2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one

C119H83F25N30O8S2 — CID 160685595

IUPAC2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
SMILESCN1C(=O)C(c2ccc(F)c(-c3ccoc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3ccsc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cnc(F)nc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cocn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cscn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.Cc1ncc(-c2cc(C3(c4cc(C(F)(F)F)ccn4)N=C(N)N(C)C3=O)ccc2F)cn1
InChIInChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H13F4N5O2.C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)17-8-14(5-6-27-17)21(23,24)25;1-31-16(32)19(30-18(31)26,15-7-12(4-5-27-15)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,16-9-13(4-6-26-16)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;2*1-28-16(29)18(27-17(28)24,15-7-11(4-5-25-15)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2*2-9H,1H3,(H2,24,27)
InChIKeyROSJGFBWFGBORV-UHFFFAOYSA-N
MW2600.26 g/mol
LogP19.75
Rot. Bonds18

About 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one

2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one (PubChem CID 160685595) has the molecular formula C119H83F25N30O8S2 and a molecular weight of 2600.26 g/mol. Its IUPAC name is 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one.

Molecular Properties

Compound Name2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
PubChem CID160685595
Molecular FormulaC119H83F25N30O8S2
Molecular Weight2600.26 g/mol
Exact Mass2598.61
IUPAC Name2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one
SMILESCN1C(=O)C(c2ccc(F)c(-c3ccoc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3ccsc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cnc(F)nc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cocn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cscn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.Cc1ncc(-c2cc(C3(c4cc(C(F)(F)F)ccn4)N=C(N)N(C)C3=O)ccc2F)cn1
InChIInChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H13F4N5O2.C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)17-8-14(5-6-27-17)21(23,24)25;1-31-16(32)19(30-18(31)26,15-7-12(4-5-27-15)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,16-9-13(4-6-26-16)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;2*1-28-16(29)18(27-17(28)24,15-7-11(4-5-25-15)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2*2-9H,1H3,(H2,24,27)
InChIKeyROSJGFBWFGBORV-UHFFFAOYSA-N
XLogP19.75
TPSA533.10 Ų
H-Bond Donors6
H-Bond Acceptors34
Rotatable Bonds18
Heavy Atoms184
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002600.26
LogP ≤ 519.75
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1034

Analyze 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one with MolForge

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Launch Full Analysis

Related Compounds

2-[4-(1,1-Difluoroethyl)-2-pyridinyl]-1-(3-fluoro-5-pyrimidin-5-yloxyphenyl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(5-fluoro-4-methyl-1,3-thiazol-2-yl)ethanone;1-[3-fluoro-5-[methyl(pyrimidin-5-yl)amino]phenyl]-2-(1,3-thiazol-2-yl)ethanone;1-(3-methyl-5-pyrimidin-5-yloxyphenyl)-2-(5-methyl-1,3-thiazol-2-yl)ethanone;2-(4-methyl-1,3-thiazol-2-yl)-1-(3-pyrimidin-5-yloxyphenyl)ethanone
CID 123315204
6-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)pyridine-2-carboxamide;2-(1,1-difluoroethyl)-N-(5-pyrimidin-5-yloxy-3-pyridinyl)-1,3-thiazole-4-carboxamide;4-ethynyl-N-(5-pyrimidin-5-yloxy-3-pyridinyl)thiophene-2-carboxamide;4-fluoro-N-(5-pyrimidin-5-yloxy-3-pyridinyl)pyridine-2-carboxamide;3-methyl-N-(5-pyrimidin-5-yloxy-3-pyridinyl)benzamide;6-methyl-N-(5-pyrimidin-5-yloxy-3-pyridinyl)pyridine-2-carboxamide
CID 123921060
2-[4-(2-acetyl-1,3-thiazol-5-yl)-5-methyl-1,3-thiazol-2-yl]-1-(2,6-difluorophenyl)ethanone;tert-butyl N-[5-isoquinolin-6-yl-4-(1,3-oxazol-5-yl)-1,3-thiazol-2-yl]-N-[2-methyl-3-(4-methylphenyl)propyl]carbamate;1-(2,6-difluorophenyl)-2-[4-(3-methylimidazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(4-methyl-1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;1-(2,6-difluorophenyl)-2-[4-(1,3-oxazol-5-yl)-5-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanone;ethene;N-[4-(4-methyl-2-pyrazin-2-yl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]-N-(morpholin-4-ylmethyl)thiophene-2-carboxamide;sulfane
CID 157174043
CID 157454770
CID 157454770
(5Z)-5-[[2-[[4-[[4-fluoro-2-(furan-2-yl)phenyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[1-(6-thiophen-3-yl-2-pyridinyl)ethylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[(6-thiophen-2-yl-2-pyridinyl)methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione;(5Z)-5-[[2-[[4-[[6-[2-(trifluoromethyl)phenyl]-2-pyridinyl]methylamino]cyclohexyl]methyl]pyrimidin-4-yl]methylidene]thiolane-2,4-dione
CID 157512391
N-[(2S)-1-[[4-[4-(6-amino-5-methoxy-3-pyridinyl)-2-[4-(trifluoromethyl)phenyl]-1,3-oxazol-5-yl]pyrimidin-2-yl]amino]propan-2-yl]-2-methoxyacetamide;5-[2-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazol-4-yl]-3-methoxypyridin-2-amine;5-[2-(4-fluorophenyl)-5-pyridin-4-yl-1,3-thiazol-4-yl]-3-methoxypyridin-2-amine;3-methoxy-5-(2-phenyl-4-pyridin-4-yl-1,3-thiazol-5-yl)pyrazin-2-amine;3-methoxy-5-(2-phenyl-4-pyridin-4-yl-1,3-thiazol-5-yl)pyridin-2-amine
CID 157731774
6-(1,1-difluoroethyl)-N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)pyridine-2-carboxamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-6-methoxypyridine-2-carboxamide;bis(N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-6-methylpyridine-2-carboxamide);N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-1,3-thiazole-2-carboxamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-1,3-thiazole-4-carboxamide;methane
CID 157835730
2-(1,1-difluoroethyl)-N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-1,3-thiazole-4-carboxamide;3-ethynyl-N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)benzamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-3-methylbenzamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-4-methylpyridine-2-carboxamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-1,3-thiazole-2-carboxamide;N-(3-fluoro-5-pyrimidin-5-yloxyphenyl)-1,3-thiazole-4-carboxamide
CID 158005809
8-[(2-cyclopentylfuran-3-yl)methyl]-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-6-[2-(oxan-2-yl)ethynyl]pyrido[2,3-d]pyrimidin-7-one;6-[2-(diethylamino)ethynyl]-8-(2-methoxyethyl)-2-[4-[methyl(piperidin-4-yl)amino]anilino]pyrido[2,3-d]pyrimidin-7-one;3-[2-(3-fluoro-4-piperazin-1-ylanilino)-7-oxo-8-[(4-propan-2-yl-1,3-thiazol-5-yl)methyl]pyrido[2,3-d]pyrimidin-6-yl]-N,N-dimethylprop-2-ynamide;6-[2-(1-methylimidazol-2-yl)ethynyl]-2-[4-[(1-methylpiperidin-3-yl)amino]anilino]-8-[[3-(trifluoromethyl)furan-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one;molecular hydrogen
CID 158240940
6-(4-cyclopentyl-2-methylphenyl)-2-[4-[(1-methylpiperidin-4-yl)amino]anilino]-8-(oxan-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;6-(5-cyclopentyl-3-methyl-2-pyridinyl)-2-[4-[methyl(piperidin-3-yl)amino]anilino]-8-(2-oxo-2-pyrrolidin-1-ylethyl)pyrido[2,3-d]pyrimidin-7-one;6-(5-cyclopentyl-3-methyl-3H-pyrrol-2-yl)-2-[4-[(1-methylpiperidin-3-yl)amino]anilino]-8-(1,3-thiazol-2-ylmethyl)pyrido[2,3-d]pyrimidin-7-one;2-(3-fluoro-4-piperazin-1-ylanilino)-6-[5-(3H-pyrrol-5-yl)-2-pyridinyl]-8-(2,2,2-trifluoroethyl)pyrido[2,3-d]pyrimidin-7-one;2-[4-[methyl(piperidin-3-yl)amino]anilino]-6-[2-(1,3-oxazol-2-yl)pyrimidin-5-yl]-8-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidin-7-one
CID 158486313
4-(cyclopropylmethoxy)-5-fluoro-6-[3-[4-[(2R)-4-methylpent-4-en-2-yl]phenoxy]pyrrolidin-1-yl]pyrimidine;N-[5-[(3R)-3-[4-[1-[6-(cyclopropylmethoxy)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]butanoyl]-4-methyl-1,3-thiazol-2-yl]acetamide;(3R)-3-[4-[1-[6-(cyclopropylmethoxy)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N,N-dimethylbutanamide;(3R)-3-[4-[1-[6-(cyclopropylmethoxy)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-1-(1,3-oxazol-5-yl)butan-1-one;5-[(2,2-difluorocyclopropyl)methoxy]-2-[3-[4-[(2R)-4-methylpent-4-en-2-yl]phenoxy]pyrrolidin-1-yl]pyridine;(3R)-3-[4-[1-[2-[2,2-difluoroethyl(methyl)amino]pyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]-N,N-dimethylbutanamide;methyl (3R)-3-[4-[1-[6-(cyclopropylmethoxy)-5-fluoropyrimidin-4-yl]pyrrolidin-3-yl]oxyphenyl]butanoate
CID 158568938
CID 158690568
CID 158690568

Frequently Asked Questions

What is the IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one?
The IUPAC name of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one (CID 160685595) is 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one.
What is the SMILES notation for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one?
The canonical SMILES for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one is CN1C(=O)C(c2ccc(F)c(-c3ccoc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3ccsc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cnc(F)nc3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cocn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.CN1C(=O)C(c2ccc(F)c(-c3cscn3)c2)(c2cc(C(F)(F)F)ccn2)N=C1N.Cc1ncc(-c2cc(C3(c4cc(C(F)(F)F)ccn4)N=C(N)N(C)C3=O)ccc2F)cn1.
What is the InChIKey of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one?
The InChIKey is ROSJGFBWFGBORV-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H16F4N6O.C20H13F5N6O.C20H14F4N4O2.C20H14F4N4OS.C19H13F4N5O2.C19H13F4N5OS/c1-11-28-9-12(10-29-11)15-7-13(3-4-16(15)22)20(18(32)31(2)19(26)30-20)17-8-14(5-6-27-17)21(23,24)25;1-31-16(32)19(30-18(31)26,15-7-12(4-5-27-15)20(23,24)25)11-2-3-14(21)13(6-11)10-8-28-17(22)29-9-10;2*1-28-17(29)19(27-18(28)25,16-9-13(4-6-26-16)20(22,23)24)12-2-3-15(21)14(8-12)11-5-7-30-10-11;2*1-28-16(29)18(27-17(28)24,15-7-11(4-5-25-15)19(21,22)23)10-2-3-13(20)12(6-10)14-8-30-9-26-14/h3-10H,1-2H3,(H2,26,30);2-9H,1H3,(H2,26,30);2*2-10H,1H3,(H2,25,27);2*2-9H,1H3,(H2,24,27).
What are the key properties of 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one?
2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one has a molecular weight of 2600.26 g/mol, XLogP of 19.75, 18 rotatable bonds, 6 hydrogen bond donors, and 34 hydrogen bond acceptors.
Where does this data come from?
All data for 2-amino-5-[4-fluoro-3-(2-fluoropyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(furan-3-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(2-methylpyrimidin-5-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-oxazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-[4-fluoro-3-(1,3-thiazol-4-yl)phenyl]-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one;2-amino-5-(4-fluoro-3-thiophen-3-ylphenyl)-3-methyl-5-[4-(trifluoromethyl)-2-pyridinyl]imidazol-4-one is sourced from PubChem (CID 160685595), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).