3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide

C159H166F17N21O19 — CID 160613806

IUPAC3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide
SMILESCCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc1C(F)(F)F.CNCc1cc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc(C(F)(F)F)c1.Cc1ccc(C(=O)Cc2ccc(CN)c(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CN)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CO)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1
InChIInChI=1S/C28H30F3N3O3.C27H29F3N4O3.C27H28F3N3O3.C26H27F3N4O3.C26H26F3N3O4.C25H26F2N4O3/c1-4-5-19-7-8-20(14-24(19)28(29,30)31)26(35)32-22-9-6-18(2)23(16-22)21-15-25(27(36)33(3)17-21)34-10-12-37-13-11-34;1-17-4-5-22(32-25(35)19-10-18(15-31-2)11-21(12-19)27(28,29)30)14-23(17)20-13-24(26(36)33(3)16-20)34-6-8-37-9-7-34;1-17-3-5-19(25(34)12-18-4-6-20(15-31)23(11-18)27(28,29)30)13-22(17)21-14-24(26(35)32(2)16-21)33-7-9-36-10-8-33;1-16-3-4-21(31-24(34)18-9-17(14-30)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)32(2)15-19)33-5-7-36-8-6-33;1-16-3-4-21(30-24(34)18-9-17(15-33)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)31(2)14-19)32-5-7-36-8-6-32;1-16-4-5-19(29-24(33)17-6-7-28-21(12-17)25(2,26)27)15-20(16)18-13-22(30(3)23(32)14-18)31-8-10-34-11-9-31/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,32,35);4-5,10-14,16,31H,6-9,15H2,1-3H3,(H,32,35);3-6,11,13-14,16H,7-10,12,15,31H2,1-2H3;3-4,9-13,15H,5-8,14,30H2,1-2H3,(H,31,34);3-4,9-14,33H,5-8,15H2,1-2H3,(H,30,34);4-7,12-15H,8-11H2,1-3H3,(H,29,33)
InChIKeyRFVAQZWYINCCCI-UHFFFAOYSA-N
MW2998.17 g/mol
LogP25.55
Rot. Bonds33

About 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide

3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide (PubChem CID 160613806) has the molecular formula C159H166F17N21O19 and a molecular weight of 2998.17 g/mol. Its IUPAC name is 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide.

Molecular Properties

Compound Name3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide
PubChem CID160613806
Molecular FormulaC159H166F17N21O19
Molecular Weight2998.17 g/mol
Exact Mass2996.24
IUPAC Name3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide
SMILESCCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc1C(F)(F)F.CNCc1cc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc(C(F)(F)F)c1.Cc1ccc(C(=O)Cc2ccc(CN)c(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CN)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CO)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1
InChIInChI=1S/C28H30F3N3O3.C27H29F3N4O3.C27H28F3N3O3.C26H27F3N4O3.C26H26F3N3O4.C25H26F2N4O3/c1-4-5-19-7-8-20(14-24(19)28(29,30)31)26(35)32-22-9-6-18(2)23(16-22)21-15-25(27(36)33(3)17-21)34-10-12-37-13-11-34;1-17-4-5-22(32-25(35)19-10-18(15-31-2)11-21(12-19)27(28,29)30)14-23(17)20-13-24(26(36)33(3)16-20)34-6-8-37-9-7-34;1-17-3-5-19(25(34)12-18-4-6-20(15-31)23(11-18)27(28,29)30)13-22(17)21-14-24(26(35)32(2)16-21)33-7-9-36-10-8-33;1-16-3-4-21(31-24(34)18-9-17(14-30)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)32(2)15-19)33-5-7-36-8-6-33;1-16-3-4-21(30-24(34)18-9-17(15-33)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)31(2)14-19)32-5-7-36-8-6-32;1-16-4-5-19(29-24(33)17-6-7-28-21(12-17)25(2,26)27)15-20(16)18-13-22(30(3)23(32)14-18)31-8-10-34-11-9-31/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,32,35);4-5,10-14,16,31H,6-9,15H2,1-3H3,(H,32,35);3-6,11,13-14,16H,7-10,12,15,31H2,1-2H3;3-4,9-13,15H,5-8,14,30H2,1-2H3,(H,31,34);3-4,9-14,33H,5-8,15H2,1-2H3,(H,30,34);4-7,12-15H,8-11H2,1-3H3,(H,29,33)
InChIKeyRFVAQZWYINCCCI-UHFFFAOYSA-N
XLogP25.55
TPSA466.58 Ų
H-Bond Donors9
H-Bond Acceptors35
Rotatable Bonds33
Heavy Atoms216
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002998.17
LogP ≤ 525.55
H-Bond Donors ≤ 59
H-Bond Acceptors ≤ 1035

Analyze 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide with MolForge

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Related Compounds

N-[3-[(4aR,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;N-[3-[(4aS,6R)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl]pyridine-4-carboxamide;2-(2-fluoropropan-2-yl)-N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;N-[5-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl)-6-methyl-3-pyridinyl]-3-(trifluoromethyl)benzamide
CID 157840352
N-[3-[(4aS,6S)-6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-5-(trifluoromethyl)pyridine-3-carboxamide;N-[3-(6-amino-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[5-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-6-methyl-3-pyridinyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-(6-hydroxy-6-methyl-2,4,4a,5-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]pyridine-4-carboxamide;N-[3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide;N-[3-(6-hydroxy-6-methyl-2,4,4a,5-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 158017695
4-(2-aminoethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;4-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-[1-methyl-5-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)-6-oxo-3-pyridinyl]phenyl]pyridine-4-carboxamide;4-(1,2-dihydroxyethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-3-(trifluoromethyl)benzamide;2-[2-hydroxyethyl(methyl)amino]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;2-[methyl-[2-(methylamino)ethyl]amino]-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-[1-methyl-5-(6-oxa-3-azabicyclo[3.1.1]heptan-3-yl)-6-oxo-3-pyridinyl]phenyl]-3-(trifluoromethyl)benzamide
CID 158802798
2-amino-8-N-[6-[[4-[(3-amino-2,2-difluoropropyl)carbamoyl]phenyl]methyl]-7,8-dihydro-5H-1,6-naphthyridin-3-yl]-4-N,4-N-dipropyl-3H-1-benzazepine-4,8-dicarboxamide;2-amino-8-N-[5-(4-amino-3-oxobutyl)-3-pyridinyl]-4-N,4-N-dipropyl-3H-1-benzazepine-4,8-dicarboxamide;2-amino-7-fluoro-4-N,4-N-dipropyl-8-N-(5,6,7,8-tetrahydro-1,6-naphthyridin-3-yl)-3H-1-benzazepine-4,8-dicarboxamide;2-amino-7-(hydroxymethyl)-4-N,4-N-dipropyl-8-N-(5,6,7,8-tetrahydro-1,6-naphthyridin-3-yl)-3H-1-benzazepine-4,8-dicarboxamide
CID 159090108
1-[4-(difluoromethyl)-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone;1-[4-(fluoromethyl)-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone;1-[4-(hydroxymethyl)-3-(2-morpholin-4-yl-4-pyridinyl)phenyl]-2-[3-(trifluoromethyl)phenyl]ethanone;N-[4-methyl-3-[2-morpholin-4-yl-6-(oxan-4-yl)-4-pyridinyl]phenyl]-3-(trifluoromethyl)benzamide
CID 159488544
4-[2-amino-5-(oxan-4-yl)-3-pyridinyl]-N-benzylbenzamide;4-[2-amino-5-(oxan-4-yl)-3-pyridinyl]-N-[[3-(dimethylamino)phenyl]methyl]benzamide;4-[2-amino-5-(oxan-4-yl)-3-pyridinyl]-2-fluoro-N-(pyrazin-2-ylmethyl)benzamide;4-[2-amino-5-(oxan-4-yl)-3-pyridinyl]-N-[(1S)-2-hydroxy-1-phenylethyl]-2-(trifluoromethyl)benzamide
CID 159765726
3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;2-tert-butyl-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide
CID 159857841
2-(1-cyanocyclopropyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;2-(2-cyanopropan-2-yl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(difluoromethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]benzamide;2-(difluoromethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;1-ethyl-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-6-oxo-5-(trifluoromethyl)pyridine-3-carboxamide;2-(2-hydroxypropan-2-yl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-propan-2-ylpyridine-4-carboxamide;N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
CID 160253145
N-[3-[(4aR,6R)-5,5-difluoro-6-hydroxy-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;N-[3-[(4aR,6R)-6-hydroxy-5,5-dimethyl-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl]-4-methylphenyl]-2-(1,1-difluoroethyl)pyridine-4-carboxamide;2-(1,1-difluoroethyl)-N-[3-[6-fluoro-5-(hydroxymethyl)-1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]pyridine-4-carboxamide;bis(2-(1,1-difluoroethyl)-N-[3-[5-fluoro-5-(hydroxymethyl)-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a]quinolin-9-yl]-4-methylphenyl]pyridine-4-carboxamide);2-(1,1-difluoroethyl)-N-[3-(6-hydroxy-5,5-dimethyl-2,4,4a,6-tetrahydro-1H-[1,4]oxazino[4,3-a][1,5]naphthyridin-9-yl)-4-methylphenyl]pyridine-4-carboxamide
CID 160361279
CID 160369093
CID 160369093
2-amino-8-N-[6-[[4-[(3-amino-2,2-difluoropropyl)carbamoyl]phenyl]methyl]-7,8-dihydro-5H-1,6-naphthyridin-3-yl]-4-N,4-N-dipropyl-3H-1-benzazepine-4,8-dicarboxamide;2-amino-8-N-[5-(4-amino-3-oxobutyl)-3-pyridinyl]-4-N,4-N-dipropyl-3H-1-benzazepine-4,8-dicarboxamide;2-amino-7-fluoro-4-N,4-N-dipropyl-8-N-(5,6,7,8-tetrahydro-1,6-naphthyridin-3-yl)-3H-1-benzazepine-4,8-dicarboxamide;2-amino-7-(hydroxymethyl)-4-N,4-N-dipropyl-8-N-(5,6,7,8-tetrahydro-1,6-naphthyridin-3-yl)-3H-1-benzazepine-4,8-dicarboxamide;methane
CID 160683632
2-[(3R,6S)-3-amino-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]propan-2-ol;2-[(3S,6S)-3-amino-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]propan-2-ol;(3S,6S)-3-(carbamoylamino)-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidine-3-carboxamide;N-methyl-2-[(3S,6S)-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]acetamide;N-methyl-2-[(3R,6S)-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]acetamide;(3S,6S)-6-[[(1R)-1-[3-methyl-5-(trifluoromethyl)phenyl]ethoxy]methyl]-3-(2-oxo-2-pyridin-2-ylethyl)-6-phenylpiperidine-3-carboxamide
CID 160715548

Frequently Asked Questions

What is the IUPAC name of 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide?
The IUPAC name of 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide (CID 160613806) is 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide.
What is the SMILES notation for 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide?
The canonical SMILES for 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide is CCCc1ccc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc1C(F)(F)F.CNCc1cc(C(=O)Nc2ccc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)cc(C(F)(F)F)c1.Cc1ccc(C(=O)Cc2ccc(CN)c(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CN)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2cc(CO)cc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)c1.Cc1ccc(NC(=O)c2ccnc(C(C)(F)F)c2)cc1-c1cc(N2CCOCC2)n(C)c(=O)c1.
What is the InChIKey of 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide?
The InChIKey is RFVAQZWYINCCCI-UHFFFAOYSA-N. The full InChI is InChI=1S/C28H30F3N3O3.C27H29F3N4O3.C27H28F3N3O3.C26H27F3N4O3.C26H26F3N3O4.C25H26F2N4O3/c1-4-5-19-7-8-20(14-24(19)28(29,30)31)26(35)32-22-9-6-18(2)23(16-22)21-15-25(27(36)33(3)17-21)34-10-12-37-13-11-34;1-17-4-5-22(32-25(35)19-10-18(15-31-2)11-21(12-19)27(28,29)30)14-23(17)20-13-24(26(36)33(3)16-20)34-6-8-37-9-7-34;1-17-3-5-19(25(34)12-18-4-6-20(15-31)23(11-18)27(28,29)30)13-22(17)21-14-24(26(35)32(2)16-21)33-7-9-36-10-8-33;1-16-3-4-21(31-24(34)18-9-17(14-30)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)32(2)15-19)33-5-7-36-8-6-33;1-16-3-4-21(30-24(34)18-9-17(15-33)10-20(11-18)26(27,28)29)13-22(16)19-12-23(25(35)31(2)14-19)32-5-7-36-8-6-32;1-16-4-5-19(29-24(33)17-6-7-28-21(12-17)25(2,26)27)15-20(16)18-13-22(30(3)23(32)14-18)31-8-10-34-11-9-31/h6-9,14-17H,4-5,10-13H2,1-3H3,(H,32,35);4-5,10-14,16,31H,6-9,15H2,1-3H3,(H,32,35);3-6,11,13-14,16H,7-10,12,15,31H2,1-2H3;3-4,9-13,15H,5-8,14,30H2,1-2H3,(H,31,34);3-4,9-14,33H,5-8,15H2,1-2H3,(H,30,34);4-7,12-15H,8-11H2,1-3H3,(H,29,33).
What are the key properties of 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide?
3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide has a molecular weight of 2998.17 g/mol, XLogP of 25.55, 33 rotatable bonds, 9 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 3-(aminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;5-[5-[2-[4-(aminomethyl)-3-(trifluoromethyl)phenyl]acetyl]-2-methylphenyl]-1-methyl-3-morpholin-4-ylpyridin-2-one;2-(1,1-difluoroethyl)-N-[4-methyl-3-(1-methyl-2-morpholin-4-yl-6-oxo-4-pyridinyl)phenyl]pyridine-4-carboxamide;3-(hydroxymethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;3-(methylaminomethyl)-N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-5-(trifluoromethyl)benzamide;N-[4-methyl-3-(1-methyl-5-morpholin-4-yl-6-oxo-3-pyridinyl)phenyl]-4-propyl-3-(trifluoromethyl)benzamide is sourced from PubChem (CID 160613806), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).