N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide

C142H160N34O10S2 — CID 160518582

About N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide

N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide (PubChem CID 160518582) has the molecular formula C142H160N34O10S2 and a molecular weight of 2567.20 g/mol. Its IUPAC name is N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide.

Molecular Properties

• Compound Name: N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide
• PubChem CID: 160518582
• Molecular Formula: C142H160N34O10S2
• Molecular Weight: 2567.20 g/mol
• Exact Mass: 2565.25
• IUPAC Name: N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide
• SMILES: CC(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCN(CC5CC5)CC4)cc3)n2)cc1.CC(=O)Nc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)ncc2C)cc1.CCCCN1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CCCN1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CCS(=O)(=O)N1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CS(=O)(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1
• InChI: InChI=1S/C26H30N6O.C26H32N6O.C25H30N6O.C24H28N6O3S.C21H22N4O3S.C20H18N6O/c1-19(33)28-22-6-4-21(5-7-22)25-12-13-27-26(30-25)29-23-8-10-24(11-9-23)32-16-14-31(15-17-32)18-20-2-3-20;1-3-4-15-31-16-18-32(19-17-31)24-11-9-23(10-12-24)29-26-27-14-13-25(30-26)21-5-7-22(8-6-21)28-20(2)33;1-3-14-30-15-17-31(18-16-30)23-10-8-22(9-11-23)28-25-26-13-12-24(29-25)20-4-6-21(7-5-20)27-19(2)32;1-3-34(32,33)30-16-14-29(15-17-30)22-10-8-21(9-11-22)27-24-25-13-12-23(28-24)19-4-6-20(7-5-19)26-18(2)31;1-29(26,27)19-8-2-16(3-9-19)20-10-11-22-21(24-20)23-17-4-6-18(7-5-17)25-12-14-28-15-13-25;1-12-10-21-20(24-17-7-8-18-15(9-17)11-22-26-18)25-19(12)14-3-5-16(6-4-14)23-13(2)27/h4-13,20H,2-3,14-18H2,1H3,(H,28,33)(H,27,29,30);5-14H,3-4,15-19H2,1-2H3,(H,28,33)(H,27,29,30);4-13H,3,14-18H2,1-2H3,(H,27,32)(H,26,28,29);4-13H,3,14-17H2,1-2H3,(H,26,31)(H,25,27,28);2-11H,12-15H2,1H3,(H,22,23,24);3-11H,1-2H3,(H,22,26)(H,23,27)(H,21,24,25)
• InChIKey: QTZAWBIJIPFWOM-UHFFFAOYSA-N
• XLogP: 24.00
• TPSA: 507.71 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 37
• Rotatable Bonds: 38
• Heavy Atoms: 188
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2567.20
LogP ≤ 5	24.00
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	37

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'anil_di_alk_A(478)', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide?

The IUPAC name of N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide (CID 160518582) is N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide.

What is the SMILES notation for N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide?

The canonical SMILES for N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide is CC(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCN(CC5CC5)CC4)cc3)n2)cc1.CC(=O)Nc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)ncc2C)cc1.CCCCN1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CCCN1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CCS(=O)(=O)N1CCN(c2ccc(Nc3nccc(-c4ccc(NC(C)=O)cc4)n3)cc2)CC1.CS(=O)(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1.

What is the InChIKey of N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide?

The InChIKey is QTZAWBIJIPFWOM-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H30N6O.C26H32N6O.C25H30N6O.C24H28N6O3S.C21H22N4O3S.C20H18N6O/c1-19(33)28-22-6-4-21(5-7-22)25-12-13-27-26(30-25)29-23-8-10-24(11-9-23)32-16-14-31(15-17-32)18-20-2-3-20;1-3-4-15-31-16-18-32(19-17-31)24-11-9-23(10-12-24)29-26-27-14-13-25(30-26)21-5-7-22(8-6-21)28-20(2)33;1-3-14-30-15-17-31(18-16-30)23-10-8-22(9-11-23)28-25-26-13-12-24(29-25)20-4-6-21(7-5-20)27-19(2)32;1-3-34(32,33)30-16-14-29(15-17-30)22-10-8-21(9-11-22)27-24-25-13-12-23(28-24)19-4-6-20(7-5-19)26-18(2)31;1-29(26,27)19-8-2-16(3-9-19)20-10-11-22-21(24-20)23-17-4-6-18(7-5-17)25-12-14-28-15-13-25;1-12-10-21-20(24-17-7-8-18-15(9-17)11-22-26-18)25-19(12)14-3-5-16(6-4-14)23-13(2)27/h4-13,20H,2-3,14-18H2,1H3,(H,28,33)(H,27,29,30);5-14H,3-4,15-19H2,1-2H3,(H,28,33)(H,27,29,30);4-13H,3,14-18H2,1-2H3,(H,27,32)(H,26,28,29);4-13H,3,14-17H2,1-2H3,(H,26,31)(H,25,27,28);2-11H,12-15H2,1H3,(H,22,23,24);3-11H,1-2H3,(H,22,26)(H,23,27)(H,21,24,25).

What are the key properties of N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide?

N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide has a molecular weight of 2567.20 g/mol, XLogP of 24.00, 38 rotatable bonds, 12 hydrogen bond donors, and 37 hydrogen bond acceptors.

Where does this data come from?

All data for N-[4-[2-[4-(4-butylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-[4-(cyclopropylmethyl)piperazin-1-yl]anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide;N-[4-[2-(1H-indazol-5-ylamino)-5-methylpyrimidin-4-yl]phenyl]acetamide;4-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine;N-[4-[2-[4-(4-propylpiperazin-1-yl)anilino]pyrimidin-4-yl]phenyl]acetamide is sourced from PubChem (CID 160518582), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).