5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione

C88H50F18N12O8S4 — CID 160668682

About 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione

5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione (PubChem CID 160668682) has the molecular formula C88H50F18N12O8S4 and a molecular weight of 1873.68 g/mol. Its IUPAC name is 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione.

Molecular Properties

• Compound Name: 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione
• PubChem CID: 160668682
• Molecular Formula: C88H50F18N12O8S4
• Molecular Weight: 1873.68 g/mol
• Exact Mass: 1872.25
• IUPAC Name: 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione
• SMILES: O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1c(F)cc(-c2ccc(C(F)(F)F)s2)cc1F.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)c(F)c1.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)c(F)c1F.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)cc1F
• InChI: InChI=1S/2C22H12F5N3O2S.2C22H13F4N3O2S/c23-13-7-11(16-3-4-17(33-16)22(25,26)27)8-14(24)18(13)19-20(31)29-21(32)30(19)12-2-1-10-5-6-28-15(10)9-12;23-17-12(15-5-6-16(33-15)22(25,26)27)3-4-13(18(17)24)19-20(31)29-21(32)30(19)11-2-1-10-7-8-28-14(10)9-11;23-15-9-12(2-4-14(15)17-5-6-18(32-17)22(24,25)26)19-20(30)28-21(31)29(19)13-3-1-11-7-8-27-16(11)10-13;23-15-9-12(17-5-6-18(32-17)22(24,25)26)2-4-14(15)19-20(30)28-21(31)29(19)13-3-1-11-7-8-27-16(11)10-13/h1-4,6-9,19H,5H2,(H,29,31,32);1-6,8-9,19H,7H2,(H,29,31,32);2*1-6,8-10,19H,7H2,(H,28,30,31)
• InChIKey: RMQKMMOZJFJNTB-UHFFFAOYSA-N
• XLogP: 22.79
• TPSA: 247.08 Ų
• H-Bond Donors: 4
• H-Bond Acceptors: 16
• Rotatable Bonds: 12
• Heavy Atoms: 130
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	1873.68
LogP ≤ 5	22.79
H-Bond Donors ≤ 5	4
H-Bond Acceptors ≤ 10	16

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydantoin', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione?

The IUPAC name of 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione (CID 160668682) is 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione.

What is the SMILES notation for 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione?

The canonical SMILES for 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione is O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1c(F)cc(-c2ccc(C(F)(F)F)s2)cc1F.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)c(F)c1.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)c(F)c1F.O=C1NC(=O)N(c2ccc3c(c2)N=CC3)C1c1ccc(-c2ccc(C(F)(F)F)s2)cc1F.

What is the InChIKey of 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione?

The InChIKey is RMQKMMOZJFJNTB-UHFFFAOYSA-N. The full InChI is InChI=1S/2C22H12F5N3O2S.2C22H13F4N3O2S/c23-13-7-11(16-3-4-17(33-16)22(25,26)27)8-14(24)18(13)19-20(31)29-21(32)30(19)12-2-1-10-5-6-28-15(10)9-12;23-17-12(15-5-6-16(33-15)22(25,26)27)3-4-13(18(17)24)19-20(31)29-21(32)30(19)11-2-1-10-7-8-28-14(10)9-11;23-15-9-12(2-4-14(15)17-5-6-18(32-17)22(24,25)26)19-20(30)28-21(31)29(19)13-3-1-11-7-8-27-16(11)10-13;23-15-9-12(17-5-6-18(32-17)22(24,25)26)2-4-14(15)19-20(30)28-21(31)29(19)13-3-1-11-7-8-27-16(11)10-13/h1-4,6-9,19H,5H2,(H,29,31,32);1-6,8-9,19H,7H2,(H,29,31,32);2*1-6,8-10,19H,7H2,(H,28,30,31).

What are the key properties of 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione?

5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione has a molecular weight of 1873.68 g/mol, XLogP of 22.79, 12 rotatable bonds, 4 hydrogen bond donors, and 16 hydrogen bond acceptors.

Where does this data come from?

All data for 5-[2,3-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2,6-difluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[2-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione;5-[3-fluoro-4-[5-(trifluoromethyl)thiophen-2-yl]phenyl]-1-(3H-indol-6-yl)imidazolidine-2,4-dione is sourced from PubChem (CID 160668682), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).