IUPAC2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
SMILESCN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=CC=CC=C5F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)C(F)(F)F)F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CC(=C(N=C3)N)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CN=CC(=C3)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F
InChIInChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5.C23H16FN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3;2-14H,1H3
InChIKeyOLHBZKCLXUVBNI-UHFFFAOYSA-N
MW2231.60 g/mol
LogP—
Rot. Bonds17

About 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine

2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (PubChem CID 160026495) has the molecular formula C124H91Cl3F8N28 and a molecular weight of 2231.60 g/mol. Its IUPAC name is 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.

Molecular Properties

Compound Name2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
PubChem CID160026495
Molecular FormulaC124H91Cl3F8N28
Molecular Weight2231.60 g/mol
Exact Mass2229.70
IUPAC Name2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
SMILESCN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=CC=CC=C5F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)C(F)(F)F)F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CC(=C(N=C3)N)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CN=CC(=C3)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F
InChIInChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5.C23H16FN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3;2-14H,1H3
InChIKeyOLHBZKCLXUVBNI-UHFFFAOYSA-N
XLogP—
TPSA333.00 Ų
H-Bond Donors3
H-Bond Acceptors31
Rotatable Bonds17
Heavy Atoms163
Complexity3210

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 5002231.60
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1031

Analyze 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The IUPAC name of 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine (CID 160026495) is 2-(5-chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine.
What is the SMILES notation for 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The canonical SMILES for 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=CC=CC=C5F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)C(F)(F)F)F.CN1C=C(C=N1)C2=CN=CC(=C2)C3=CC(=NC4=C3C=CC=N4)C5=C(C=CC(=C5)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CC(=C(N=C3)N)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F.C1CNCCC1N2C=C(C=N2)C3=CN=CC(=C3)C4=CC(=NC5=C4C=CC=N5)C6=C(C=CC(=C6)Cl)F.
What is the InChIKey of 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
The InChIKey is OLHBZKCLXUVBNI-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H23ClFN7.C27H22ClFN6.C24H15F4N5.C23H15ClFN5.C23H16FN5/c28-18-3-4-24(29)23(11-18)25-12-21(20-2-1-7-32-27(20)35-25)22-10-16(13-33-26(22)30)17-14-34-36(15-17)19-5-8-31-9-6-19;28-20-3-4-25(29)24(11-20)26-12-23(22-2-1-7-32-27(22)34-26)18-10-17(13-31-14-18)19-15-33-35(16-19)21-5-8-30-9-6-21;1-33-13-16(12-31-33)14-7-15(11-29-10-14)19-9-22(32-23-18(19)3-2-6-30-23)20-8-17(24(26,27)28)4-5-21(20)25;1-30-13-16(12-28-30)14-7-15(11-26-10-14)19-9-22(20-8-17(24)4-5-21(20)25)29-23-18(19)3-2-6-27-23;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h1-4,7,10-15,19,31H,5-6,8-9H2,(H2,30,33);1-4,7,10-16,21,30H,5-6,8-9H2;2-13H,1H3;2-13H,1H3;2-14H,1H3.
What are the key properties of 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine?
2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine has a molecular weight of 2231.60 g/mol, XLogP of not available, 17 rotatable bonds, 3 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(5-Chloro-2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;3-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine;2-(5-chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine is sourced from PubChem (CID 160026495), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).