6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine

C135H168BrF3N32O3S7 — CID 160703627

About 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine

6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine (PubChem CID 160703627) has the molecular formula C135H168BrF3N32O3S7 and a molecular weight of 2648.42 g/mol. Its IUPAC name is 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine.

Molecular Properties

• Compound Name: 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine
• PubChem CID: 160703627
• Molecular Formula: C135H168BrF3N32O3S7
• Molecular Weight: 2648.42 g/mol
• Exact Mass: 2645.12
• IUPAC Name: 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine
• SMILES: Brc1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1.CC(=O)Nc1ccc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)cn1.CC(=O)c1cccc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)sc3c2)c1.COc1cc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)ccn1.FC(F)(F)c1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1.N#Cc1cc2sc(N3CCC(N4CCCCC4)CC3)nc2cn1.c1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1
• InChI: InChI=1S/C24H28N4OS.C23H28N6OS.C22H27N5OS.C17H21F3N4S.C17H21N5S.C16H21BrN4S.C16H22N4S/c1-17(29)18-6-5-7-19(14-18)20-15-22-23(25-16-20)26-24(30-22)28-12-8-21(9-13-28)27-10-3-2-4-11-27;1-16(30)26-22-6-5-17(14-25-22)19-13-21-20(15-24-19)27-23(31-21)29-11-7-18(8-12-29)28-9-3-2-4-10-28;1-28-21-13-16(5-8-23-21)18-14-20-19(15-24-18)25-22(29-20)27-11-6-17(7-12-27)26-9-3-2-4-10-26;18-17(19,20)12-10-14-15(21-11-12)22-16(25-14)24-8-4-13(5-9-24)23-6-2-1-3-7-23;18-11-13-10-16-15(12-19-13)20-17(23-16)22-8-4-14(5-9-22)21-6-2-1-3-7-21;17-12-10-14-15(18-11-12)19-16(22-14)21-8-4-13(5-9-21)20-6-2-1-3-7-20;1-2-9-19(10-3-1)13-6-11-20(12-7-13)16-18-15-14(21-16)5-4-8-17-15/h5-7,14-16,21H,2-4,8-13H2,1H3;5-6,13-15,18H,2-4,7-12H2,1H3,(H,25,26,30);5,8,13-15,17H,2-4,6-7,9-12H2,1H3;10-11,13H,1-9H2;10,12,14H,1-9H2;10-11,13H,1-9H2;4-5,8,13H,1-3,6-7,9-12H2
• InChIKey: RQXYXQRWHMEDQJ-UHFFFAOYSA-N
• XLogP: 27.64
• TPSA: 330.79 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 41
• Rotatable Bonds: 20
• Heavy Atoms: 181
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2648.42
LogP ≤ 5	27.64
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	41

Frequently Asked Questions

What is the IUPAC name of 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine?

The IUPAC name of 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine (CID 160703627) is 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine.

What is the SMILES notation for 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine?

The canonical SMILES for 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine is Brc1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1.CC(=O)Nc1ccc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)cn1.CC(=O)c1cccc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)sc3c2)c1.COc1cc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)ccn1.FC(F)(F)c1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1.N#Cc1cc2sc(N3CCC(N4CCCCC4)CC3)nc2cn1.c1cnc2nc(N3CCC(N4CCCCC4)CC3)sc2c1.

What is the InChIKey of 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine?

The InChIKey is RQXYXQRWHMEDQJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C24H28N4OS.C23H28N6OS.C22H27N5OS.C17H21F3N4S.C17H21N5S.C16H21BrN4S.C16H22N4S/c1-17(29)18-6-5-7-19(14-18)20-15-22-23(25-16-20)26-24(30-22)28-12-8-21(9-13-28)27-10-3-2-4-11-27;1-16(30)26-22-6-5-17(14-25-22)19-13-21-20(15-24-19)27-23(31-21)29-11-7-18(8-12-29)28-9-3-2-4-10-28;1-28-21-13-16(5-8-23-21)18-14-20-19(15-24-18)25-22(29-20)27-11-6-17(7-12-27)26-9-3-2-4-10-26;18-17(19,20)12-10-14-15(21-11-12)22-16(25-14)24-8-4-13(5-9-24)23-6-2-1-3-7-23;18-11-13-10-16-15(12-19-13)20-17(23-16)22-8-4-14(5-9-22)21-6-2-1-3-7-21;17-12-10-14-15(18-11-12)19-16(22-14)21-8-4-13(5-9-21)20-6-2-1-3-7-20;1-2-9-19(10-3-1)13-6-11-20(12-7-13)16-18-15-14(21-16)5-4-8-17-15/h5-7,14-16,21H,2-4,8-13H2,1H3;5-6,13-15,18H,2-4,7-12H2,1H3,(H,25,26,30);5,8,13-15,17H,2-4,6-7,9-12H2,1H3;10-11,13H,1-9H2;10,12,14H,1-9H2;10-11,13H,1-9H2;4-5,8,13H,1-3,6-7,9-12H2.

What are the key properties of 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine?

6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine has a molecular weight of 2648.42 g/mol, XLogP of 27.64, 20 rotatable bonds, 1 hydrogen bond donors, and 41 hydrogen bond acceptors.

Where does this data come from?

All data for 6-bromo-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;6-(2-methoxy-4-pyridinyl)-2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridine;1-[3-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-b]pyridin-6-yl]phenyl]ethanone;2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridine-6-carbonitrile;N-[5-[2-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[4,5-c]pyridin-6-yl]-2-pyridinyl]acetamide;2-(4-piperidin-1-ylpiperidin-1-yl)-6-(trifluoromethyl)-[1,3]thiazolo[4,5-b]pyridine is sourced from PubChem (CID 160703627), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).