2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine

C102H73Cl2F16N25 — CID 160639516

About 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine

2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine (PubChem CID 160639516) has the molecular formula C102H73Cl2F16N25 and a molecular weight of 2023.75 g/mol. Its IUPAC name is 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine.

Molecular Properties

• Compound Name: 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine
• PubChem CID: 160639516
• Molecular Formula: C102H73Cl2F16N25
• Molecular Weight: 2023.75 g/mol
• Exact Mass: 2021.56
• IUPAC Name: 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine
• SMILES: Cc1ccc2nc(C)n(-c3cncc(Nc4ccc(C(F)(F)F)cc4)n3)c2c1.Cc1nc(C)n(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)c1C.Cc1nc2cc(Cl)ccc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ccc(Cl)cc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C3CC3)nc3ccc(F)cn23)c1
• InChI: InChI=1S/C23H15F4N5.2C21H13ClF3N5.C20H16F3N5.C17H16F3N5/c24-16-5-8-20-31-21(14-1-2-14)22(32(20)12-16)18-9-13(11-28)10-19(30-18)29-17-6-3-15(4-7-17)23(25,26)27;1-12-27-17-10-15(22)4-7-18(17)30(12)20-9-13(11-26)8-19(29-20)28-16-5-2-14(3-6-16)21(23,24)25;1-12-27-17-7-4-15(22)10-18(17)30(12)20-9-13(11-26)8-19(29-20)28-16-5-2-14(3-6-16)21(23,24)25;1-12-3-8-16-17(9-12)28(13(2)25-16)19-11-24-10-18(27-19)26-15-6-4-14(5-7-15)20(21,22)23;1-10-11(2)25(12(3)22-10)16-9-21-8-15(24-16)23-14-6-4-13(5-7-14)17(18,19)20/h3-10,12,14H,1-2H2,(H,29,30);2*2-10H,1H3,(H,28,29);3-11H,1-2H3,(H,26,27);4-9H,1-3H3,(H,23,24)
• InChIKey: RIZJSUQWFAJJHN-UHFFFAOYSA-N
• XLogP: 27.62
• TPSA: 310.33 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 25
• Rotatable Bonds: 16
• Heavy Atoms: 145
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2023.75
LogP ≤ 5	27.62
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	25

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine?

The IUPAC name of 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine (CID 160639516) is 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine.

What is the SMILES notation for 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine?

The canonical SMILES for 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine is Cc1ccc2nc(C)n(-c3cncc(Nc4ccc(C(F)(F)F)cc4)n3)c2c1.Cc1nc(C)n(-c2cncc(Nc3ccc(C(F)(F)F)cc3)n2)c1C.Cc1nc2cc(Cl)ccc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.Cc1nc2ccc(Cl)cc2n1-c1cc(C#N)cc(Nc2ccc(C(F)(F)F)cc2)n1.N#Cc1cc(Nc2ccc(C(F)(F)F)cc2)nc(-c2c(C3CC3)nc3ccc(F)cn23)c1.

What is the InChIKey of 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine?

The InChIKey is RIZJSUQWFAJJHN-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H15F4N5.2C21H13ClF3N5.C20H16F3N5.C17H16F3N5/c24-16-5-8-20-31-21(14-1-2-14)22(32(20)12-16)18-9-13(11-28)10-19(30-18)29-17-6-3-15(4-7-17)23(25,26)27;1-12-27-17-10-15(22)4-7-18(17)30(12)20-9-13(11-26)8-19(29-20)28-16-5-2-14(3-6-16)21(23,24)25;1-12-27-17-7-4-15(22)10-18(17)30(12)20-9-13(11-26)8-19(29-20)28-16-5-2-14(3-6-16)21(23,24)25;1-12-3-8-16-17(9-12)28(13(2)25-16)19-11-24-10-18(27-19)26-15-6-4-14(5-7-15)20(21,22)23;1-10-11(2)25(12(3)22-10)16-9-21-8-15(24-16)23-14-6-4-13(5-7-14)17(18,19)20/h3-10,12,14H,1-2H2,(H,29,30);2*2-10H,1H3,(H,28,29);3-11H,1-2H3,(H,26,27);4-9H,1-3H3,(H,23,24).

What are the key properties of 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine?

2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine has a molecular weight of 2023.75 g/mol, XLogP of 27.62, 16 rotatable bonds, 5 hydrogen bond donors, and 25 hydrogen bond acceptors.

Where does this data come from?

All data for 2-(5-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(6-chloro-2-methylbenzimidazol-1-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;2-(2-cyclopropyl-6-fluoroimidazo[1,2-a]pyridin-3-yl)-6-[4-(trifluoromethyl)anilino]pyridine-4-carbonitrile;6-(2,6-dimethylbenzimidazol-1-yl)-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amine;N-[4-(trifluoromethyl)phenyl]-6-(2,4,5-trimethylimidazol-1-yl)pyrazin-2-amine is sourced from PubChem (CID 160639516), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).