2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol

C224H273N33O12 — CID 160563323

IUPAC2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol
SMILESCO[C@@H]1CCN(c2ccc3nc(C4CC4)nc(N4CCC(c5ccccc5C)CC4)c3c2)C1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(N(C)C)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)CC4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@@H](O)C4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@H](O)C4)cc23)CC1
InChIInChI=1S/C30H39N5O.C29H36N4O2.2C28H34N4O2.C28H34N4O.C27H32N4O2.2C27H32N4O/c1-33(2)23-14-18-34(19-15-23)24-10-11-27-26(20-24)30(32-29(31-27)22-8-9-22)35-16-12-21(13-17-35)25-6-4-5-7-28(25)36-3;1-34-23-13-17-32(18-14-23)22-9-10-26-25(19-22)29(31-28(30-26)21-7-8-21)33-15-11-20(12-16-33)24-5-3-4-6-27(24)35-2;1-33-22-13-16-32(18-22)21-9-10-25-24(17-21)28(30-27(29-25)20-7-8-20)31-14-11-19(12-15-31)23-5-3-4-6-26(23)34-2;1-34-26-5-3-2-4-23(26)19-10-14-32(15-11-19)28-24-18-21(31-16-12-22(33)13-17-31)8-9-25(24)29-27(30-28)20-6-7-20;1-19-5-3-4-6-24(19)20-11-14-31(15-12-20)28-25-17-22(32-16-13-23(18-32)33-2)9-10-26(25)29-27(30-28)21-7-8-21;1-33-25-5-3-2-4-22(25)18-10-13-30(14-11-18)27-23-16-20(31-15-12-21(32)17-31)8-9-24(23)28-26(29-27)19-6-7-19;2*1-18-4-2-3-5-23(18)19-10-13-30(14-11-19)27-24-16-21(31-15-12-22(32)17-31)8-9-25(24)28-26(29-27)20-6-7-20/h4-7,10-11,20-23H,8-9,12-19H2,1-3H3;3-6,9-10,19-21,23H,7-8,11-18H2,1-2H3;3-6,9-10,17,19-20,22H,7-8,11-16,18H2,1-2H3;2-5,8-9,18-20,22,33H,6-7,10-17H2,1H3;3-6,9-10,17,20-21,23H,7-8,11-16,18H2,1-2H3;2-5,8-9,16,18-19,21,32H,6-7,10-15,17H2,1H3;2*2-5,8-9,16,19-20,22,32H,6-7,10-15,17H2,1H3/t;;;;23-;;2*22-/m....1.10/s1
InChIKeyQZPHYXPRASVIPZ-KGUPKFSDSA-N
MW3619.87 g/mol
LogP40.37
Rot. Bonds41

About 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol

2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol (PubChem CID 160563323) has the molecular formula C224H273N33O12 and a molecular weight of 3619.87 g/mol. Its IUPAC name is 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol.

Molecular Properties

Compound Name2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol
PubChem CID160563323
Molecular FormulaC224H273N33O12
Molecular Weight3619.87 g/mol
Exact Mass3617.18
IUPAC Name2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol
SMILESCO[C@@H]1CCN(c2ccc3nc(C4CC4)nc(N4CCC(c5ccccc5C)CC4)c3c2)C1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(N(C)C)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)CC4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@@H](O)C4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@H](O)C4)cc23)CC1
InChIInChI=1S/C30H39N5O.C29H36N4O2.2C28H34N4O2.C28H34N4O.C27H32N4O2.2C27H32N4O/c1-33(2)23-14-18-34(19-15-23)24-10-11-27-26(20-24)30(32-29(31-27)22-8-9-22)35-16-12-21(13-17-35)25-6-4-5-7-28(25)36-3;1-34-23-13-17-32(18-14-23)22-9-10-26-25(19-22)29(31-28(30-26)21-7-8-21)33-15-11-20(12-16-33)24-5-3-4-6-27(24)35-2;1-33-22-13-16-32(18-22)21-9-10-25-24(17-21)28(30-27(29-25)20-7-8-20)31-14-11-19(12-15-31)23-5-3-4-6-26(23)34-2;1-34-26-5-3-2-4-23(26)19-10-14-32(15-11-19)28-24-18-21(31-16-12-22(33)13-17-31)8-9-25(24)29-27(30-28)20-6-7-20;1-19-5-3-4-6-24(19)20-11-14-31(15-12-20)28-25-17-22(32-16-13-23(18-32)33-2)9-10-26(25)29-27(30-28)21-7-8-21;1-33-25-5-3-2-4-22(25)18-10-13-30(14-11-18)27-23-16-20(31-15-12-21(32)17-31)8-9-24(23)28-26(29-27)19-6-7-19;2*1-18-4-2-3-5-23(18)19-10-13-30(14-11-19)27-24-16-21(31-15-12-22(32)17-31)8-9-25(24)28-26(29-27)20-6-7-20/h4-7,10-11,20-23H,8-9,12-19H2,1-3H3;3-6,9-10,19-21,23H,7-8,11-18H2,1-2H3;3-6,9-10,17,19-20,22H,7-8,11-16,18H2,1-2H3;2-5,8-9,18-20,22,33H,6-7,10-17H2,1H3;3-6,9-10,17,20-21,23H,7-8,11-16,18H2,1-2H3;2-5,8-9,16,18-19,21,32H,6-7,10-15,17H2,1H3;2*2-5,8-9,16,19-20,22,32H,6-7,10-15,17H2,1H3/t;;;;23-;;2*22-/m....1.10/s1
InChIKeyQZPHYXPRASVIPZ-KGUPKFSDSA-N
XLogP40.37
TPSA416.08 Ų
H-Bond Donors4
H-Bond Acceptors45
Rotatable Bonds41
Heavy Atoms269
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003619.87
LogP ≤ 540.37
H-Bond Donors ≤ 54
H-Bond Acceptors ≤ 1045

Analyze 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol with MolForge

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Related Compounds

US10118902, Example 175
CID 118617787
US10118902, Example 173
CID 118617781
US10118902, Example 79
CID 118610254
2-[[4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-2-(1-methylcyclopentyl)quinazolin-6-yl]-methylamino]ethanol;4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-N-methyl-2-(1-methylcyclopentyl)-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopentyl]quinazolin-6-amine;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopentyl]quinazolin-6-yl]-methylamino]ethanol
CID 157236988
2-(1-fluorocyclopropyl)-N-[2-(2-fluoroethoxy)ethyl]-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methylquinazolin-6-amine;2-[[2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-methylamino]ethanol;2-fluoroethyl trifluoromethanesulfonate
CID 158783998
CID 159950778
CID 159950778
4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine;2-[[4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-(1-methylcyclopentyl)quinazolin-6-yl]-methylamino]ethanol;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-2-(1-methylcyclopentyl)-N-(2-morpholin-4-ylethyl)quinazolin-6-amine
CID 160379175
2-cyclobutyl-N-(2-methoxyethyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methylquinazolin-6-amine;2-cyclobutyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;2-cyclobutyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-propylquinazolin-6-amine;4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine;2-[[4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-(1-methylcyclopentyl)quinazolin-6-yl]-methylamino]ethanol;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol
CID 160477296
2-[[4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-2-(1-methylcyclopentyl)quinazolin-6-yl]-methylamino]ethanol;4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-N-methyl-2-(1-methylcyclopentyl)-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-2-(1-methylcyclopentyl)-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopentyl]quinazolin-6-yl]-methylamino]ethanol
CID 160898927
4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine;2-[[4-[4-[2-(dimethylamino)phenyl]piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-(1-methylcyclopentyl)quinazolin-6-yl]-methylamino]ethanol;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine
CID 161385602
2-butan-2-yl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;2-butan-2-yl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-propylquinazolin-6-amine;4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-amine;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol
CID 161780425
2-butan-2-yl-N-(2-methoxyethyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methylquinazolin-6-amine;2-butan-2-yl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-(2-morpholin-4-ylethyl)quinazolin-6-amine;2-butan-2-yl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-N-methyl-N-propylquinazolin-6-amine;2-[[4-[4-(2-methoxyphenyl)piperidin-1-yl]-2-[1-(trifluoromethyl)cyclopropyl]quinazolin-6-yl]-methylamino]ethanol
CID 162064640

Frequently Asked Questions

What is the IUPAC name of 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol?
The IUPAC name of 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol (CID 160563323) is 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol.
What is the SMILES notation for 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol?
The canonical SMILES for 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol is CO[C@@H]1CCN(c2ccc3nc(C4CC4)nc(N4CCC(c5ccccc5C)CC4)c3c2)C1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(N(C)C)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(O)CC4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)C4)cc23)CC1.COc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CCC(OC)CC4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@@H](O)C4)cc23)CC1.Cc1ccccc1C1CCN(c2nc(C3CC3)nc3ccc(N4CC[C@H](O)C4)cc23)CC1.
What is the InChIKey of 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol?
The InChIKey is QZPHYXPRASVIPZ-KGUPKFSDSA-N. The full InChI is InChI=1S/C30H39N5O.C29H36N4O2.2C28H34N4O2.C28H34N4O.C27H32N4O2.2C27H32N4O/c1-33(2)23-14-18-34(19-15-23)24-10-11-27-26(20-24)30(32-29(31-27)22-8-9-22)35-16-12-21(13-17-35)25-6-4-5-7-28(25)36-3;1-34-23-13-17-32(18-14-23)22-9-10-26-25(19-22)29(31-28(30-26)21-7-8-21)33-15-11-20(12-16-33)24-5-3-4-6-27(24)35-2;1-33-22-13-16-32(18-22)21-9-10-25-24(17-21)28(30-27(29-25)20-7-8-20)31-14-11-19(12-15-31)23-5-3-4-6-26(23)34-2;1-34-26-5-3-2-4-23(26)19-10-14-32(15-11-19)28-24-18-21(31-16-12-22(33)13-17-31)8-9-25(24)29-27(30-28)20-6-7-20;1-19-5-3-4-6-24(19)20-11-14-31(15-12-20)28-25-17-22(32-16-13-23(18-32)33-2)9-10-26(25)29-27(30-28)21-7-8-21;1-33-25-5-3-2-4-22(25)18-10-13-30(14-11-18)27-23-16-20(31-15-12-21(32)17-31)8-9-24(23)28-26(29-27)19-6-7-19;2*1-18-4-2-3-5-23(18)19-10-13-30(14-11-19)27-24-16-21(31-15-12-22(32)17-31)8-9-25(24)28-26(29-27)20-6-7-20/h4-7,10-11,20-23H,8-9,12-19H2,1-3H3;3-6,9-10,19-21,23H,7-8,11-18H2,1-2H3;3-6,9-10,17,19-20,22H,7-8,11-16,18H2,1-2H3;2-5,8-9,18-20,22,33H,6-7,10-17H2,1H3;3-6,9-10,17,20-21,23H,7-8,11-16,18H2,1-2H3;2-5,8-9,16,18-19,21,32H,6-7,10-15,17H2,1H3;2*2-5,8-9,16,19-20,22,32H,6-7,10-15,17H2,1H3/t;;;;23-;;2*22-/m....1.10/s1.
What are the key properties of 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol?
2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol has a molecular weight of 3619.87 g/mol, XLogP of 40.37, 41 rotatable bonds, 4 hydrogen bond donors, and 45 hydrogen bond acceptors.
Where does this data come from?
All data for 2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(4-methoxypiperidin-1-yl)quinazoline;2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]-6-(3-methoxypyrrolidin-1-yl)quinazoline;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]-N,N-dimethylpiperidin-4-amine;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]piperidin-4-ol;1-[2-cyclopropyl-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;2-cyclopropyl-6-[(3R)-3-methoxypyrrolidin-1-yl]-4-[4-(2-methylphenyl)piperidin-1-yl]quinazoline;(3R)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol;(3S)-1-[2-cyclopropyl-4-[4-(2-methylphenyl)piperidin-1-yl]quinazolin-6-yl]pyrrolidin-3-ol is sourced from PubChem (CID 160563323), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).