tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

C274H375N35O32 — CID 160648880

IUPACtert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCCC1(N(C)C)CCC2(CC1)CN(Cc1ccc(OC)cc1)C(=O)N2.COCCNC(=O)CN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCOc1ccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)cc1.COCOc1cccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)c1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N(C)C)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N3CCCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)O)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)OC(C)(C)C)C2=O)cc1
InChIInChI=1S/C31H43N3O4.C30H40N4O3.C29H40N4O4.C28H38N4O3.C28H38N4O2.C27H36N4O.C27H35N3O4.2C26H35N3O4.C22H35N3O3/c1-29(2,3)38-27(35)16-21-34-28(36)33(22-24-12-14-26(37-6)15-13-24)23-30(34)17-19-31(20-18-30,32(4)5)25-10-8-7-9-11-25;1-31(2)30(25-9-5-4-6-10-25)17-15-29(16-18-30)23-33(21-24-11-13-26(37-3)14-12-24)28(36)34(29)22-27(35)32-19-7-8-20-32;1-31(2)29(24-8-6-5-7-9-24)16-14-28(15-17-29)22-32(20-23-10-12-25(37-4)13-11-23)27(35)33(28)21-26(34)30-18-19-36-3;1-29(2)25(33)20-32-26(34)31(19-22-11-13-24(35-5)14-12-22)21-27(32)15-17-28(18-16-27,30(3)4)23-9-7-6-8-10-23;1-30(2)28(24-10-5-4-6-11-24)16-14-27(15-17-28)21-31(19-23-12-13-25(34-3)29-18-23)26(33)32(27)20-22-8-7-9-22;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-28(2)27(22-7-5-4-6-8-22)16-14-26(15-17-27)20-29(25(33)30(26)18-13-24(31)32)19-21-9-11-23(34-3)12-10-21;1-28(2)26(21-7-11-23(12-8-21)33-19-31-3)15-13-25(14-16-26)18-29(24(30)27-25)17-20-5-9-22(32-4)10-6-20;1-28(2)26(21-6-5-7-23(16-21)33-19-31-3)14-12-25(13-15-26)18-29(24(30)27-25)17-20-8-10-22(32-4)11-9-20;1-24(2)22(10-5-15-27-3)13-11-21(12-14-22)17-25(20(26)23-21)16-18-6-8-19(28-4)9-7-18/h7-15H,16-23H2,1-6H3;4-6,9-14H,7-8,15-23H2,1-3H3;5-13H,14-22H2,1-4H3,(H,30,34);6-14H,15-21H2,1-5H3;4-6,10-13,18,22H,7-9,14-17,19-21H2,1-3H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-12H,13-20H2,1-3H3,(H,31,32);5-12H,13-19H2,1-4H3,(H,27,30);5-11,16H,12-15,17-19H2,1-4H3,(H,27,30);6-9H,5,10-17H2,1-4H3,(H,23,26)
InChIKeyRKDQOCGJNHTISX-UHFFFAOYSA-N
MW4671.23 g/mol
LogP42.19
Rot. Bonds77

About tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one

tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (PubChem CID 160648880) has the molecular formula C274H375N35O32 and a molecular weight of 4671.23 g/mol. Its IUPAC name is tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.

Molecular Properties

Compound Nametert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
PubChem CID160648880
Molecular FormulaC274H375N35O32
Molecular Weight4671.23 g/mol
Exact Mass4667.88
IUPAC Nametert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one
SMILESCN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCCC1(N(C)C)CCC2(CC1)CN(Cc1ccc(OC)cc1)C(=O)N2.COCCNC(=O)CN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCOc1ccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)cc1.COCOc1cccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)c1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N(C)C)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N3CCCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)O)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)OC(C)(C)C)C2=O)cc1
InChIInChI=1S/C31H43N3O4.C30H40N4O3.C29H40N4O4.C28H38N4O3.C28H38N4O2.C27H36N4O.C27H35N3O4.2C26H35N3O4.C22H35N3O3/c1-29(2,3)38-27(35)16-21-34-28(36)33(22-24-12-14-26(37-6)15-13-24)23-30(34)17-19-31(20-18-30,32(4)5)25-10-8-7-9-11-25;1-31(2)30(25-9-5-4-6-10-25)17-15-29(16-18-30)23-33(21-24-11-13-26(37-3)14-12-24)28(36)34(29)22-27(35)32-19-7-8-20-32;1-31(2)29(24-8-6-5-7-9-24)16-14-28(15-17-29)22-32(20-23-10-12-25(37-4)13-11-23)27(35)33(28)21-26(34)30-18-19-36-3;1-29(2)25(33)20-32-26(34)31(19-22-11-13-24(35-5)14-12-22)21-27(32)15-17-28(18-16-27,30(3)4)23-9-7-6-8-10-23;1-30(2)28(24-10-5-4-6-11-24)16-14-27(15-17-28)21-31(19-23-12-13-25(34-3)29-18-23)26(33)32(27)20-22-8-7-9-22;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-28(2)27(22-7-5-4-6-8-22)16-14-26(15-17-27)20-29(25(33)30(26)18-13-24(31)32)19-21-9-11-23(34-3)12-10-21;1-28(2)26(21-7-11-23(12-8-21)33-19-31-3)15-13-25(14-16-26)18-29(24(30)27-25)17-20-5-9-22(32-4)10-6-20;1-28(2)26(21-6-5-7-23(16-21)33-19-31-3)14-12-25(13-15-26)18-29(24(30)27-25)17-20-8-10-22(32-4)11-9-20;1-24(2)22(10-5-15-27-3)13-11-21(12-14-22)17-25(20(26)23-21)16-18-6-8-19(28-4)9-7-18/h7-15H,16-23H2,1-6H3;4-6,9-14H,7-8,15-23H2,1-3H3;5-13H,14-22H2,1-4H3,(H,30,34);6-14H,15-21H2,1-5H3;4-6,10-13,18,22H,7-9,14-17,19-21H2,1-3H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-12H,13-20H2,1-3H3,(H,31,32);5-12H,13-19H2,1-4H3,(H,27,30);5-11,16H,12-15,17-19H2,1-4H3,(H,27,30);6-9H,5,10-17H2,1-4H3,(H,23,26)
InChIKeyRKDQOCGJNHTISX-UHFFFAOYSA-N
XLogP42.19
TPSA591.82 Ų
H-Bond Donors5
H-Bond Acceptors43
Rotatable Bonds77
Heavy Atoms341
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5004671.23
LogP ≤ 542.19
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1043

Analyze tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one with MolForge

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What is the IUPAC name of tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The IUPAC name of tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one (CID 160648880) is tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one.
What is the SMILES notation for tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The canonical SMILES for tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is CN(C)C1(c2ccccc2)CCC2(CC1)CN(Cc1cccnc1)C(=O)N2CC1CCC1.COCCCC1(N(C)C)CCC2(CC1)CN(Cc1ccc(OC)cc1)C(=O)N2.COCCNC(=O)CN1C(=O)N(Cc2ccc(OC)cc2)CC12CCC(c1ccccc1)(N(C)C)CC2.COCOc1ccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)cc1.COCOc1cccc(C2(N(C)C)CCC3(CC2)CN(Cc2ccc(OC)cc2)C(=O)N3)c1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N(C)C)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC(=O)N3CCCC3)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CC3CCC3)C2=O)cn1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)O)C2=O)cc1.COc1ccc(CN2CC3(CCC(c4ccccc4)(N(C)C)CC3)N(CCC(=O)OC(C)(C)C)C2=O)cc1.
What is the InChIKey of tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
The InChIKey is RKDQOCGJNHTISX-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H43N3O4.C30H40N4O3.C29H40N4O4.C28H38N4O3.C28H38N4O2.C27H36N4O.C27H35N3O4.2C26H35N3O4.C22H35N3O3/c1-29(2,3)38-27(35)16-21-34-28(36)33(22-24-12-14-26(37-6)15-13-24)23-30(34)17-19-31(20-18-30,32(4)5)25-10-8-7-9-11-25;1-31(2)30(25-9-5-4-6-10-25)17-15-29(16-18-30)23-33(21-24-11-13-26(37-3)14-12-24)28(36)34(29)22-27(35)32-19-7-8-20-32;1-31(2)29(24-8-6-5-7-9-24)16-14-28(15-17-29)22-32(20-23-10-12-25(37-4)13-11-23)27(35)33(28)21-26(34)30-18-19-36-3;1-29(2)25(33)20-32-26(34)31(19-22-11-13-24(35-5)14-12-22)21-27(32)15-17-28(18-16-27,30(3)4)23-9-7-6-8-10-23;1-30(2)28(24-10-5-4-6-11-24)16-14-27(15-17-28)21-31(19-23-12-13-25(34-3)29-18-23)26(33)32(27)20-22-8-7-9-22;1-29(2)27(24-11-4-3-5-12-24)15-13-26(14-16-27)21-30(19-23-10-7-17-28-18-23)25(32)31(26)20-22-8-6-9-22;1-28(2)27(22-7-5-4-6-8-22)16-14-26(15-17-27)20-29(25(33)30(26)18-13-24(31)32)19-21-9-11-23(34-3)12-10-21;1-28(2)26(21-7-11-23(12-8-21)33-19-31-3)15-13-25(14-16-26)18-29(24(30)27-25)17-20-5-9-22(32-4)10-6-20;1-28(2)26(21-6-5-7-23(16-21)33-19-31-3)14-12-25(13-15-26)18-29(24(30)27-25)17-20-8-10-22(32-4)11-9-20;1-24(2)22(10-5-15-27-3)13-11-21(12-14-22)17-25(20(26)23-21)16-18-6-8-19(28-4)9-7-18/h7-15H,16-23H2,1-6H3;4-6,9-14H,7-8,15-23H2,1-3H3;5-13H,14-22H2,1-4H3,(H,30,34);6-14H,15-21H2,1-5H3;4-6,10-13,18,22H,7-9,14-17,19-21H2,1-3H3;3-5,7,10-12,17-18,22H,6,8-9,13-16,19-21H2,1-2H3;4-12H,13-20H2,1-3H3,(H,31,32);5-12H,13-19H2,1-4H3,(H,27,30);5-11,16H,12-15,17-19H2,1-4H3,(H,27,30);6-9H,5,10-17H2,1-4H3,(H,23,26).
What are the key properties of tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one?
tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one has a molecular weight of 4671.23 g/mol, XLogP of 42.19, 77 rotatable bonds, 5 hydrogen bond donors, and 43 hydrogen bond acceptors.
Where does this data come from?
All data for tert-butyl 3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoate;1-(cyclobutylmethyl)-8-(dimethylamino)-3-[(6-methoxy-3-pyridinyl)methyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one;1-(cyclobutylmethyl)-8-(dimethylamino)-8-phenyl-3-(pyridin-3-ylmethyl)-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[3-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-8-[4-(methoxymethoxy)phenyl]-3-[(4-methoxyphenyl)methyl]-1,3-diazaspiro[4.5]decan-2-one;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-8-(3-methoxypropyl)-1,3-diazaspiro[4.5]decan-2-one;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N,N-dimethylacetamide;2-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]-N-(2-methoxyethyl)acetamide;3-[8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-2-oxo-8-phenyl-1,3-diazaspiro[4.5]decan-1-yl]propanoic acid;8-(dimethylamino)-3-[(4-methoxyphenyl)methyl]-1-(2-oxo-2-pyrrolidin-1-ylethyl)-8-phenyl-1,3-diazaspiro[4.5]decan-2-one is sourced from PubChem (CID 160648880), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).