(2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide

C140H130F12N38O8 — CID 160515103

About (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide

(2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide (PubChem CID 160515103) has the molecular formula C140H130F12N38O8 and a molecular weight of 2700.81 g/mol. Its IUPAC name is (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide.

Molecular Properties

• Compound Name: (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide
• PubChem CID: 160515103
• Molecular Formula: C140H130F12N38O8
• Molecular Weight: 2700.81 g/mol
• Exact Mass: 2699.07
• IUPAC Name: (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide
• SMILES: C[C@H]1CCC(=O)N1c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.Cc1[nH]ccc1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1.Cc1[nH]ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(F)(F)F)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)C3C[C@H]3c3ncccn3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3ncccn3)ncc2c(N)n1.Cc1cn(C)c(C)c1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1.Cc1cn(C)c(C)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(F)(F)F)ncc2c(N)n1
• InChI: InChI=1S/2C23H20N6O.2C20H20F3N5O.2C18H16F3N5O.C18H18N6O2/c2*1-13-5-2-3-6-15(13)19-9-14-10-20(27-12-18(14)21(24)28-19)29-23(30)17-11-16(17)22-25-7-4-8-26-22;2*1-9-8-28(3)10(2)17(9)15-4-11-5-16(25-7-13(11)18(24)26-15)27-19(29)12-6-14(12)20(21,22)23;2*1-8-10(2-3-23-8)14-4-9-5-15(24-7-12(9)16(22)25-14)26-17(27)11-6-13(11)18(19,20)21;1-9-2-3-16(25)24(9)15-6-10-5-14(21-8-13(10)17(20)23-15)22-18(26)12-4-11(12)7-19/h2*2-10,12,16-17H,11H2,1H3,(H2,24,28)(H,27,29,30);2*4-5,7-8,12,14H,6H2,1-3H3,(H2,24,26)(H,25,27,29);2*2-5,7,11,13,23H,6H2,1H3,(H2,22,25)(H,24,26,27);5-6,8-9,11-12H,2-4H2,1H3,(H2,20,23)(H,21,22,26)/t16-,17?;16-,17-;12-,14-;;11-,13-;;9-,11+,12-/m100.1.0/s1
• InChIKey: QTNXUYUKKGRLFH-VJBNUDDTSA-N
• XLogP: 24.51
• TPSA: 703.40 Ų
• H-Bond Donors: 16
• H-Bond Acceptors: 36
• Rotatable Bonds: 23
• Heavy Atoms: 198
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2700.81
LogP ≤ 5	24.51
H-Bond Donors ≤ 5	16
H-Bond Acceptors ≤ 10	36

Frequently Asked Questions

What is the IUPAC name of (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide?

The IUPAC name of (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide (CID 160515103) is (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide.

What is the SMILES notation for (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide?

The canonical SMILES for (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide is C[C@H]1CCC(=O)N1c1cc2cc(NC(=O)[C@H]3C[C@@H]3C#N)ncc2c(N)n1.Cc1[nH]ccc1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1.Cc1[nH]ccc1-c1cc2cc(NC(=O)[C@@H]3C[C@H]3C(F)(F)F)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)C3C[C@H]3c3ncccn3)ncc2c(N)n1.Cc1ccccc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3c3ncccn3)ncc2c(N)n1.Cc1cn(C)c(C)c1-c1cc2cc(NC(=O)C3CC3C(F)(F)F)ncc2c(N)n1.Cc1cn(C)c(C)c1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C(F)(F)F)ncc2c(N)n1.

What is the InChIKey of (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide?

The InChIKey is QTNXUYUKKGRLFH-VJBNUDDTSA-N. The full InChI is InChI=1S/2C23H20N6O.2C20H20F3N5O.2C18H16F3N5O.C18H18N6O2/c2*1-13-5-2-3-6-15(13)19-9-14-10-20(27-12-18(14)21(24)28-19)29-23(30)17-11-16(17)22-25-7-4-8-26-22;2*1-9-8-28(3)10(2)17(9)15-4-11-5-16(25-7-13(11)18(24)26-15)27-19(29)12-6-14(12)20(21,22)23;2*1-8-10(2-3-23-8)14-4-9-5-15(24-7-12(9)16(22)25-14)26-17(27)11-6-13(11)18(19,20)21;1-9-2-3-16(25)24(9)15-6-10-5-14(21-8-13(10)17(20)23-15)22-18(26)12-4-11(12)7-19/h2*2-10,12,16-17H,11H2,1H3,(H2,24,28)(H,27,29,30);2*4-5,7-8,12,14H,6H2,1-3H3,(H2,24,26)(H,25,27,29);2*2-5,7,11,13,23H,6H2,1H3,(H2,22,25)(H,24,26,27);5-6,8-9,11-12H,2-4H2,1H3,(H2,20,23)(H,21,22,26)/t16-,17?;16-,17-;12-,14-;;11-,13-;;9-,11+,12-/m100.1.0/s1.

What are the key properties of (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide?

(2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide has a molecular weight of 2700.81 g/mol, XLogP of 24.51, 23 rotatable bonds, 16 hydrogen bond donors, and 36 hydrogen bond acceptors.

Where does this data come from?

All data for (2R)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;cis-(1S,2S)-N-[8-amino-6-[(2S)-2-methyl-5-oxopyrrolidin-1-yl]-2,7-naphthyridin-3-yl]-2-cyanocyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(2-methylphenyl)-2,7-naphthyridin-3-yl]-2-pyrimidin-2-ylcyclopropane-1-carboxamide;trans-(1R,2R)-N-[8-amino-6-(2-methyl-1H-pyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide;trans-(1S,2S)-N-[8-amino-6-(1,2,4-trimethylpyrrol-3-yl)-2,7-naphthyridin-3-yl]-2-(trifluoromethyl)cyclopropane-1-carboxamide is sourced from PubChem (CID 160515103), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).