[2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone

C121H152ClF4N25O7 — CID 160664048

About [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone

[2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone (PubChem CID 160664048) has the molecular formula C121H152ClF4N25O7 and a molecular weight of 2180.16 g/mol. Its IUPAC name is [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone.

Molecular Properties

• Compound Name: [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone
• PubChem CID: 160664048
• Molecular Formula: C121H152ClF4N25O7
• Molecular Weight: 2180.16 g/mol
• Exact Mass: 2178.19
• IUPAC Name: [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone
• SMILES: COc1ccccc1CN1CC2(CCN(C(=O)n3cc(C)cn3)CC2)C1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2C(F)(F)F)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2C)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2Cl)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2F)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2N2CCCC2)C3)c1
• InChI: InChI=1S/C23H31N5O.C20H23F3N4O.C20H26N4O2.C20H26N4O.C19H23ClN4O.C19H23FN4O/c1-19-14-24-28(15-19)22(29)27-12-8-23(9-13-27)17-25(18-23)16-20-6-2-3-7-21(20)26-10-4-5-11-26;1-15-10-24-27(11-15)18(28)26-8-6-19(7-9-26)13-25(14-19)12-16-4-2-3-5-17(16)20(21,22)23;1-16-11-21-24(12-16)19(25)23-9-7-20(8-10-23)14-22(15-20)13-17-5-3-4-6-18(17)26-2;1-16-11-21-24(12-16)19(25)23-9-7-20(8-10-23)14-22(15-20)13-18-6-4-3-5-17(18)2;2*1-15-10-21-24(11-15)18(25)23-8-6-19(7-9-23)13-22(14-19)12-16-4-2-3-5-17(16)20/h2-3,6-7,14-15H,4-5,8-13,16-18H2,1H3;2-5,10-11H,6-9,12-14H2,1H3;3-6,11-12H,7-10,13-15H2,1-2H3;3-6,11-12H,7-10,13-15H2,1-2H3;2*2-5,10-11H,6-9,12-14H2,1H3
• InChIKey: RMBBSXATENRIES-UHFFFAOYSA-N
• XLogP: 19.27
• TPSA: 260.69 Ų
• H-Bond Acceptors: 26
• Rotatable Bonds: 14
• Heavy Atoms: 158
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2180.16
LogP ≤ 5	19.27
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	26

Frequently Asked Questions

What is the IUPAC name of [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The IUPAC name of [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone (CID 160664048) is [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone.

What is the SMILES notation for [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The canonical SMILES for [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone is COc1ccccc1CN1CC2(CCN(C(=O)n3cc(C)cn3)CC2)C1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2C(F)(F)F)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2C)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2Cl)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2F)C3)c1.Cc1cnn(C(=O)N2CCC3(CC2)CN(Cc2ccccc2N2CCCC2)C3)c1.

What is the InChIKey of [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

The InChIKey is RMBBSXATENRIES-UHFFFAOYSA-N. The full InChI is InChI=1S/C23H31N5O.C20H23F3N4O.C20H26N4O2.C20H26N4O.C19H23ClN4O.C19H23FN4O/c1-19-14-24-28(15-19)22(29)27-12-8-23(9-13-27)17-25(18-23)16-20-6-2-3-7-21(20)26-10-4-5-11-26;1-15-10-24-27(11-15)18(28)26-8-6-19(7-9-26)13-25(14-19)12-16-4-2-3-5-17(16)20(21,22)23;1-16-11-21-24(12-16)19(25)23-9-7-20(8-10-23)14-22(15-20)13-17-5-3-4-6-18(17)26-2;1-16-11-21-24(12-16)19(25)23-9-7-20(8-10-23)14-22(15-20)13-18-6-4-3-5-17(18)2;2*1-15-10-21-24(11-15)18(25)23-8-6-19(7-9-23)13-22(14-19)12-16-4-2-3-5-17(16)20/h2-3,6-7,14-15H,4-5,8-13,16-18H2,1H3;2-5,10-11H,6-9,12-14H2,1H3;3-6,11-12H,7-10,13-15H2,1-2H3;3-6,11-12H,7-10,13-15H2,1-2H3;2*2-5,10-11H,6-9,12-14H2,1H3.

What are the key properties of [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone?

[2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone has a molecular weight of 2180.16 g/mol, XLogP of 19.27, 14 rotatable bonds, 0 hydrogen bond donors, and 26 hydrogen bond acceptors.

Where does this data come from?

All data for [2-[(2-chlorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-fluorophenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methoxyphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;[2-[(2-methylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]-(4-methylpyrazol-1-yl)methanone;(4-methylpyrazol-1-yl)-[2-[(2-pyrrolidin-1-ylphenyl)methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone;(4-methylpyrazol-1-yl)-[2-[[2-(trifluoromethyl)phenyl]methyl]-2,7-diazaspiro[3.5]nonan-7-yl]methanone is sourced from PubChem (CID 160664048), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).