2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one

C195H156Cl10F11N51O14S3 — CID 160626205

IUPAC2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
SMILESCN1C(=O)C(c2cc(Cl)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(Cl)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1
InChIInChI=1S/C21H18ClFN6O.C20H15ClF2N6O.C20H16ClFN4O2.C20H16ClFN4OS.C19H16ClFN6O.3C19H15ClFN5O2.2C19H15ClFN5OS/c1-12-26-10-14(11-27-12)13-5-16(7-17(22)6-13)21(19(30)29(2)20(24)28-21)15-3-4-25-18(8-15)9-23;1-29-17(30)20(28-19(29)24,13-2-3-25-16(7-13)8-22)14-4-11(5-15(21)6-14)12-9-26-18(23)27-10-12;2*1-26-18(27)20(25-19(26)23,14-2-4-24-17(9-14)10-22)15-6-13(7-16(21)8-15)12-3-5-28-11-12;1-27-17(28)19(25-18(27)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-24-26-16;1-26-17(27)19(24-18(26)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-28-25-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16/h3-8,10-11H,9H2,1-2H3,(H2,24,28);2-7,9-10H,8H2,1H3,(H2,24,28);2*2-9,11H,10H2,1H3,(H2,23,25);2-9H,10H2,1H3,(H2,22,25)(H,24,26);2-9H,10H2,1H3,(H2,22,24);4*2-7,9-10H,8H2,1H3,(H2,22,25)
InChIKeyRHIFKFDURIUPEH-UHFFFAOYSA-N
MW4097.44 g/mol
LogP31.30
Rot. Bonds40

About 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one

2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one (PubChem CID 160626205) has the molecular formula C195H156Cl10F11N51O14S3 and a molecular weight of 4097.44 g/mol. Its IUPAC name is 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one.

Molecular Properties

Compound Name2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
PubChem CID160626205
Molecular FormulaC195H156Cl10F11N51O14S3
Molecular Weight4097.44 g/mol
Exact Mass4089.89
IUPAC Name2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one
SMILESCN1C(=O)C(c2cc(Cl)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(Cl)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1
InChIInChI=1S/C21H18ClFN6O.C20H15ClF2N6O.C20H16ClFN4O2.C20H16ClFN4OS.C19H16ClFN6O.3C19H15ClFN5O2.2C19H15ClFN5OS/c1-12-26-10-14(11-27-12)13-5-16(7-17(22)6-13)21(19(30)29(2)20(24)28-21)15-3-4-25-18(8-15)9-23;1-29-17(30)20(28-19(29)24,13-2-3-25-16(7-13)8-22)14-4-11(5-15(21)6-14)12-9-26-18(23)27-10-12;2*1-26-18(27)20(25-19(26)23,14-2-4-24-17(9-14)10-22)15-6-13(7-16(21)8-15)12-3-5-28-11-12;1-27-17(28)19(25-18(27)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-24-26-16;1-26-17(27)19(24-18(26)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-28-25-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16/h3-8,10-11H,9H2,1-2H3,(H2,24,28);2-7,9-10H,8H2,1H3,(H2,24,28);2*2-9,11H,10H2,1H3,(H2,23,25);2-9H,10H2,1H3,(H2,22,25)(H,24,26);2-9H,10H2,1H3,(H2,22,24);4*2-7,9-10H,8H2,1H3,(H2,22,25)
InChIKeyRHIFKFDURIUPEH-UHFFFAOYSA-N
XLogP31.30
TPSA913.05 Ų
H-Bond Donors11
H-Bond Acceptors57
Rotatable Bonds40
Heavy Atoms284
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5004097.44
LogP ≤ 531.30
H-Bond Donors ≤ 511
H-Bond Acceptors ≤ 1057

Analyze 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The IUPAC name of 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one (CID 160626205) is 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one.
What is the SMILES notation for 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The canonical SMILES for 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one is CN1C(=O)C(c2cc(Cl)cc(-c3ccn[nH]3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccoc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccon3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3ccsc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnc(F)nc3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cnco3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cncs3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cocn3)c2)(c2ccnc(CF)c2)N=C1N.CN1C(=O)C(c2cc(Cl)cc(-c3cscn3)c2)(c2ccnc(CF)c2)N=C1N.Cc1ncc(-c2cc(Cl)cc(C3(c4ccnc(CF)c4)N=C(N)N(C)C3=O)c2)cn1.
What is the InChIKey of 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
The InChIKey is RHIFKFDURIUPEH-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H18ClFN6O.C20H15ClF2N6O.C20H16ClFN4O2.C20H16ClFN4OS.C19H16ClFN6O.3C19H15ClFN5O2.2C19H15ClFN5OS/c1-12-26-10-14(11-27-12)13-5-16(7-17(22)6-13)21(19(30)29(2)20(24)28-21)15-3-4-25-18(8-15)9-23;1-29-17(30)20(28-19(29)24,13-2-3-25-16(7-13)8-22)14-4-11(5-15(21)6-14)12-9-26-18(23)27-10-12;2*1-26-18(27)20(25-19(26)23,14-2-4-24-17(9-14)10-22)15-6-13(7-16(21)8-15)12-3-5-28-11-12;1-27-17(28)19(25-18(27)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-24-26-16;1-26-17(27)19(24-18(26)22,12-2-4-23-15(9-12)10-21)13-6-11(7-14(20)8-13)16-3-5-28-25-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16;1-26-17(27)19(25-18(26)22,12-2-3-24-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-23-10-28-16;1-26-17(27)19(25-18(26)22,12-2-3-23-15(7-12)8-21)13-4-11(5-14(20)6-13)16-9-28-10-24-16/h3-8,10-11H,9H2,1-2H3,(H2,24,28);2-7,9-10H,8H2,1H3,(H2,24,28);2*2-9,11H,10H2,1H3,(H2,23,25);2-9H,10H2,1H3,(H2,22,25)(H,24,26);2-9H,10H2,1H3,(H2,22,24);4*2-7,9-10H,8H2,1H3,(H2,22,25).
What are the key properties of 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one?
2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one has a molecular weight of 4097.44 g/mol, XLogP of 31.30, 40 rotatable bonds, 11 hydrogen bond donors, and 57 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[3-chloro-5-(2-fluoropyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(furan-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(2-methylpyrimidin-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,2-oxazol-3-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-oxazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1H-pyrazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-4-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-[3-chloro-5-(1,3-thiazol-5-yl)phenyl]-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one;2-amino-5-(3-chloro-5-thiophen-3-ylphenyl)-5-[2-(fluoromethyl)-4-pyridinyl]-3-methylimidazol-4-one is sourced from PubChem (CID 160626205), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).