(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone

C164H178F24N26O16S — CID 160694254

IUPAC(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
SMILESC=C1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CN1C.CC1(C)Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CO1.CN1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CC1=O.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CC(C)(C)OC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCOC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCS(=O)(=O)C2.O=C1CCc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2C1.O=C1CCc2c(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n[nH]c2C1
InChIInChI=1S/C22H26F3N3O2.C21H23F3N4O.C21H24F3N3O2.C20H21F3N4O2.C20H22F3N3O3S.C20H22F3N3O2.2C20H20F3N3O2/c1-21(2)12-18-16(13-30-21)19(26-27(18)3)20(29)28-10-8-14(9-11-28)15-6-4-5-7-17(15)22(23,24)25;1-13-11-18-16(12-27(13)2)19(26-25-18)20(29)28-9-7-14(8-10-28)15-5-3-4-6-17(15)21(22,23)24;1-20(2)11-17-15(12-29-20)18(26-25-17)19(28)27-9-7-13(8-10-27)14-5-3-4-6-16(14)21(22,23)24;1-26-11-16-14(10-17(26)28)18(25-24-16)19(29)27-8-6-12(7-9-27)13-4-2-3-5-15(13)20(21,22)23;1-25-17-8-11-30(28,29)12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;1-25-17-8-11-28-12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-11-13(27)5-6-17(15)24-25-18;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-6-5-13(27)11-17(15)24-25-18/h4-7,14H,8-13H2,1-3H3;3-6,14H,1,7-12H2,2H3,(H,25,26);3-6,13H,7-12H2,1-2H3,(H,25,26);2-5,12H,6-11H2,1H3,(H,24,25);2-5,13H,6-12H2,1H3;2-5,13H,6-12H2,1H3;2*1-4,12H,5-11H2,(H,24,25)
InChIKeyRPUJTZXOERKNKI-UHFFFAOYSA-N
MW3257.41 g/mol
LogP29.00
Rot. Bonds16

About (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone

(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone (PubChem CID 160694254) has the molecular formula C164H178F24N26O16S and a molecular weight of 3257.41 g/mol. Its IUPAC name is (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone.

Molecular Properties

Compound Name(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
PubChem CID160694254
Molecular FormulaC164H178F24N26O16S
Molecular Weight3257.41 g/mol
Exact Mass3255.33
IUPAC Name(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
SMILESC=C1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CN1C.CC1(C)Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CO1.CN1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CC1=O.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CC(C)(C)OC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCOC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCS(=O)(=O)C2.O=C1CCc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2C1.O=C1CCc2c(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n[nH]c2C1
InChIInChI=1S/C22H26F3N3O2.C21H23F3N4O.C21H24F3N3O2.C20H21F3N4O2.C20H22F3N3O3S.C20H22F3N3O2.2C20H20F3N3O2/c1-21(2)12-18-16(13-30-21)19(26-27(18)3)20(29)28-10-8-14(9-11-28)15-6-4-5-7-17(15)22(23,24)25;1-13-11-18-16(12-27(13)2)19(26-25-18)20(29)28-9-7-14(8-10-28)15-5-3-4-6-17(15)21(22,23)24;1-20(2)11-17-15(12-29-20)18(26-25-17)19(28)27-9-7-13(8-10-27)14-5-3-4-6-16(14)21(22,23)24;1-26-11-16-14(10-17(26)28)18(25-24-16)19(29)27-8-6-12(7-9-27)13-4-2-3-5-15(13)20(21,22)23;1-25-17-8-11-30(28,29)12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;1-25-17-8-11-28-12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-11-13(27)5-6-17(15)24-25-18;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-6-5-13(27)11-17(15)24-25-18/h4-7,14H,8-13H2,1-3H3;3-6,14H,1,7-12H2,2H3,(H,25,26);3-6,13H,7-12H2,1-2H3,(H,25,26);2-5,12H,6-11H2,1H3,(H,24,25);2-5,13H,6-12H2,1H3;2-5,13H,6-12H2,1H3;2*1-4,12H,5-11H2,(H,24,25)
InChIKeyRPUJTZXOERKNKI-UHFFFAOYSA-N
XLogP29.00
TPSA478.86 Ų
H-Bond Donors5
H-Bond Acceptors28
Rotatable Bonds16
Heavy Atoms231
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5003257.41
LogP ≤ 529.00
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1028

Analyze (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone with MolForge

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Related Compounds

(5,5-dioxo-1,4,6,7-tetrahydrothiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6,7,8-hexahydrocyclohepta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(1,4,5,6-tetrahydrocyclopenta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);bis(4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);4,6,7,8-tetrahydro-1H-oxepino[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,6,7-tetrahydropyrano[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 158038250
[1-ethyl-6-(methyl-methylidene-oxo-lambda6-sulfanyl)-5,7-dihydro-4H-pyrazolo[5,4-c]pyridin-3-yl]-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-4,6,7,8-tetrahydropyrazolo[4,3-c]azepin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6-tetrahydrocyclopenta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);4,6,7,8-tetrahydro-1H-oxepino[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 158049145
(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-4,5,6,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone)
CID 159265850
(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6,7,8-hexahydrocyclohepta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6-tetrahydrocyclopenta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);4,6,7,8-tetrahydro-1H-oxepino[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,6,7-tetrahydropyrano[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
CID 159276613
[1-ethyl-6-(methyl-methylidene-oxo-lambda6-sulfanyl)-5,7-dihydro-4H-pyrazolo[5,4-c]pyridin-3-yl]-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,6,7-tetrahydropyrano[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 159280201
4,6-dihydro-1H-furo[3,4-d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;[1-ethyl-6-(methyl-methylidene-oxo-lambda6-sulfanyl)-5,7-dihydro-4H-pyrazolo[5,4-c]pyridin-3-yl]-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-4,6-dihydropyrrolo[3,4-d]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-ethyl-5-methylsulfonyl-5,6,7,8-tetrahydro-4H-cyclohepta[c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5-methylsulfonyl-4,6,7,8-tetrahydropyrazolo[4,3-c]azepin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 159850915
(6,6-dioxo-1,4,5,7-tetrahydrothiopyrano[4,3-d]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6,7,8-hexahydrocyclohepta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(1,4,5,6-tetrahydrocyclopenta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;4,6,7,8-tetrahydro-1H-oxepino[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,6,7-tetrahydropyrano[4,3-c]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,7-tetrahydropyrano[4,3-d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone
CID 160061223
(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(6-methylidene-1,4,5,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-4,5,6,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
CID 160381764
(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-4,5,6,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one
CID 161889098
(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;1,4,5,6,7,8-hexahydrocyclohepta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis((1-methyl-4,5,6,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);1,4,5,6-tetrahydrocyclopenta[d]pyrazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;bis(4,5,6,7-tetrahydro-1H-indazol-3-yl-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone);[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
CID 162004662
(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methylidene-1,4,6,7-tetrahydropyrazolo[5,4-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-4,5,6,7-tetrahydroindazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydropyrazolo[4,3-c]pyridin-6-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone
CID 163963647

Frequently Asked Questions

What is the IUPAC name of (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone?
The IUPAC name of (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone (CID 160694254) is (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone.
What is the SMILES notation for (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone?
The canonical SMILES for (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone is C=C1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CN1C.CC1(C)Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CO1.CN1Cc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2CC1=O.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CC(C)(C)OC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCOC2.Cn1nc(C(=O)N2CCC(c3ccccc3C(F)(F)F)CC2)c2c1CCS(=O)(=O)C2.O=C1CCc2[nH]nc(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)c2C1.O=C1CCc2c(C(=O)N3CCC(c4ccccc4C(F)(F)F)CC3)n[nH]c2C1.
What is the InChIKey of (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone?
The InChIKey is RPUJTZXOERKNKI-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H26F3N3O2.C21H23F3N4O.C21H24F3N3O2.C20H21F3N4O2.C20H22F3N3O3S.C20H22F3N3O2.2C20H20F3N3O2/c1-21(2)12-18-16(13-30-21)19(26-27(18)3)20(29)28-10-8-14(9-11-28)15-6-4-5-7-17(15)22(23,24)25;1-13-11-18-16(12-27(13)2)19(26-25-18)20(29)28-9-7-14(8-10-28)15-5-3-4-6-17(15)21(22,23)24;1-20(2)11-17-15(12-29-20)18(26-25-17)19(28)27-9-7-13(8-10-27)14-5-3-4-6-16(14)21(22,23)24;1-26-11-16-14(10-17(26)28)18(25-24-16)19(29)27-8-6-12(7-9-27)13-4-2-3-5-15(13)20(21,22)23;1-25-17-8-11-30(28,29)12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;1-25-17-8-11-28-12-15(17)18(24-25)19(27)26-9-6-13(7-10-26)14-4-2-3-5-16(14)20(21,22)23;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-11-13(27)5-6-17(15)24-25-18;21-20(22,23)16-4-2-1-3-14(16)12-7-9-26(10-8-12)19(28)18-15-6-5-13(27)11-17(15)24-25-18/h4-7,14H,8-13H2,1-3H3;3-6,14H,1,7-12H2,2H3,(H,25,26);3-6,13H,7-12H2,1-2H3,(H,25,26);2-5,12H,6-11H2,1H3,(H,24,25);2-5,13H,6-12H2,1H3;2-5,13H,6-12H2,1H3;2*1-4,12H,5-11H2,(H,24,25).
What are the key properties of (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone?
(6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone has a molecular weight of 3257.41 g/mol, XLogP of 29.00, 16 rotatable bonds, 5 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for (6,6-dimethyl-4,7-dihydro-1H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-6,7-dihydro-4H-pyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(1-methyl-5,5-dioxo-6,7-dihydro-4H-thiopyrano[4,3-c]pyrazol-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;(5-methyl-6-methylidene-4,7-dihydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]methanone;6-methyl-3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-4,7-dihydro-1H-pyrazolo[5,4-c]pyridin-5-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,5,7-tetrahydroindazol-6-one;3-[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]-1,4,6,7-tetrahydroindazol-5-one;[4-[2-(trifluoromethyl)phenyl]piperidin-1-yl]-(1,6,6-trimethyl-4,7-dihydropyrano[4,3-c]pyrazol-3-yl)methanone is sourced from PubChem (CID 160694254), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).