1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine

C131H98F33N23O8 — CID 160667924

IUPAC1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine
SMILESCC(F)(F)c1nc(C#N)c2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(C4(C#N)CC4)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(OC(F)(F)F)cc3)nn12.CC(F)(F)c1ncc2cnc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.COC(C)(C)c1ccc(-c2ccc3cnc(C(C)(F)F)n3c2)cc1.COc1cc(OC(F)(F)F)ccc1-c1ccc2cnc(C(C)(F)F)n2c1
InChIInChI=1S/C19H15F2N3.C19H20F2N2O.C17H13F5N2O2.C16H9F5N4O.3C15H10F5N3O.C15H11F4N3O/c1-18(20,21)17-23-10-16-7-4-14(11-24(16)17)13-2-5-15(6-3-13)19(12-22)8-9-19;1-18(2,24-4)15-8-5-13(6-9-15)14-7-10-16-11-22-17(19(3,20)21)23(16)12-14;1-16(18,19)15-23-8-11-4-3-10(9-24(11)15)13-6-5-12(7-14(13)25-2)26-17(20,21)22;1-15(17,18)14-24-12(6-22)13-23-7-10(8-25(13)14)9-2-4-11(5-3-9)26-16(19,20)21;1-14(16,17)13-21-8-10-4-7-12(22-23(10)13)9-2-5-11(6-3-9)24-15(18,19)20;1-14(16,17)13-22-7-12-21-6-10(8-23(12)13)9-2-4-11(5-3-9)24-15(18,19)20;1-14(16,17)13-22-7-10-6-21-12(8-23(10)13)9-2-4-11(5-3-9)24-15(18,19)20;1-9(16)14-21-7-13-20-6-11(8-22(13)14)10-2-4-12(5-3-10)23-15(17,18)19/h2-7,10-11H,8-9H2,1H3;5-12H,1-4H3;3-9H,1-2H3;2-5,7-8H,1H3;3*2-8H,1H3;2-9H,1H3
InChIKeyRMNZLBLDLMMWMS-UHFFFAOYSA-N
MW2749.31 g/mol
LogP36.51
Rot. Bonds26

About 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine

1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine (PubChem CID 160667924) has the molecular formula C131H98F33N23O8 and a molecular weight of 2749.31 g/mol. Its IUPAC name is 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine.

Molecular Properties

Compound Name1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine
PubChem CID160667924
Molecular FormulaC131H98F33N23O8
Molecular Weight2749.31 g/mol
Exact Mass2747.74
IUPAC Name1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine
SMILESCC(F)(F)c1nc(C#N)c2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(C4(C#N)CC4)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(OC(F)(F)F)cc3)nn12.CC(F)(F)c1ncc2cnc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.COC(C)(C)c1ccc(-c2ccc3cnc(C(C)(F)F)n3c2)cc1.COc1cc(OC(F)(F)F)ccc1-c1ccc2cnc(C(C)(F)F)n2c1
InChIInChI=1S/C19H15F2N3.C19H20F2N2O.C17H13F5N2O2.C16H9F5N4O.3C15H10F5N3O.C15H11F4N3O/c1-18(20,21)17-23-10-16-7-4-14(11-24(16)17)13-2-5-15(6-3-13)19(12-22)8-9-19;1-18(2,24-4)15-8-5-13(6-9-15)14-7-10-16-11-22-17(19(3,20)21)23(16)12-14;1-16(18,19)15-23-8-11-4-3-10(9-24(11)15)13-6-5-12(7-14(13)25-2)26-17(20,21)22;1-15(17,18)14-24-12(6-22)13-23-7-10(8-25(13)14)9-2-4-11(5-3-9)26-16(19,20)21;1-14(16,17)13-21-8-10-4-7-12(22-23(10)13)9-2-5-11(6-3-9)24-15(18,19)20;1-14(16,17)13-22-7-12-21-6-10(8-23(12)13)9-2-4-11(5-3-9)24-15(18,19)20;1-14(16,17)13-22-7-10-6-21-12(8-23(10)13)9-2-4-11(5-3-9)24-15(18,19)20;1-9(16)14-21-7-13-20-6-11(8-22(13)14)10-2-4-12(5-3-10)23-15(17,18)19/h2-7,10-11H,8-9H2,1H3;5-12H,1-4H3;3-9H,1-2H3;2-5,7-8H,1H3;3*2-8H,1H3;2-9H,1H3
InChIKeyRMNZLBLDLMMWMS-UHFFFAOYSA-N
XLogP36.51
TPSA324.27 Ų
H-Bond Donors
H-Bond Acceptors31
Rotatable Bonds26
Heavy Atoms195
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5002749.31
LogP ≤ 536.51
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 1031

Analyze 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine with MolForge

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Related Compounds

4-[4-[4-[4-[4-(difluoromethyl)phenyl]-5-methyl-1H-imidazol-2-yl]-4-methylpiperidin-1-yl]-7-[[2-[1-[6-[1-(difluoromethyl)pyrazol-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-4-methylpiperidin-4-yl]-4-(3-methoxyphenyl)-1H-imidazol-5-yl]methyl]pyrrolo[2,3-d]pyrimidin-6-yl]benzonitrile
CID 130455743
1-[4-[6-(1,1-Difluoroethyl)imidazo[1,5-a]pyrimidin-3-yl]-3-methoxyphenyl]cyclopropane-1-carbonitrile;1-[4-[6-(1,1-difluoroethyl)imidazo[1,5-a]pyrimidin-3-yl]phenyl]cyclopropane-1-carbonitrile;bis(3-(1,1-difluoroethyl)-6-[2-(methoxymethyl)-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine);3-(1,1-difluoroethyl)-6-[2-(methoxymethyl)-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine-1-carbonitrile;6-(1,1-difluoroethyl)-8-methyl-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;3-(1,1-difluoroethyl)-6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]imidazo[1,5-a]pyridine-1-carbonitrile;6-(1,1-difluoroethyl)-3-[4-(trifluoromethyl)phenyl]imidazo[1,5-a]pyrimidine
CID 157071658
3-[difluoro(methoxy)methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1-fluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1-fluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1-fluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1-fluoroethyl)-6-[2-methyl-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1-fluoroethyl)-6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(2-fluoro-2-methylcyclopropyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-[[(2S)-oxan-2-yl]methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-[[(2R)-oxan-2-yl]methyl]-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
CID 157150882
6-[4-(1,1-Difluoroethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine;6-[4-(1,1-difluoroethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[3,4-f][1,2,4]triazine;3-(difluoromethyl)-6-(4-phenoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;6-(3,5-difluoro-4-phenoxyphenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine;6-(4-phenoxyphenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine;6-(4-phenoxyphenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
CID 157166926
6-(4-Cyclopropyl-2-methoxyphenyl)-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1-difluoroethyl)-6-[2-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1-difluoroethyl)-6-[4-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-b]pyridazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-3-methoxyphenyl]cyclopropane-1-carbonitrile;3-ethyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine
CID 157179546
6-[4-(1-Cyanocyclopropyl)phenyl]-3-(1,1-difluoroethyl)imidazo[1,5-a]pyridine-1-carbonitrile;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]imidazo[1,5-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyrazin-6-yl]phenyl]cyclopropane-1-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine-5-carbonitrile;3-(1-fluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine-1-carbonitrile;6-(3-fluoro-3-methylcyclobutyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine
CID 157183479
3-(1,1-Difluoroethyl)-6-[2-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-(methoxymethyl)-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 157305654
3-(1,1-Difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]imidazo[1,2-a]pyrazine;1-[4-[3-(1,1-difluoroethyl)imidazo[1,2-a]pyrazin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[2-(methoxymethyl)-4-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrazine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyrazine;2-methyl-6-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)imidazo[1,2-a]pyrimidine
CID 157455809
CID 157477009
CID 157477009
3-Cyclopropyl-6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-b]pyridazine;1-[4-[3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(3-fluoro-3-methylcyclobutyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(oxolan-2-ylmethyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(oxolan-3-ylmethyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1,2,2-tetrafluoropropyl)-6-[6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-b]pyridazine
CID 157478349
3-(1,1-Difluoroethyl)-6-[2-methyl-5-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrimidine;3-(1-fluoroethyl)-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;methane;6-[4-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrimidine
CID 157524145
3-Cyclopropyl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;6-[4-(3,3-difluorocyclobutyl)oxyphenyl]-3-(1,1-difluoroethyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-ethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[5-fluoro-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[3-fluoro-4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-fluoro-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-[2-methyl-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine;3-(1,1-difluoroethyl)-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazine;3-propan-2-yl-6-[4-(trifluoromethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazine
CID 157527595

Frequently Asked Questions

What is the IUPAC name of 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine?
The IUPAC name of 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine (CID 160667924) is 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine.
What is the SMILES notation for 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine?
The canonical SMILES for 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine is CC(F)(F)c1nc(C#N)c2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(C4(C#N)CC4)cc3)cn12.CC(F)(F)c1ncc2ccc(-c3ccc(OC(F)(F)F)cc3)nn12.CC(F)(F)c1ncc2cnc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.CC(F)c1ncc2ncc(-c3ccc(OC(F)(F)F)cc3)cn12.COC(C)(C)c1ccc(-c2ccc3cnc(C(C)(F)F)n3c2)cc1.COc1cc(OC(F)(F)F)ccc1-c1ccc2cnc(C(C)(F)F)n2c1.
What is the InChIKey of 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine?
The InChIKey is RMNZLBLDLMMWMS-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H15F2N3.C19H20F2N2O.C17H13F5N2O2.C16H9F5N4O.3C15H10F5N3O.C15H11F4N3O/c1-18(20,21)17-23-10-16-7-4-14(11-24(16)17)13-2-5-15(6-3-13)19(12-22)8-9-19;1-18(2,24-4)15-8-5-13(6-9-15)14-7-10-16-11-22-17(19(3,20)21)23(16)12-14;1-16(18,19)15-23-8-11-4-3-10(9-24(11)15)13-6-5-12(7-14(13)25-2)26-17(20,21)22;1-15(17,18)14-24-12(6-22)13-23-7-10(8-25(13)14)9-2-4-11(5-3-9)26-16(19,20)21;1-14(16,17)13-21-8-10-4-7-12(22-23(10)13)9-2-5-11(6-3-9)24-15(18,19)20;1-14(16,17)13-22-7-12-21-6-10(8-23(12)13)9-2-4-11(5-3-9)24-15(18,19)20;1-14(16,17)13-22-7-10-6-21-12(8-23(10)13)9-2-4-11(5-3-9)24-15(18,19)20;1-9(16)14-21-7-13-20-6-11(8-22(13)14)10-2-4-12(5-3-10)23-15(17,18)19/h2-7,10-11H,8-9H2,1H3;5-12H,1-4H3;3-9H,1-2H3;2-5,7-8H,1H3;3*2-8H,1H3;2-9H,1H3.
What are the key properties of 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine?
1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine has a molecular weight of 2749.31 g/mol, XLogP of 36.51, 26 rotatable bonds, 0 hydrogen bond donors, and 31 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[4-[3-(1,1-difluoroethyl)imidazo[1,5-a]pyridin-6-yl]phenyl]cyclopropane-1-carbonitrile;3-(1,1-difluoroethyl)-6-[4-(2-methoxypropan-2-yl)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[2-methoxy-4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyridine;3-(1,1-difluoroethyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine;6-(1,1-difluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine-8-carbonitrile;7-(1,1-difluoroethyl)-2-[4-(trifluoromethoxy)phenyl]imidazo[1,5-b]pyridazine;6-(1-fluoroethyl)-3-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrimidine is sourced from PubChem (CID 160667924), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).