2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine

C108H86ClF10N23 — CID 160598509

IUPAC2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
SMILESCn1cc(-c2cncc(-c3cc(-c4ccccc4F)nc4ncccc34)c2)cn1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1
InChIInChI=1S/C29H24F4N6.C28H24ClFN6.C28H22F4N6.C23H16FN5/c30-26-6-5-22(29(31,32)33)13-25(26)27-14-24(23-4-3-7-35-28(23)37-27)20-12-19(15-34-16-20)21-17-36-39(18-21)11-10-38-8-1-2-9-38;29-22-5-6-26(30)25(13-22)27-14-24(23-4-3-7-32-28(23)34-27)20-12-19(15-31-16-20)21-17-33-36(18-21)11-10-35-8-1-2-9-35;29-25-4-3-20(28(30,31)32)11-24(25)26-12-23(22-2-1-7-35-27(22)37-26)18-10-17(13-34-14-18)19-15-36-38(16-19)21-5-8-33-9-6-21;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h3-7,12-18H,1-2,8-11H2;3-7,12-18H,1-2,8-11H2;1-4,7,10-16,21,33H,5-6,8-9H2;2-14H,1H3
InChIKeyRDYOAYZUNSZHNA-UHFFFAOYSA-N
MW1931.47 g/mol
LogP23.79
Rot. Bonds19

About 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine

2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine (PubChem CID 160598509) has the molecular formula C108H86ClF10N23 and a molecular weight of 1931.47 g/mol. Its IUPAC name is 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine.

Molecular Properties

Compound Name2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
PubChem CID160598509
Molecular FormulaC108H86ClF10N23
Molecular Weight1931.47 g/mol
Exact Mass1929.70
IUPAC Name2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
SMILESCn1cc(-c2cncc(-c3cc(-c4ccccc4F)nc4ncccc34)c2)cn1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1
InChIInChI=1S/C29H24F4N6.C28H24ClFN6.C28H22F4N6.C23H16FN5/c30-26-6-5-22(29(31,32)33)13-25(26)27-14-24(23-4-3-7-35-28(23)37-27)20-12-19(15-34-16-20)21-17-36-39(18-21)11-10-38-8-1-2-9-38;29-22-5-6-26(30)25(13-22)27-14-24(23-4-3-7-32-28(23)34-27)20-12-19(15-31-16-20)21-17-33-36(18-21)11-10-35-8-1-2-9-35;29-25-4-3-20(28(30,31)32)11-24(25)26-12-23(22-2-1-7-35-27(22)37-26)18-10-17(13-34-14-18)19-15-36-38(16-19)21-5-8-33-9-6-21;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h3-7,12-18H,1-2,8-11H2;3-7,12-18H,1-2,8-11H2;1-4,7,10-16,21,33H,5-6,8-9H2;2-14H,1H3
InChIKeyRDYOAYZUNSZHNA-UHFFFAOYSA-N
XLogP23.79
TPSA244.47 Ų
H-Bond Donors1
H-Bond Acceptors23
Rotatable Bonds19
Heavy Atoms142
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001931.47
LogP ≤ 523.79
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 1023

Analyze 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine with MolForge

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Related Compounds

2-(5-Chloro-2-fluorophenyl)-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine
CID 53328062
3-[2-(5-Chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine
CID 53344957
2-(5-Chloro-2-fluoro-phenyl)-4-{5-[1-(2-pyrrolidin-1-yl-ethyl)-1H-pyrazol-4-yl]-pyridin-3-yl}-[1,8]naphthyridine
CID 53344959
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345068
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-ethylpiperidin-4-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345406
2-(5-Chloro-2-fluorophenyl)-4-[6-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-yl]-1,8-naphthyridine
CID 53345518
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(1-methylpyrrolidin-3-yl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345626
2-(5-chloro-2-fluorophenyl)-4-[5-[1-[(3S)-1-methylpyrrolidin-3-yl]pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345723
2-(5-chloro-2-fluorophenyl)-4-[5-[1-[(3R)-1-methylpyrrolidin-3-yl]pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 53345724
2-(5-Chloro-2-fluorophenyl)-4-[5-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine
CID 68264549
5-[2-(5-Chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]pyridin-2-amine
CID 68264729
2-[4-[5-[2-(5-chloro-2-fluorophenyl)-1,8-naphthyridin-4-yl]-3-pyridinyl]pyrazol-1-yl]-N-methylethanamine
CID 68264973

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine?
The IUPAC name of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine (CID 160598509) is 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine.
What is the SMILES notation for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine?
The canonical SMILES for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine is Cn1cc(-c2cncc(-c3cc(-c4ccccc4F)nc4ncccc34)c2)cn1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(C4CCNCC4)c3)c2)c2cccnc2n1.Fc1ccc(C(F)(F)F)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1.Fc1ccc(Cl)cc1-c1cc(-c2cncc(-c3cnn(CCN4CCCC4)c3)c2)c2cccnc2n1.
What is the InChIKey of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine?
The InChIKey is RDYOAYZUNSZHNA-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H24F4N6.C28H24ClFN6.C28H22F4N6.C23H16FN5/c30-26-6-5-22(29(31,32)33)13-25(26)27-14-24(23-4-3-7-35-28(23)37-27)20-12-19(15-34-16-20)21-17-36-39(18-21)11-10-38-8-1-2-9-38;29-22-5-6-26(30)25(13-22)27-14-24(23-4-3-7-32-28(23)34-27)20-12-19(15-31-16-20)21-17-33-36(18-21)11-10-35-8-1-2-9-35;29-25-4-3-20(28(30,31)32)11-24(25)26-12-23(22-2-1-7-35-27(22)37-26)18-10-17(13-34-14-18)19-15-36-38(16-19)21-5-8-33-9-6-21;1-29-14-17(13-27-29)15-9-16(12-25-11-15)20-10-22(19-5-2-3-7-21(19)24)28-23-18(20)6-4-8-26-23/h3-7,12-18H,1-2,8-11H2;3-7,12-18H,1-2,8-11H2;1-4,7,10-16,21,33H,5-6,8-9H2;2-14H,1H3.
What are the key properties of 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine?
2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine has a molecular weight of 1931.47 g/mol, XLogP of 23.79, 19 rotatable bonds, 1 hydrogen bond donors, and 23 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(5-chloro-2-fluorophenyl)-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine;2-(2-fluorophenyl)-4-[5-(1-methylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-(1-piperidin-4-ylpyrazol-4-yl)-3-pyridinyl]-1,8-naphthyridine;2-[2-fluoro-5-(trifluoromethyl)phenyl]-4-[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]-3-pyridinyl]-1,8-naphthyridine is sourced from PubChem (CID 160598509), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).