6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline

C130H118Cl3F5N22O6 — CID 160516324

About 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline

6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline (PubChem CID 160516324) has the molecular formula C130H118Cl3F5N22O6 and a molecular weight of 2285.87 g/mol. Its IUPAC name is 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline.

Molecular Properties

• Compound Name: 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline
• PubChem CID: 160516324
• Molecular Formula: C130H118Cl3F5N22O6
• Molecular Weight: 2285.87 g/mol
• Exact Mass: 2282.86
• IUPAC Name: 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline
• SMILES: CN(C)CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCN(C)CC4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCN4CCN(C)CC4)c3c2)ccc1F.Cc1ccc(Oc2ncnc3ccc(-c4cccnc4-c4ccc(F)c(Cl)c4)cc23)cn1.O=C1CCCN1CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12
• InChI: InChI=1S/C28H30FN5O.C27H28FN5O.C26H22ClFN4O2.C25H16ClFN4O.C24H22ClFN4O/c1-20-17-22(6-8-25(20)29)27-23(5-3-10-30-27)21-7-9-26-24(18-21)28(32-19-31-26)35-16-4-11-34-14-12-33(2)13-15-34;1-19-16-21(5-7-24(19)28)26-22(4-3-9-29-26)20-6-8-25-23(17-20)27(31-18-30-25)34-15-14-33-12-10-32(2)11-13-33;27-21-15-18(6-8-22(21)28)25-19(4-1-10-29-25)17-7-9-23-20(14-17)26(31-16-30-23)34-13-3-12-32-11-2-5-24(32)33;1-15-4-7-18(13-29-15)32-25-20-11-16(6-9-23(20)30-14-31-25)19-3-2-10-28-24(19)17-5-8-22(27)21(26)12-17;1-30(2)11-4-12-31-24-19-13-16(7-9-22(19)28-15-29-24)18-5-3-10-27-23(18)17-6-8-21(26)20(25)14-17/h3,5-10,17-19H,4,11-16H2,1-2H3;3-9,16-18H,10-15H2,1-2H3;1,4,6-10,14-16H,2-3,5,11-13H2;2-14H,1H3;3,5-10,13-15H,4,11-12H2,1-2H3
• InChIKey: QTRYRNRXCONPSF-UHFFFAOYSA-N
• XLogP: 26.93
• TPSA: 288.90 Ų
• H-Bond Acceptors: 27
• Rotatable Bonds: 31
• Heavy Atoms: 166
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2285.87
LogP ≤ 5	26.93
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	27

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline?

The IUPAC name of 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline (CID 160516324) is 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline.

What is the SMILES notation for 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline?

The canonical SMILES for 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline is CN(C)CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCCN4CCN(C)CC4)c3c2)ccc1F.Cc1cc(-c2ncccc2-c2ccc3ncnc(OCCN4CCN(C)CC4)c3c2)ccc1F.Cc1ccc(Oc2ncnc3ccc(-c4cccnc4-c4ccc(F)c(Cl)c4)cc23)cn1.O=C1CCCN1CCCOc1ncnc2ccc(-c3cccnc3-c3ccc(F)c(Cl)c3)cc12.

What is the InChIKey of 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline?

The InChIKey is QTRYRNRXCONPSF-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30FN5O.C27H28FN5O.C26H22ClFN4O2.C25H16ClFN4O.C24H22ClFN4O/c1-20-17-22(6-8-25(20)29)27-23(5-3-10-30-27)21-7-9-26-24(18-21)28(32-19-31-26)35-16-4-11-34-14-12-33(2)13-15-34;1-19-16-21(5-7-24(19)28)26-22(4-3-9-29-26)20-6-8-25-23(17-20)27(31-18-30-25)34-15-14-33-12-10-32(2)11-13-33;27-21-15-18(6-8-22(21)28)25-19(4-1-10-29-25)17-7-9-23-20(14-17)26(31-16-30-23)34-13-3-12-32-11-2-5-24(32)33;1-15-4-7-18(13-29-15)32-25-20-11-16(6-9-23(20)30-14-31-25)19-3-2-10-28-24(19)17-5-8-22(27)21(26)12-17;1-30(2)11-4-12-31-24-19-13-16(7-9-22(19)28-15-29-24)18-5-3-10-27-23(18)17-6-8-21(26)20(25)14-17/h3,5-10,17-19H,4,11-16H2,1-2H3;3-9,16-18H,10-15H2,1-2H3;1,4,6-10,14-16H,2-3,5,11-13H2;2-14H,1H3;3,5-10,13-15H,4,11-12H2,1-2H3.

What are the key properties of 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline?

6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline has a molecular weight of 2285.87 g/mol, XLogP of 26.93, 31 rotatable bonds, 0 hydrogen bond donors, and 27 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]-4-[(6-methyl-3-pyridinyl)oxy]quinazoline;3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxy-N,N-dimethylpropan-1-amine;1-[3-[6-[2-(3-chloro-4-fluorophenyl)-3-pyridinyl]quinazolin-4-yl]oxypropyl]pyrrolidin-2-one;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[2-(4-methylpiperazin-1-yl)ethoxy]quinazoline;6-[2-(4-fluoro-3-methylphenyl)-3-pyridinyl]-4-[3-(4-methylpiperazin-1-yl)propoxy]quinazoline is sourced from PubChem (CID 160516324), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).