1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one

C149H121F20N25O12 — CID 160697012

About 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one

1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one (PubChem CID 160697012) has the molecular formula C149H121F20N25O12 and a molecular weight of 2833.73 g/mol. Its IUPAC name is 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one.

Molecular Properties

• Compound Name: 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one
• PubChem CID: 160697012
• Molecular Formula: C149H121F20N25O12
• Molecular Weight: 2833.73 g/mol
• Exact Mass: 2831.93
• IUPAC Name: 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one
• SMILES: O=C(c1cc(-c2ccncc2)n(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)c(F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)c(F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2ccc3c(c2)OCO3)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1
• InChI: InChI=1S/C31H25F6N5O2.C30H23F6N5O2.C30H25F4N5O2.C29H23F4N5O2.C29H25N5O4/c32-30(33,34)21-16-22(31(35,36)37)18-24(17-21)42-26(20-6-11-38-12-7-20)19-25(39-42)28(44)40-14-9-29(10-15-40)27(43)8-13-41(29)23-4-2-1-3-5-23;31-29(32,33)20-14-21(30(34,35)36)16-23(15-20)41-26(18-5-9-37-10-6-18)17-24(38-41)28(43)39-11-7-22(8-12-39)40-25-4-2-1-3-19(25)13-27(40)42;31-24-18-22(6-7-23(24)30(32,33)34)39-26(20-8-13-35-14-9-20)19-25(36-39)28(41)37-16-11-29(12-17-37)27(40)10-15-38(29)21-4-2-1-3-5-21;30-23-16-21(5-6-22(23)29(31,32)33)38-26(18-7-11-34-12-8-18)17-24(35-38)28(40)36-13-9-20(10-14-36)37-25-4-2-1-3-19(25)15-27(37)39;35-28-15-20-3-1-2-4-24(20)33(28)21-9-13-32(14-10-21)29(36)23-17-25(19-7-11-30-12-8-19)34(31-23)22-5-6-26-27(16-22)38-18-37-26/h1-7,11-12,16-19H,8-10,13-15H2;1-6,9-10,14-17,22H,7-8,11-13H2;1-9,13-14,18-19H,10-12,15-17H2;1-8,11-12,16-17,20H,9-10,13-15H2;1-8,11-12,16-17,21H,9-10,13-15,18H2
• InChIKey: RQCYKUACTSGLBI-UHFFFAOYSA-N
• XLogP: 27.28
• TPSA: 375.11 Ų
• H-Bond Acceptors: 29
• Rotatable Bonds: 20
• Heavy Atoms: 206
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2833.73
LogP ≤ 5	27.28
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	29

Frequently Asked Questions

What is the IUPAC name of 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The IUPAC name of 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one (CID 160697012) is 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one.

What is the SMILES notation for 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The canonical SMILES for 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one is O=C(c1cc(-c2ccncc2)n(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)c(F)c2)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.O=C(c1cc(-c2ccncc2)n(-c2ccc(C(F)(F)F)c(F)c2)n1)N1CCC2(CC1)C(=O)CCN2c1ccccc1.O=C(c1cc(-c2ccncc2)n(-c2ccc3c(c2)OCO3)n1)N1CCC(N2C(=O)Cc3ccccc32)CC1.

What is the InChIKey of 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

The InChIKey is RQCYKUACTSGLBI-UHFFFAOYSA-N. The full InChI is InChI=1S/C31H25F6N5O2.C30H23F6N5O2.C30H25F4N5O2.C29H23F4N5O2.C29H25N5O4/c32-30(33,34)21-16-22(31(35,36)37)18-24(17-21)42-26(20-6-11-38-12-7-20)19-25(39-42)28(44)40-14-9-29(10-15-40)27(43)8-13-41(29)23-4-2-1-3-5-23;31-29(32,33)20-14-21(30(34,35)36)16-23(15-20)41-26(18-5-9-37-10-6-18)17-24(38-41)28(43)39-11-7-22(8-12-39)40-25-4-2-1-3-19(25)13-27(40)42;31-24-18-22(6-7-23(24)30(32,33)34)39-26(20-8-13-35-14-9-20)19-25(36-39)28(41)37-16-11-29(12-17-37)27(40)10-15-38(29)21-4-2-1-3-5-21;30-23-16-21(5-6-22(23)29(31,32)33)38-26(18-7-11-34-12-8-18)17-24(35-38)28(40)36-13-9-20(10-14-36)37-25-4-2-1-3-19(25)15-27(37)39;35-28-15-20-3-1-2-4-24(20)33(28)21-9-13-32(14-10-21)29(36)23-17-25(19-7-11-30-12-8-19)34(31-23)22-5-6-26-27(16-22)38-18-37-26/h1-7,11-12,16-19H,8-10,13-15H2;1-6,9-10,14-17,22H,7-8,11-13H2;1-9,13-14,18-19H,10-12,15-17H2;1-8,11-12,16-17,20H,9-10,13-15H2;1-8,11-12,16-17,21H,9-10,13-15,18H2.

What are the key properties of 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one?

1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one has a molecular weight of 2833.73 g/mol, XLogP of 27.28, 20 rotatable bonds, 0 hydrogen bond donors, and 29 hydrogen bond acceptors.

Where does this data come from?

All data for 1-[1-[1-(1,3-benzodioxol-5-yl)-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3,5-bis(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one;8-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]-1-phenyl-1,8-diazaspiro[4.5]decan-4-one;1-[1-[1-[3-fluoro-4-(trifluoromethyl)phenyl]-5-pyridin-4-ylpyrazole-3-carbonyl]piperidin-4-yl]-3H-indol-2-one is sourced from PubChem (CID 160697012), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).