8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one

C147H131F9N26O17 — CID 160639918

IUPAC8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one
SMILESCC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cc[nH]c(=O)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(C(F)(F)F)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(F)c2)n1.COc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1.Cc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1
InChIInChI=1S/C30H25F4N5O3.C30H28FN5O4.C30H28FN5O3.C29H25F2N5O3.C28H25FN6O4/c1-29(2,3)25-14-20(39(38-25)19-6-4-5-18(12-19)30(32,33)34)13-21(40)11-17-7-8-22(15-23(17)31)42-24-9-10-35-28-27(24)36-16-26(41)37-28;1-30(2,3)26-15-20(36(35-26)19-6-5-7-22(14-19)39-4)13-21(37)12-18-8-9-23(16-24(18)31)40-25-10-11-32-29-28(25)33-17-27(38)34-29;1-18-6-5-7-20(12-18)36-21(15-26(35-36)30(2,3)4)14-22(37)13-19-8-9-23(16-24(19)31)39-25-10-11-32-29-28(25)33-17-27(38)34-29;1-29(2,3)25-14-20(36(35-25)19-6-4-5-18(30)12-19)13-21(37)11-17-7-8-22(15-23(17)31)39-24-9-10-32-28-27(24)33-16-26(38)34-28;1-28(2,3)23-12-18(35(34-23)17-6-8-30-24(37)13-17)11-19(36)10-16-4-5-20(14-21(16)29)39-22-7-9-31-27-26(22)32-15-25(38)33-27/h4-10,12,14-16H,11,13H2,1-3H3,(H,35,37,41);5-11,14-17H,12-13H2,1-4H3,(H,32,34,38);5-12,15-17H,13-14H2,1-4H3,(H,32,34,38);4-10,12,14-16H,11,13H2,1-3H3,(H,32,34,38);4-9,12-15H,10-11H2,1-3H3,(H,30,37)(H,31,33,38)
InChIKeyRJARJPIINBHBHK-UHFFFAOYSA-N
MW2704.81 g/mol
LogP25.60
Rot. Bonds36

About 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one

8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one (PubChem CID 160639918) has the molecular formula C147H131F9N26O17 and a molecular weight of 2704.81 g/mol. Its IUPAC name is 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one.

Molecular Properties

Compound Name8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one
PubChem CID160639918
Molecular FormulaC147H131F9N26O17
Molecular Weight2704.81 g/mol
Exact Mass2703.00
IUPAC Name8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one
SMILESCC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cc[nH]c(=O)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(C(F)(F)F)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(F)c2)n1.COc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1.Cc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1
InChIInChI=1S/C30H25F4N5O3.C30H28FN5O4.C30H28FN5O3.C29H25F2N5O3.C28H25FN6O4/c1-29(2,3)25-14-20(39(38-25)19-6-4-5-18(12-19)30(32,33)34)13-21(40)11-17-7-8-22(15-23(17)31)42-24-9-10-35-28-27(24)36-16-26(41)37-28;1-30(2,3)26-15-20(36(35-26)19-6-5-7-22(14-19)39-4)13-21(37)12-18-8-9-23(16-24(18)31)40-25-10-11-32-29-28(25)33-17-27(38)34-29;1-18-6-5-7-20(12-18)36-21(15-26(35-36)30(2,3)4)14-22(37)13-19-8-9-23(16-24(19)31)39-25-10-11-32-29-28(25)33-17-27(38)34-29;1-29(2,3)25-14-20(36(35-25)19-6-4-5-18(30)12-19)13-21(37)11-17-7-8-22(15-23(17)31)39-24-9-10-32-28-27(24)33-16-26(38)34-28;1-28(2,3)23-12-18(35(34-23)17-6-8-30-24(37)13-17)11-19(36)10-16-4-5-20(14-21(16)29)39-22-7-9-31-27-26(22)32-15-25(38)33-27/h4-10,12,14-16H,11,13H2,1-3H3,(H,35,37,41);5-11,14-17H,12-13H2,1-4H3,(H,32,34,38);5-12,15-17H,13-14H2,1-4H3,(H,32,34,38);4-10,12,14-16H,11,13H2,1-3H3,(H,32,34,38);4-9,12-15H,10-11H2,1-3H3,(H,30,37)(H,31,33,38)
InChIKeyRJARJPIINBHBHK-UHFFFAOYSA-N
XLogP25.60
TPSA555.89 Ų
H-Bond Donors6
H-Bond Acceptors37
Rotatable Bonds36
Heavy Atoms199
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002704.81
LogP ≤ 525.60
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1037

Analyze 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

(3S)-3-[4-[2-[2-[2-[2-[4-[1,1-bis[1-[2-[2-[2-[2-[4-[(1S)-2-carboxy-1-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]imidazolidin-1-yl]ethyl]-2-fluorophenoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]ethyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]-3-fluorophenyl]-3-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]imidazolidin-1-yl]propanoic acid
CID 156666081
CID 157694736
CID 157694736
1-[3-(ethylamino)-3-oxopropyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;1-[3-(methylamino)-3-oxopropyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;methyl 4-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]benzoate;2-[2-oxo-5-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]-1-pyridinyl]acetic acid;3-[3-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]phenyl]propanoic acid;N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-4-(trifluoromethoxy)benzamide
CID 157731368
1-[2-(cyclopropylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;ethyl 1-[3-[[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]carbamoyl]phenyl]piperidine-3-carboxylate;3-[4-(2-methoxyethyl)piperazin-1-yl]-N-[5-[3-(6-methoxy-3-pyridinyl)-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;3-[4-(2-methoxyethyl)piperazin-1-yl]-N-[5-[3-(oxan-4-yl)-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]benzamide;1-[2-(2-morpholin-4-ylethylamino)-2-oxoethyl]-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide
CID 158442339
3-tert-butyl-N-[3-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]benzamide;1-[3-tert-butyl-1-(4-methylphenyl)pyrazol-5-yl]-3-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea;1-(3-tert-butyl-1-phenylpyrazol-5-yl)-3-[4-[(2-methyl-3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea;1-(3-tert-butyl-1-phenylpyrazol-5-yl)-3-[4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]naphthalen-1-yl]urea;1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[3-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea
CID 158603289
5-(4-fluorophenyl)-N-(2-methyl-4-pyridinyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-[3-(4-methylpiperazin-1-yl)propyl]-4-[[5-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;N-(1-methylpiperidin-4-yl)-4-[[5-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;N-methyl-4-[[5-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide;N-(4-morpholin-4-ylphenyl)-5-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine;N-(piperidin-4-ylmethyl)-4-[[5-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]amino]benzamide
CID 158851980
1-[4-[6-(2-cyclopropyl-2-oxoethyl)pyridazin-3-yl]butyl]-N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]triazole-4-carboxamide;N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]-1-[4-[6-[(2-pyridin-4-ylacetyl)amino]pyridazin-3-yl]butyl]triazole-4-carboxamide;1-[3-fluoro-4-[4-[3-(3-fluoroazetidin-1-yl)-2-oxopropyl]triazol-1-yl]butyl]-N-[(2-fluoro-5-methylphenyl)methyl]triazole-4-carboxamide;1-[4-[4-[3-(4-fluoro-4-methylpiperidin-1-yl)-2-oxopropyl]triazol-1-yl]butyl]-N-[(3-methylphenyl)methyl]triazole-4-carboxamide;N-[6-[(3R)-3-fluoro-4-(4-propanoyltriazol-1-yl)butyl]pyridazin-3-yl]-2-[1-(3-methylphenyl)imidazol-4-yl]acetamide;N-methyl-1-[4-[6-[2-oxo-3-[1-[3-(trifluoromethoxy)phenyl]imidazol-4-yl]propyl]pyridazin-3-yl]butyl]triazole-4-carboxamide;1-[4-[4-[3-(3-methylphenyl)propanoyl]triazol-1-yl]butyl]-N-[(5-methyl-3-pyridinyl)methyl]triazole-4-carboxamide
CID 159167491
8-[8-[3-[3-tert-butyl-1-(4-methylphenyl)pyrazol-5-yl]-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one;8-[8-[3-[2-fluoro-5-(trifluoromethyl)phenyl]-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one
CID 159375127
N-[6-[4-(4-acetyltriazol-1-yl)butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide;1-[4-[6-(2-cyclopropyl-2-oxoethyl)pyridazin-3-yl]butyl]-N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]triazole-4-carboxamide;N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]-1-[4-[6-[(2-pyridin-2-ylacetyl)amino]pyridazin-3-yl]butyl]triazole-4-carboxamide;N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]-1-[4-[6-[(2-pyridin-3-ylacetyl)amino]pyridazin-3-yl]butyl]triazole-4-carboxamide;N-[[5-(1,1-difluoroethoxy)-2-fluorophenyl]methyl]-1-[4-[6-[(2-pyridin-4-ylacetyl)amino]pyridazin-3-yl]butyl]triazole-4-carboxamide;N-methyl-1-[4-[6-[2-oxo-3-[1-[3-(trifluoromethoxy)phenyl]imidazol-4-yl]propyl]pyridazin-3-yl]butyl]triazole-4-carboxamide;N-methyl-1-[4-[6-[2-oxo-3-[4-[2-(trifluoromethyl)phenyl]-2-pyridinyl]propyl]pyridazin-3-yl]butyl]triazole-4-carboxamide
CID 159438572
8-[8-[3-[3-tert-butyl-1-(4-methylphenyl)pyrazol-5-yl]-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one;4-[8-[3-(3-tert-butyl-1-methylpyrazol-5-yl)-2-oxopropyl]quinolin-5-yl]oxy-1-methyl-3H-pyrrolo[2,3-b]pyridin-2-one;4-[8-[3-(3-tert-butylphenyl)-2-oxopropyl]quinolin-5-yl]oxy-1-methyl-3H-pyrrolo[2,3-b]pyridin-2-one;4-[8-[3-(3-tert-butyl-1-phenylpyrazol-5-yl)-2-oxopropyl]quinolin-5-yl]oxy-1-methyl-3H-pyrrolo[2,3-b]pyridin-2-one;8-[8-[3-[2-fluoro-5-(trifluoromethyl)phenyl]-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one
CID 159597780
1-benzyl-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]pyridine-3-carboxamide;6-ethoxy-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]pyridine-3-carboxamide;3-(6-fluoro-3-pyridinyl)-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;4-morpholin-4-yl-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]benzamide;6-morpholin-4-yl-N-[6-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridazin-3-yl]pyridine-3-carboxamide;6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]-2-pyridinyl]-1-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide
CID 159961068
8-[8-[3-[3-tert-butyl-1-(4-methylphenyl)pyrazol-5-yl]-2-oxopropyl]quinolin-5-yl]oxy-4H-pyrido[2,3-b]pyrazin-3-one;8-[8-[3-(3-tert-butyl-1-methylpyrazol-5-yl)-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one;8-[8-[3-(3-tert-butyl-1-phenylpyrazol-5-yl)-2-oxopropyl]quinolin-5-yl]oxy-2-methyl-4H-pyrido[2,3-b]pyrazin-3-one;5-[8-[3-[2-fluoro-5-(trifluoromethyl)phenyl]-2-oxopropyl]quinolin-5-yl]oxy-4H-1,8-naphthyridin-3-one;8-[8-[3-[2-fluoro-5-(trifluoromethyl)phenyl]-2-oxopropyl]quinolin-5-yl]oxy-4H-pyrido[2,3-b]pyrazin-3-one
CID 160180208

Frequently Asked Questions

What is the IUPAC name of 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one?
The IUPAC name of 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one (CID 160639918) is 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one.
What is the SMILES notation for 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one?
The canonical SMILES for 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one is CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cc[nH]c(=O)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(C(F)(F)F)c2)n1.CC(C)(C)c1cc(CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)n(-c2cccc(F)c2)n1.COc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1.Cc1cccc(-n2nc(C(C)(C)C)cc2CC(=O)Cc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2F)c1.
What is the InChIKey of 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one?
The InChIKey is RJARJPIINBHBHK-UHFFFAOYSA-N. The full InChI is InChI=1S/C30H25F4N5O3.C30H28FN5O4.C30H28FN5O3.C29H25F2N5O3.C28H25FN6O4/c1-29(2,3)25-14-20(39(38-25)19-6-4-5-18(12-19)30(32,33)34)13-21(40)11-17-7-8-22(15-23(17)31)42-24-9-10-35-28-27(24)36-16-26(41)37-28;1-30(2,3)26-15-20(36(35-26)19-6-5-7-22(14-19)39-4)13-21(37)12-18-8-9-23(16-24(18)31)40-25-10-11-32-29-28(25)33-17-27(38)34-29;1-18-6-5-7-20(12-18)36-21(15-26(35-36)30(2,3)4)14-22(37)13-19-8-9-23(16-24(19)31)39-25-10-11-32-29-28(25)33-17-27(38)34-29;1-29(2,3)25-14-20(36(35-25)19-6-4-5-18(30)12-19)13-21(37)11-17-7-8-22(15-23(17)31)39-24-9-10-32-28-27(24)33-16-26(38)34-28;1-28(2,3)23-12-18(35(34-23)17-6-8-30-24(37)13-17)11-19(36)10-16-4-5-20(14-21(16)29)39-22-7-9-31-27-26(22)32-15-25(38)33-27/h4-10,12,14-16H,11,13H2,1-3H3,(H,35,37,41);5-11,14-17H,12-13H2,1-4H3,(H,32,34,38);5-12,15-17H,13-14H2,1-4H3,(H,32,34,38);4-10,12,14-16H,11,13H2,1-3H3,(H,32,34,38);4-9,12-15H,10-11H2,1-3H3,(H,30,37)(H,31,33,38).
What are the key properties of 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one?
8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one has a molecular weight of 2704.81 g/mol, XLogP of 25.60, 36 rotatable bonds, 6 hydrogen bond donors, and 37 hydrogen bond acceptors.
Where does this data come from?
All data for 8-[4-[3-[3-tert-butyl-1-(3-fluorophenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methoxyphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(3-methylphenyl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-(2-oxo-1H-pyridin-4-yl)pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one;8-[4-[3-[3-tert-butyl-1-[3-(trifluoromethyl)phenyl]pyrazol-5-yl]-2-oxopropyl]-3-fluorophenoxy]-4H-pyrido[2,3-b]pyrazin-3-one is sourced from PubChem (CID 160639918), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).